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Objective: To compare with two kinds of rat models of visceral hypersensitivity induced by mechanical and chemical factors.

目的 :通过比较评价物理、化学两种机制诱导的内脏痛觉超敏大鼠模型的异同,为肠易激综合征等疾病的药效学评价提供有效、可靠的动物模型。

The increased expression of NMDA-R1 plays an important role in the formation of visceral hypersensitivity.

内脏高敏感的形成与突触后NMDA-R1的高表达密切相关。

And visceral hypersensitivity has been proved to be a pathophysiological characteristic of patients with IBS.

目前证明内脏敏感性增高是其特征性的病理生理基础。

Glucosidase deficiency disease is a rare genetic disorder in which the lysosomal enzyme α-glucosidase is markedly reduced and leads to accumulation of glycogen in various tissues. Its clinical features include massive enlargement of the internal organs, skeletal muscle weakness and hypotonia, and respiratory insufficiency.

阿法-糖苷酶缺乏之全身性糖原质病是一种少见的遗传性疾病,此病主要是因为缺乏阿法-糖苷酶而造成过多的糖原质堆积在各种组识中,导效患者在临床上会有内脏扩大、肌肉无力和呼吸不足等症状。

That in fact, the puss and swelling is caused by indoxyl created by the rotten gut of the protein eaters that dissobey every rule of Nature that God ever gave us humans to follow and as a result, some have resulted to drinking their own urine; something we would expect the monkey in the cage to do out of bordom or maybe he is wanting to commit suicide and is just not able...

事实上,脓和肿胀是因为吃腐朽内脏蛋白的人建造吲哚酚引起的,自然的每个孤独规定,上帝曾经给了我们人类去追求和作为结果,有些结果是去喝他们自己的尿,有些事情我们应该去期待,在笼子中的猴子跑出或大概他没有畏罪自杀和恰好不能。。。

The method has been successfully applied to the determination of 14 PAEs in six animal innards.

该分析方法已成功地应用于6种动物内脏中14种痕量PAEs残留的分析。

They have found that people's bones do much more than just provide scaffolding for their floppy innards.

他们发现,人类的骨骼不仅仅是为松软的内脏提供"脚手架"。

Consider however the strain on your pet's innards.

但是考虑应变对你的宠物的内脏

As you are holding your breath and sucking in, think about pulling your innards up and under your rib-cage.

如你持有的呼吸和吸收,想拉你的内脏,并在你的肋骨笼。

Our digestive system is very similar, albeit not quite as simple, as the innards of that unfortunate automobile.

我们的消化系统很相似,尽管不是很简单,因为内脏那段不幸的汽车。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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