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Result: Isopropyl 3-(3,4-dihydroxyphenyl)-2- hydroxypropanoate exerted relaxation effect on the endothelium-intact artery precontracted by NE in a concentration-dependent manner, which was inhibited with denuded endothelium. The right-shift of the concentration-response curves of 5-HT, ET-1, U46619 and KCl.

结果:丹参素异丙酯可浓度依赖性舒张NE预收缩的完整内皮血管,去内皮后该作用明显降低;对5-羟色胺(5-HT)、内皮素(ET-1),U46619和KCl量效曲线均表现浓度依赖性抑制。

RESULTS:The transendothelial electrical resistance of microvessels superfused with artificial cerebrospinal fluid was about 2 500 Ω*cm2, indicating a tight barrier with extremely low ion permeability, and application of 10-4 mol*L-1 histamine in superfusate caused a rapid and reversible decrease of resistance.

结果:脑软膜微血管经灌流人工脑脊液,测得的跨内皮电阻大约为2 500 Ω*cm2,说明微血管内皮是具有较低通透性的致密屏障,在人工脑脊液中加入10-4 mol*L-1组胺引起跨内皮电阻快速的和可逆性的下降。

Result: The transendothelial electrical resistance of microvessels superfused with artificial cerebrospinal fluid was about 2500 Ω·cm2, indicating a tight barrier with extremely low ion permeability, and application of 10-4 mol·L-1 histamine in superfusate caused a rapid and reversible decrease in transendothelial electrical resistance.

结果 :脑软膜微血管经灌流人工脑脊液,测得的跨内皮电阻大约为 2500Ω·cm2 ,说明微血管内皮是具有较低通透性的致密屏障,在人工脑脊液中加入 10-4 mol·L-1组胺引起跨内皮电阻快速的和可逆性的下降。

The entire process of PMN rolling on, adhering to, and transmigrating across the EC monolayer was recorded under both phase-contrast and fluorescence optics.

我们发现当单一PMN开始穿过内皮细胞层,会引发紧邻的内皮细胞 [Ca2+]i上升,但对其附近未直接接触此一PMN的内皮细胞,则没有影响。

Results VEGF-C and VEGFR-3 are all expressed on both mesenchymal cells and vascular endothelium of the embryos during early period. In middle and latter period, VEGFR-3mRNA is mainly expressed on cell plasm of alimentary canal, but it has no expression on vascular and lymphatic endothelium; The expression of VEGFR-3 is extensive and positive expression is seen on the vascular and lymphatic endothelium.

在胚胎中、后期消化道组织中VEGF-C主要表达于消化管壁组织细胞以及肠系膜内,在血管和淋巴管内皮细胞则无表达;VEGFR-3亦表现为广泛的表达,于血管和淋巴管内皮细胞可见阳性表达,并随着胚胎的发育,其在淋巴管内皮细胞的阳性表达率明显增加。

Results:Berberine inhibited HUVEC adhesion for lymphocyte when pretreated HUVEC and antagonised IL-1 and TNF-induced upregulation of HUVEC adhesion for lymphocyte.Meanwhile,IL-1-stimulated lymphocyte adhesion to HUVEC was diminished in the presence of berberine.The main molecular mechanism of berberines function may be downregulating the expression of ICAM-1 on the HUVEC .

结果:小檗碱能抑制静息的及IL-1、TNF激活的内皮细胞与淋巴细胞间的粘附,其主要分子机制为下调内皮细胞表面粘附分子ICAM-1的表达;小檗碱能抑制IL-1激活的淋巴细胞与内皮细胞的粘附,对淋巴细胞表面粘附分子CD18的表达无影响。

This study investigated endothelial chimerism and its influential factors with X and Y chromosome probes by fluorescence in situ hybridization.

使用X,Y染色体探针通过荧光原位杂交法观察移植肾中血管内皮细胞被受体内皮细胞替代的情况,并分析内皮细胞替代的影响因素。

AIM: Endothelial chimerism refers to endothelial cells from recipients replace original cells.

目的:移植受者来源的内皮细胞出现在供者移植物中,替代原有的细胞,称为内皮替代,也称内皮嵌合。

Abstract] Objective To assess the endothelium-dependent relaxation in patients with essential hypertension or hypertension smokers by color Doppler flow imaging.Methods With intermittent ultrasound imaging and power Doppler imaging,we measured endothelium-dependent relaxing function in 72 subjects 24 of whom with essential hypertension,24 of whom with both hypertension and smokingand the others as normal control.We measured the diameter of the superficial femoral and brachial arteries at rest,during reactive hyperaemia,re-test and after sublingual glyceryl trinitrate for evaluating the endothelium-independent dilatation in subjects.The level of plasma NO,ET,PGI2,and TXB2 were determined.

摘要] 目的探讨原发性高血压及高血压合并吸烟患者血管内皮依赖性舒张功能的改变方法采用彩色普勒高频超声的间歇成像和能量多普勒成像,对24例原发性高血压患者、24例高血压合并吸烟患者及24例正常血压无吸烟史者的血管内皮依赖性舒张功能,包括静息时血管内径、增加流量引起的血管舒张、硝酸甘油引起的血管舒张等,以及对血浆氧化氮、内皮素、血栓素B2(TXB2)和列腺环素(PGI2)等血管活性物质进行检测并比较分析。

Result: 1 HE staining 2 immunohistochemical method:①the positive expressive rate of Bax in proliferative phase and involuting phase of hemangioma, normal skin tissues in turn were

结果 1 HE染色:增生期血管瘤组织中可见条索状或片状内皮细胞增生,其间有不规则的内皮间隙和完整的血管腔,内皮细胞核肥大而淡染。

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