内皮

Therefore, the purpose of this study is to investigate the influence on ECM, level of nitric oxide, and cell death with the addition of vitamin C, E and uric acid in a high-concentration glucose environment.

因次本实验的研究目的在探讨高浓度葡萄糖的环境下，添加维生素C、E与尿酸，对於内皮细胞胞外间质蛋白、一氧化氮含量和细胞死亡的影响。

We detected the expression of VEGF mRNA by in situ hybridization and Ki 67 protein by immune histochemistry.

原位杂交法检测瘤组织血管内皮生长因子mRNA表达；免疫组化法检测瘤组织中细胞增殖核抗原Ki 67的表达。

Objective To link and clone the genes encoding horseradish peroxidase and vascular endothelial growth factor for expression of fusion protein.

目的 连接辣根过氧化物酶基因与血管内皮生长因子基因并进行克隆。

Combined with animal model of peradaptation to myocardium ischemia , the research observed the level of enzymatic dynamics of myocardium, SOD,MDA,ET and correlation peptide of calcitonin gene in peripheral blood and cardiac function, apoptic cell and expression of apoptosis regulatory gene, ultrastructure of myocardium with BIOPAC16, in situ end labeling and hybridism, optic microscope and electron microscope. The study of animal model of peradaptation to myocardium ischemia illustrated that the peradaptation and pretreatment with Wenxin capsule could be positively protective for the injury of ischemia reperfusion. The protection is mainly reflected by reduction of infarction area, correction of heart rhythm abnormality of ischemia reperfusion, melioration of the contraction and relaxation function of myocardium, recovery of the subcellular structure and themelioration of the abnormality of biochemical and bioactive substance in the myocardium.

并结合心肌缺血预适应动物模型，采用BIOPAC16导生理记录和分析处理系统处理心肌功能指标，采用原位末端标记及原位杂交技术标记凋亡细胞及凋亡相关调控基因的表达，采用光电镜技术观察心肌超微结构的变化，同时观察外周血心肌酶、超氧化物歧化酶、丙二醛、内皮素、降钙素基因相关肽等水平，结果表明心肌缺血预适应及温心胶囊预处理对心肌缺血再灌注损伤具有肯定的保护作用，其保护心脏作用主要表现在缩小心肌梗死范围、抗缺血再灌注心律失常、改善心肌收缩和舒张功能、减轻心肌超微结构损伤，调节心肌生化物质及生物活性物质的生成和释放。

Abstract］ Objective To observe the effect of hypercholesterolemia on the expression of VEGF in endothelial cells and the role of simvastatin.

目的 研究高胆固醇血清对血管内皮细胞VEGF表达的影响以及辛伐他汀的抑制作用。

Objective To investigate the effect of cholesterol-lowering therapy with simvastatin on endothelium-dependent relaxing function in patients with hypercholesterolemia.

目的 研究辛伐他汀对原发性高胆固醇血症患者血管内皮依赖性舒张功能的影响。

In the experiment, an approach was made to the cause of DRP and the mechanism of it's prevention and treatmend by acupuncture. The experimental results indicated that in rat with diabetes,(1) plasma TXB2 and the ratio of TXB2 to 6-keto-PGF1α increased obviously, suggesting hyperfunction of platelet and injury to endothelial function, which tend to result in thrombosis;(2) erythrocytic filtration index increased remarkably, suggesting erythrocytic transforming and oxygen carring hypofunction, which is one of the factors leading to retinal anoxia;(3) hyperglycemia persisted, which is related to the thickening of basilar membrane of and the decrease of mural cell of retinal blood vessels;(4) serum growth hormone rose notably, which is not only one of the important factors causing basilar membrane thickening but also promotes the synthesis or Von Willebrand Factor that participates in a tendency to thrombosis.

本实验对糖尿病性视网膜病变（Diabetic Retinopathy，DRP）的成因以及针刺防治DRP的作用机理进行了探讨，实验结果表明：糖尿病大鼠（1）血浆TXB2及TXB2/6-ket0-PGF1α比值均显著升高，提示其血小板机能亢进，内皮细胞功能损伤，具有血栓形成倾向；（2）红细胞滤过指数（Filtration Index，IF）显著增高，提示其红细胞变形能力低下，携氧运行功能降低，是造成视网膜缺氧状态的因素之一；（3）呈持续高血糖状态，与视网膜血管基底膜增厚及管壁细胞减少有关；（4）血清生长激素（Growth Hormone，GH）水平明显升高，既是导致基底膜增厚的重要因素之一，又促进VWF合成，参与血栓形成倾向。

Objective: To investigate the effects of hyperglycemia and hyperinsulinemia on endothelial cell apoptosis and Mn-SOD expression.

目的：了解糖尿病高胰岛素及高血糖的改变对内皮细胞凋亡及Mn-SOD表达的影响。

Introductionratherosclerosis and hypertensin are associated with adherence of blood cell, thrombosis, vasoconstriction and proliferation of vascular smooth muscle.

血管内皮细胞能合成合释放多种血管活性物质，对维持血管的舒缩，抑制血小板的聚集及平滑肌的增殖均具有重要意义。

Objective To investigate the effects of hypertonic saline treatment on the function and susceptibility to sepsis of reticuloendothelial system in mice with hemorrhagic shock.

目的 探讨高渗盐水治疗对失血性休克鼠网状内皮细胞功能和易感染性的影响。

By the time of its fall, most of the prisoners were writers who had written against the corruptions of the government.

到它被攻陷的时候，里面多数的犯人是写了反对政府贪污文章的作家。

The most obvious variation to ovum morphological character was that the color was changed from light green to sepiaceous in embryonic development, and all the ovums were almost hatched after 96h.

在胚胎发育过程中卵的形态特征最明显的变化是颜色从淡绿到深褐色，卵在发育96h后卵基本全部孵化。