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The corneal endothelial cells of the primate have regenerative power, and the form is amitosis.

灵长目动物角膜内皮细胞在一定条件下有再生能力,其再生方式为无丝分裂。

The regenerative form of corneal endothelial cells of the adult, infant and fetal primate was amitosis under both physiologic and pathologic conditions.

成年及幼年灵长目动物角膜内皮细胞在生理和病理条件下的再生方式均为无丝分裂。

Objective To investigate the endothelial injury and dysfunction in patients with unstable angina.

目的 研究不稳定性心绞痛患者内皮细胞的损伤和功能变化。

AIM: To explore the role of poly-polymerase in the cultured endothelial cell apoptosis induced by angiotensin Ⅱ.

目的: 探讨体外AngⅡ在引起血管内皮细胞凋亡过程中细胞内多聚聚合酶的活性变化情况。

Objective To investigate the inhibition of rapamycin in angiotensin Ⅱ-induced vascular endothelial cell proliferation.

目的 免疫抑制剂雷帕霉素对血管紧张素Ⅱ诱导的脐静脉内皮细胞抑制作用机制。

(1) cerebral ischemical reperfusion injury rats'limbs motor function is variable. Acupuncture could promote lims'functional recovery.(2) PCNA masc cells is visible in cerebral ischemical semidarkness region. There is cell regeneration phenomenon. Acupuncture could strengthen injury region's PCNA expression, could profit injury recovery and functional reconstruction.(3) In ischemia semidarkness region for the model group and acupuncture group, PCNA masc cells percentage of 14days group is lower than 7days group. Along with the recovery of injury, cell multiplication is weaken.(4) In cerebral ischemia semidarkness region, there is VEGF masc cells and regeneration phenomenon. Acupuncture could strengthen injury region's VEGF expression, could profit protection after injury and blood vessel regenerate.(5) In ischemia semidarkness region for the model group and acupuncture group, VEGF masc cells percentage of 14days group is lower than 7days group. Along with the recovery of semidarkness region, ischemia and anoxemia state is getting improved, and VEGF is reduce.(6) As there are PCNA and VEGF masc cells in brain injured region, we could conclude that, after brain ischemical reperfusion injury, there are blood vessel regeneration phenomenon. Acupuncture could promote blood vessel regeneration, recovery blood supply sufficiently and quickly, and promote the recovery of brain injury region.(7)The VEGF masc cells percentage of inhibitor group is lower than acupuncture group. It state that the effect of acupuncture promote VEGF is partly depend on the existing of eNOS.

实验结论:(1)脑缺血再灌注损伤后大鼠的肢体运动功能发生改变,针刺可以促进肢体功能恢复;(2)脑缺损伤区可见PCNA阳性细胞,存在细胞再生现象,针刺可以增强损伤区PCNA的表达,有利于损伤的修复和功能重建;(3)针刺组和模型组14d时缺血损伤区PCNA阳性细胞百分比低于7d组,随着损伤逐渐得到修复,细胞增殖现象减弱;(4)脑缺血损伤区可见VEGF阳性细胞,存在内皮型细胞再生现象,针刺可以增强损伤区VEGF的表达,有利于脑损伤后保护和缺血区血管再生;(5)针刺组和模型组14d时缺血损伤区VEGF阳性细胞百分比低于7d组,随着缺血损伤的修复,缺血缺氧状态得到改善,产生的VEGF减少;(6)由于脑损伤区同时出现PCNA阳性细胞和VEGF阳性细胞,前者是增殖细胞的标志,后者是促进血管再生的重要因子,可以推断,脑缺血再灌注损伤后脑内存在血管再生现象,针刺可以促进损伤区的血管再生,更迅速而充分的恢复损伤区的血供,促进脑损伤区的修复;(7)抑制剂针刺组脑损伤区VEGF阳性细胞百分比与针刺组相比有不同程度的降低,说明针刺促进缺血损伤区VEGF表达部分依赖eNOS的存在。

Results:(1)Increased expression of ICAM-1 appeared in cultured endothelial cells after anoxia and enhanced after reoxygenation.

结果:(1)体外培养的内皮细胞缺氧后ICAM-1表达上调,随复氧时间的延长ICAM-1呈增强趋势。

METHODS The organ-bath was used to observe the tension changes in rings of coronary and femoral arteries to different concentrations of isoprenaline ISO after endothelium removal, nitric-oxide synthase NOS inhibition by L-NMMA and β1 andor β2 adrenoceptor antagonization.

利用器官组织浴血管环法观察冠状动脉和股动脉在给予不同浓度的异丙肾上腺素ISO后血管张力的变化,以及去除血管内皮,一氧化氮合成酶NOS抑制,β1和或β2受体阻断后对其的影响。

RESULTS Endothelium removal, NOS inhibition,β2 adrenoceptor antagonization did not change the vasorelaxation induced by ISO in coronary artery, however, abolished the vasorelaxation in femoral artery.

结果 无论冠状动脉或股动脉ISO均产生浓度依赖的血管舒张。去除内皮, NOS抑制,β2受体阻断不影响ISO产生的冠状动脉血管舒张,而完全消除了股动脉的血管舒张。

Objective To explore the effect of anthocyanin on matrix metalloproteinases expression and activity.

目的 研究花青素对人脐静脉内皮细胞基质金属蛋白酶1,2和9蛋白表达和活性的影响。

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