内皮

Objective To investigate the antiangiogenesis effect of arsenic trioxide on human umbilical vein endothelial cell.

目的 以人脐静脉内皮细胞作为血管新生内皮细胞的模拟物，通过研究As2O3对人脐静脉内皮细胞的影响，探讨As2O3的抗血管新生作用机制。

Therefore, the purposes of this paper are on, firstly, the possible difference of secret of vasoactive substances from pulmonary artery and aortic artery endothelial cells; secondly, the regulatory effect of pulmonary microartery endothelial cella on the movement of pulmonary artery.

所以本文的研究目的为：1研究肺动脉内皮细胞和主动脉内皮细胞分泌血管活性物质的可能差异：2研究肺微动脉内皮细胞对肺动脉血管运动的调节作用；此外，基于我室以往对吸烟和肺血管反应性的研究。

Tumor necrosis factor-alpha may injure vascular endothelial cells by many ways, and the injury of vascular endothelial cella can accelerate the release of tumor necrosis factor-alpha, which can injure the vascular endothelial cells again.

肿瘤坏死因子α可通过多种途径损伤血管内皮细胞，血管内皮细胞的损伤又促使肿瘤坏死因子α的释放，再次损伤血管内皮细胞，两者互为因果，形成恶性循环。

Part Two: The effect of fruit extract on CRL-2606 production of PGE2 Effect of anthocyanin rich fruit extracts on endothelial cells'PGE2 production Epidemical experiment shows that phenolics in fruits and vegetables may prevent the occurrence of chronicle cardiovascular heart disease. To investigate the activity of fruit extracts on artery blood vessel cells, we chose CRL-2606 cell line, a normal iliac artery endothelia cells. Using indomethacin as control, we investigate the effect of blueberry extracts, blackcurrant extracts, chokeberry extracts, cyanidin3-glucoside, and malvidin3-glucoside on the PGE2 production of CRL-2606 cells.

第二部分水果提取物对人体细胞系CRL-2606产生PGE2的影响水果提取物对血管内皮细胞释放PGE2的影响流行病学调查表明，蔬菜水果中的多酚类物质具有预防慢性心血管疾病的作用，为研究水果提取物对血管细胞的作用，我们选择回肠动脉内皮细胞CRL-2606细胞系作为研究对象，以indomethacin为对照，研究了blueberry，blackcurrant，chokeberry提取物及cyanidin3-glucoside，和malvidin3-glucoside对血管内皮细胞释放PGE2的影响。

As a result, the expression of EL mRNA was decreased too. There was a positive correlativity between them.

人脐静脉内皮细胞的增殖与人脐静脉内皮细胞内皮脂酶mRNA的表达呈正相关。

ResultsMacroscopic examination showed no excrescence,thrombus formation,arm fractures and corrosion.The devices were covered with collagen fibrosis and discrete endocardial cells,apparent inflammatory infiltration in the devices and around the devices 1 month after implantation.The implants were nearly endothelialized,while the inflammatory reaction relieved gradually,with myocardial cells ingrowth at the edges of the device 3 months after implantation.The devices were completely covered with endocardium and fibrous tissue.Moreover,endothelial cells could be found on the smooth microscrew adaptor.The inflammatory reaction diminished with a few chronic inflammatory cells existing.Neovascularization and lymphatic vessels ingrowth could be observed 6 months after implantation.

结果所有封堵装置表面均没有发现赘生物、血栓形成、支架发生断裂及被腐蚀；术后1个月，封堵装置表面被胶原纤维和散在内皮细胞所覆盖，大量炎症细胞浸润，封堵装置边缘有小灶性炎症细胞浸润；术后3个月，封堵装置表面几乎被内皮细胞所覆盖，炎症细胞较1个月时明显减少，封堵装置内见纤维化，封堵装置边缘心肌细胞浸入；术后6个月，封堵装置表面完全被心内膜和纤维组织所覆盖，伞尖表面光滑并有内皮细胞上爬，炎症反应明显消散，但仍有少量慢性炎症细胞存在，装置内有新生的血管、淋巴管长入。

Objective To investigate the alteration of vascular endothelial cells and circulation endothelial cells damage in acute-phase Patients with Coronary Heart DiseasConstruct technology platform of vascular endothelial cells damage, in order to provide new theory evidence and laboratory indicatrix of earlier-phase prophylaxis and diagnosis for nosogenesis、development、turnover of Coronary Heart Disease Methods 65 acute-phase Patients with Coronary Heart Disease of preparing for operation of heart...

目的探讨冠心病患者急性期血管内皮细胞、循环内皮细胞损伤的特点，构建检测内皮细胞损伤的技术平台，为冠心病的发生、发展、转归，甚至早期预防及诊断提供新的理论依据和实验室指标。

The present study analysis whether CRP could directly induce inflammation in endothelial cells, analysis what kind of effects CRP provide on cellular signal transduction in endothelial cell by gene array, and isolate LDL by one step of density gradient centrifugation, generate E-LDL by degrading LDL with multiple enzymes, direct fluorescent labeling CRP and LDL, investigate whether CRP play as intermediator in atherosclerosis.

本课题目的在于探讨CRP在脂质参与的动脉粥样硬化形成中是否起到介质作用，主要通过检测直接CRP能否诱导内皮细胞炎症表现，基因芯片分析CRP对内皮系统的细胞信号转导通路的影响，探讨CRP参与调控内皮系统炎症过程的主要机制，并且通过一步法密度梯度离心分离LDL，复合酶处理生成E-LDL，直接荧光标记CRP和LDL，分析CRP介导脂质紊乱尤其是LDL代谢产物参与动脉粥样硬化早期形成的作用。

We compared the spectral and its secondary structure of endostatin with and without of zinc, heparin and lanthanides. It demonstrated that the pH has strong effect on the interaction of endostatin and heparin.

研究了内皮抑素与锌离子、肝素、稀土离子作用后蛋白质的光谱学性质和二级结构的变化，首次发现偏酸性pH对肝素与内皮抑素的结合作用有特殊影响，为研究内皮抑素特异抑制肿瘤组织新生血管的生成提供了实验依据。

Objective: To investigate the possibility of pathologic scars treated in endostatin , by observing the effects of endothelial cell and neogenesis capillary of pathologic scars treated in endostatin , through establishing models of hyperplastic scar in rabbit ear and injecting Endostatin .

目的：建立兔耳增生性瘢痕的动物模型，并采用内皮抑素局部在体干预，观察其对病理性瘢痕新生毛细血管及血管内皮细胞的影响，以探讨内皮抑素防治病理性瘢痕的可行性。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。