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The mitochondria were highly bloated, accompany with disappeaance of the cristae and vacuolation of matrix.

未经光照的大鼠鼻粘膜VEGF、EGF和FGF主要表达在上皮和血管内皮;随着照射及其时间延长,上述三种因子蛋白在粘膜上皮和血管内皮表达明显增强。

In this experimental conditions, the VEC had not damnified obviously by perfusion with IECS in 4 hours. The pulmonary vascular resistance could decreased by POE1 and so vascular endolhelial cells would be protected. Mannitol not only increase osmotic pressure but also cleanse OFR. The addition of mannitol, POE1, glucose and osmotic pressure to IEC solution contributes to reduce the quantities of OFR.

2在本实验条件下所采用的IECS进行犬肺灌洗、离体保存4h之内肺血管内皮细胞无明显损伤,PGE;具有保护肺血管内皮细胞的作用;甘露醇具有增加渗透压和清除自由基的作用;灌洗前肺动脉内注射PGE;及增加 ECS渗透压和代谢底物、提高PH值使之略微偏碱均有助于抑制供体肺离体、低温、冷缺血保存期间OFR的产生。

93Nm respectively. There were three types of connection forms between endothelial cells including end-end (12.4%), overlapping (53.9%) and interdigitating (33.7%) junctions, the opening condition between endothelial cells was 1.1%.

内皮细胞间的连接方式有3种,即插入连接(33.7%)、重叠连接(53.9%)和端端连接(12.4%);处於开放状态的占1.1%;内皮细胞连接处有特殊连接装置的占53.9%。

Vascular endothelial growth factoris a new kind of blood vessel active factors was finded in recent years. It not only plays a very important role in the process of micrangium proliferation but also contributs to the stabilizing, maturating and refraining from apoptosis of nascent micrangium, it participates the vascular endothelial cell through specific binding with corresponding receptor.

血管内皮生长因子(vascular endothelial growth factor, VEGF)是近年来新发现的血管活性因子,通过与相应受体结合特异性的作用于血管内皮细胞,不仅在毛细血管增生中起着十分重要的作用,而且对于稳定新生的毛细血管,使之成熟,避免凋亡具有重要意义。

We have shown that folic acid normalizes endothelial function in children with type 1 diabetes who have a similar degree of endothelial dysfunction but, lower total homocyst ine and higher folate status.

我们以前研究显示患1 型糖尿病伴有血管血管内皮功能障碍的儿童,虽然补充叶酸可使受损的血管内皮功能恢复正常,但是导致较低的血浆总高半胱氨酸水平和较高的血清叶酸盐水平。

Fig. 3.Effect of endothelial cells on relaxation to ONOO- in precontracted rabbit pulmonary arterial rings by 10-6 mol/L PE in vitro.

内皮完整的 PARs相比,预收缩的去内皮PARs对ONOO-的舒张反应明显增强,舒张反应曲线明显左移。

Well you see that one month later there is a complete relining of the area that had no endothelium immediately after the denudation. An endothelium cell layer has regrown.

诸位可以看到,一个月后,刚剥落时没有内皮细胞的区域现在已完全被新生内皮细胞覆盖,重新生成内皮层。

To determine whether heparin could decrease VEGF concentration by sequestering VEGF in the endothelium, a fixed dose of recombinant VEGF was incubated for 40 minutes with EA.hy926 endothelial cells in vitro.

我们通过分离内皮细胞中的VEGF浓度来确定肝素是否能够降低VEGF浓度,剂量确定的重组VEGF与EA.hy926内皮细胞在体外培养40分钟。

RESULTS: Two subducting cDNA iibraries of up-reguiation and down-regulation differentially expressed genes in HUVECs after stimulated by endotoxin were constructed successfully. It was the basis for screening new endothelial cells to activate the related genes.

结果:成功构建了人脐静脉内皮细胞内毒素刺激后上调和下调差异表达基因两个消减cDNA文库,为进一步筛选新的内皮细胞活化相关基因打下基础。

VE-cadherin moved away from the transmigration site to different ends of it, whereas PECAM-1 opened to surround the periphery of a transmigrating PMN.

我们发现在PMN穿过内皮细胞层时,这两种连接体蛋白都不会突然消失,而是发生了渐进的相对移动--相邻内皮细胞间原本彼此接合的VE-cadherin会沿著细胞间的界线移向PMN两端;而PECAM-1的变化则是打开原本彼此间的键结,改而围绕在PMN周边。

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