内皮

Endothelin-1 (ET-1) is a potent vasoconstrictive peptide that was isolated initially from the conditioned medium of cultured endothelial cells. It is a pathogenic mediator with a number of deleterious effects, including vasoconstriction, fibrosis, vascular hypertrophy,and inflammation.Atrial natriuretic peptide, angiotensin II and nitric oxide also takes an important role in cardiovascular system.

内皮素-1(endothelia-1，ET-1)是一种由内皮细胞合成和分泌的、具有强烈收缩血管作用和促进细胞增生的血管活性多肽，心钠素(atrialnatriuretic peptide，ANP)、血管紧张素Ⅱ(angiotensin Ⅱ，AⅡ)、NO等在心血管系统功能的调节中也起着重要作用。

Methods Veinous blood was sampled for determination of markers of the fibrinolytic system and hypercoagulability at admission and on the 10th day in patients with acute coronary syndrome, including acute myocardial infarction in 15 and unstable angina pectoris in 20. An occlusion test to determine the maximal endothelial tPA release was performed in order to evaluate the endothelial tPA reserve capacity. 20 patients with stable angina pectoris and 12 normal subjects served as control.

35例ACS患者，其中急性心肌梗死15例和不稳定心绞痛20例，于入院当日和入院后第10天采集静脉血样以测定纤溶、凝血指标，以评价内皮tPA储备功能；同时做静脉闭塞试验以确定最大内皮tPA释放，并与稳定性心绞痛和正常人作对比。

In this study, human tongue cancer Tca8113 cells and human umbilical venular endothelial cell ECV304 are treated with CPT and the cell proliferation and apoptosis are detected in order to investigate the effect of CPT on Tca8113 and the mechanism of antiangiogenesis.

本研究以喜树碱作用于舌鳞癌细胞(Tca8113)及人脐静脉血管内皮细胞(ECV304)，检测细胞增殖及凋亡状况，以研究喜树碱对舌鳞癌细胞及血管内皮细胞的生长抑制和凋亡诱导作用，探讨喜树碱抗鳞癌的作用及可能机理，并初步探索其抗血管生成机制，为该药治疗皮肤肿瘤和银屑病奠定实验基础。

The significantly increase of ICAM-1 mRNA expression on alveolar epithelium and pulmonary venular endotheium was also found in asthmatic rats compared with those of normal and sensitized control, but the expression of ICAM-1 mRNA on pulmonary arteriolar endothelium and bronchial epithelium showed a inceasing tendency.

原位杂交结果表明，哮喘组大鼠肺静脉内皮细胞、肺泡上皮细胞ICAM-1 mRNA表达量明显多于对照组；支气管上皮细胞、肺动脉内皮细胞粘附分子表达也有增加的趋势。

The study ~s conducted to elucidate the mechanism by which the expression of adhesion molecules on human endothelial cells ~s up-regulatecL Methods Human endothelial cells derived fium umbilical venisQ-IUVEC were coincubated in viny whh native human sennn albtuiiin, HSA modified v~ith advanced glycation end products or RPMI-1640 culture medium. The expression of adhesion molecule intereellular adhesion molecule-l(7ICAM-l), vascular cell adhesion molecule-l and E-selectin was determined by irnrnunofluorescen staining and flow cytometer analysis.

分离正常人脐静脉内皮细胞，将晚期糖基化终产物修饰的人血清白蛋白、人血清白蛋白以及RPMI-1640完全培养基与HUVEC在体外共同培养，用荧光单克隆抗体染色，流式细胞仪定量检测内皮细胞表面细胞间粘附分子-1（ICAM-1）、血管细胞间粘附分子-1（VCAM-1）、E-选择素的表达。

Recombinant endostatin is a specific inhibitor of chick chorioallantoic membrane angiogenesis and human vitelline vein endothelial cell ECV-304 proliferation. The recombinant endostatin regressed established syngeneic B16 melanoma tumor in mice.

重组内皮抑素能够抑制鸡胚尿囊膜血管生成和人脐静脉内皮细胞ECV-304的增殖，在小鼠体内实验中对黑色素瘤产生良好的抑瘤效果（P＜0.01）。

This is a woundless, nonenzymatic method of obtaining highly purified primary endothelial cells of the rat aorta, especially practical for isolation and culture of small vascular endothelial cells.

此方法无损伤、不需要酶消化，能比较容易的获得高纯度大鼠原代主动脉内皮细胞，适用于细小血管内皮细胞的分离与培养。

Objevtive: To investigate the effect of effective parts of Zingiber officinal on the adhesion of ECV-304 cells with monocytes cultivated in vitro and on the expression of monocyte chemotactic protein-1 (MCP-1) and adhesion molecules.

中文摘要：目的：研究鲜姜有效部位对离体培养的血管内皮细胞与单核细胞的黏附力及对单核细胞趋化蛋白和黏附分子表达的影响，探讨其保护血管内皮细胞的作用机制。

The necrosis of avulsed flap was related to the type and extent of the damage of microvascular endothelial structure.

皮瓣坏死与微小血管内皮结构损伤的范围和类型有关，预测撕脱皮瓣活力最重要依据应是内皮的损伤程度。

VEGF can facilitate endothelial proliferation strongly and vasotropic growth with conjugating vascular endothelial cells specific receptor.

在众多的血管生成因子中，VEGF是最有力的血管生成因子，它通过和血管内皮细胞的特异性受体结合，具有强大的促内皮增殖、促血管生成作用。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新