内皮

Hepatic sinusoid capillarization plays an important role in occurrence of portal hypertension. The fenestra of endothelial cells in hepatic sinusoid reduces and the diameter of fenestra decreases. The formation of basement membrane impaires the substance exchange between blood and hepatic cells,which results in oxygen deficiency, metabolic product accumulation and cell necrosis.

肝窦毛细血管化在硫代乙酰胺诱导的肝硬化门脉高压发生中起重要作用，肝窦内皮细胞窗孔减少并减小，内皮细胞下基底膜形成使肝细胞与外界物质交换减少，导致细胞缺氧、代谢产物聚集，肝细胞坏死，最终导致门脉高压的发生。

The mechanism probably is that Pishang can inhibit the growth, movement and adheresion to extracellular matrix and endothelial cell of liver tumor cells, up-regulate the expression of nm23, down-regulate the expression of CD44, MMP-2, and inhibit the tumor neovascular by supressing the vascular endothelial cell, down-regulating the expression of VEGF, damaging the primitive mesenchymal cells and inhibiting neovascular gemmation.

砒霜具有明显的抗肝癌细胞作用，并有一定的抗侵袭与转移作用，其机制可能与其能抑制肝癌细胞增殖、迁移、阻止肝癌细胞与细胞外基质和内皮细胞粘附、上调肿瘤转移抑制基因nm23表达、下调肿瘤侵袭分子CD44、MMP-2表达以及通过抑制内皮细胞增殖、下调VEGF表达、损伤间充质细胞、阻止新生血管芽生等途径从而抑制肿瘤新生血管形成有关。

Methods and results Using high-resolution ultrasound system, we measured the diameter of the brachial arteries at rest, during reactve hypermia and after sublingual glyceryl trinitrate (GTN, 400μg) in 58 subjects, consisted of 18 controls with normal blood presure, and 40 patients with EH.

本研究利用牛主动脉血管内皮细胞的实验模型，观察氨氯地平和苯那普利对ET-1 mRNA表达的影响。方法：制备5-10代牛主动脉血管内皮的细胞悬液。取生长融合、成片的细胞随机分成三组。

Vascular endothelial growth factor is a dimeric glycoprotein and widely expressed in neurons besides vascular endothelial cells in ...

血管内皮生长因子是一类糖蛋白，除在脑血管的内皮细胞上表达外，在神经细胞上也有表达。

ObjectivesThe aim of this study was to assess the influence of holothurian glycosaminoglycan on the adherence of thrombin-induced platelets to human umbilical vein endothelial cells in a flow chamber system.

海参糖胺聚糖抑制血小板—内皮细胞粘附及其机制的研究目的血小板-内皮细胞粘附在血栓形成，尤其在动脉血栓形成中占有举足轻重的地位。

The degradating and redistributing of ECM were migration of VSMC and vascular remodeling through inhibiting the production of PDGF-BB and the activation of MMPs so to prevent the vascular stenosis.⑤Orthotopic hybridism in situ: The expression of MMP-3 increased after operation, the tendency and intensity were parallel to the expression of NF-κB. Tongxinluo could decrease the expression of MMP-3 and NF-κB. The study showed that the producting and activating of MMP-3 were modulated by NF-κB. The inhibition to the producting and activating of MMp-3 of Tongxinluo was mediated by inhibiting the activating of NF-κB. Conclusion ①The rabbit vascular stenosis model could be established successfully by plain balloon damage, the operation process was easy, economical and practical.

①单纯球囊损伤可成功建立典型家兔血管狭窄模型，操作方法简单，经济实用；②以VSMC增殖、迁移为主的内膜增厚以及以ECM降解、合成与再分布所致的血管重构是导致受损血管狭窄的根本原因；③通心络能明显抑制VSMC的增殖、迁移和ECM降解、合成，阻止血管内膜增生和血管重构，防止受损血管狭窄；该作用可能与其减少和阻止PDGF-BB的产生和活性，以及抑制MMPs的表达和恢复MMPs/TIMPs平衡有关；④通心络能显著抑制球囊损伤后血管内膜增生和血管重构，可能与其保护血管内皮，改善内皮功能，增加血清NO含量有关；⑤通心络抑制内膜增生和血管重构，减轻受损血管狭窄，还可能是通过抑制NF-κB的活化途径而起作用的。

Vascular endothelial cell damage occurs in critically ill patients and blood lipid level decreases.

结论危重病患者血管内皮细胞受损，血脂水平下降，血脂值结合循环内皮细胞数可作为评估危重病严重程度的参考指标。

The ci group, control groups and part of ci group with the same level of blood pressure were subgroup by the result of questionnaire, correlation analysis was made between the amounts of blood markers and ill performance characteristics of tabp. results 40% ci patients were tabp.

对100例ci患者和107例无血液病和肿瘤的对照者进行a型行为评定量表测定，并同时对两组人员的血管内皮细胞损伤的血浆标志物内皮素和血栓调节蛋白含量进行测定；再根据a型行为问卷调查结果，分别对ci组和对照组患者，以及在同一血压水平的ci患者按照个体的行为特征进行分组，然后对其血浆标志物浓度进行相关分析。

Methods The 100 patients with CI and 107 control subjects without any blood disease or tumors were evaluated by applying the Chart of Typical Behaviors of TABP, meanwhile the endothelin and thrombomodulin contents in plasma of the patients were measured for the mark of the damage of blood vessel endothelium. The CI group, control groups and part of CI group with the same level of blood pressure were subgroup by the result of questionnaire, correlation analysis was made between the amounts of blood markers and ill performance characteristics of TABP.

对100例CI患者和107例无血液病和肿瘤的对照者进行A型行为评定量表测定，并同时对两组人员的血管内皮细胞损伤的血浆标志物内皮素和血栓调节蛋白含量进行测定；再根据A型行为问卷调查结果，分别对CI组和对照组患者，以及在同一血压水平的CI患者按照个体的行为特征进行分组，然后对其血浆标志物浓度进行相关分析。

Methods The 100 patients with CI and 107 control subjects without any blood disease or tumors were evaluated by applying the Chart of Typical Behaviors of TABP, meanwhile the endothelin and thrombomodulin contents in plasma of the patients were measured for the mark of the damage of blood vessel endothelium. The CI group, control groups and part of CI group with the same level of blood pressure were subgroup by the result of questionnaire, correlation analysis was made between the amounts of blood markers and ill performance characteristics of TABP. Results 40% CI patients were TABP.

对100例CI患者和107例无血液病和肿瘤的对照者进行A型行为评定量表测定，并同时对两组人员的血管内皮细胞损伤的血浆标志物内皮素和血栓调节蛋白含量进行测定；再根据A型行为问卷调查结果，分别对CI组和对照组患者，以及在同一血压水平的CI患者按照个体的行为特征进行分组，然后对其血浆标志物浓度进行相关分析。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新