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These results indicate that stimulative effect of substance P might be due to shortening of the time course of inexcitable state of the voltage-dependent Ca2〓 channel.

结果提示,P物质可能是通过缩短电压依赖性Ca〓通道的失活时程,使Ca〓内流增加以致胰岛素分泌增加。

The results suggest that Lot has effect of prolongation of APD and increase of Ca2+ influx and these are very important in contribution to its positive inotropic effect, which may be related to inhibition of phosphodiesterase Ⅲ.

Lot有延长APD和促钙内流作用,且在其正性肌力效应的产生中起着重要作用,而这些作用的产生与其抑制PDE Ⅲ有关。

During rat's intracerebral hemorrhage processes, Glu is over released and accumulated in hypothalamus and brain tissues surrounding hematoma, which could induce the opening of 〓 and 〓 ion channels, and evoke cellular-toxic edema. Meanwhile it may also evoke 〓 influx into neurons. It is this 〓 influx that may activate phosphase and proteinase, disrupt protein and cellular skeletons, and further aggravate neuronic damage.

大鼠脑出血过程中Glu在下丘脑及血肿周边脑组织的大量释放和积聚,通过其开放〓离子通道,造成细胞毒性水肿,使〓内流激活磷酸酶和蛋白酶,破坏蛋白质和细胞骨架,加重NC的损伤过程。

Suyu capsule can improve all the symptoms of the depression model mice and protect injury of hippocampal neurons in the depression model mice. The possible mechanism of action is to restrict Ca2+ ion overfreight.

苏郁胶囊能改善小鼠的抑郁样行为;保护抑郁模型小鼠海马神经元损伤,其可能与苏郁胶囊抑制海马神经细胞外Ca2+内流,阻止Ca2+超载相关。

A23187 and OA could parthenogenetically activate Urechis unicinctus oocytes and activate MAPK, indicating that the effect of fertilization on GVBD and activation of MAPK was mediated by rising in intracellular free calcium, and phosphorylation of some proteins was enough to activate the oocytes.

钙离子载体A23187和OA可以孤雌活化单环刺螠卵母细胞并激活MAPK。说明:①受精是通过钙离子的内流来激活卵母细胞并使MAPK活化的。②某些蛋白质的磷酸化状态对减数分裂是必要而且在一定程度上是充分的。

The change of motor thrust ,deflection angle of thrust line with scarfed angle was investigated.

应用有限体积法建立了三维守恒型N-S方程组的数值求解器,对某非轴对称斜切喷管内流场开展了数值模拟计算,研究了斜切角度变化时引起的发动机推力及推力线偏转角变化。

According to the classification and stage principles of folds, we divided the folds into three stages. The first periodic folds: the prime folds of the Indosinian orogenic cycle; the second periodic folds: the intrafolial theomorphic folds of Post Indosinian; the third periodic folds: the superposed folds of Himalayan to Yanshanian.

根据褶皱构造的分类、分期原则,首次将雅砻江锦屏水电站地区褶皱划分为3期:第1期为印支造山期主褶皱;第2期为印支期后层内流变褶皱,第3期为燕山期-喜山期叠加褶皱。

In the course of capacitation, the membrane potential might be depolarized resulting from K〓 or Na〓 influx.

获得精子由于阳离子内流和膜电位的去极化,Ca〓通道开放,此时Ca〓通道阻断剂使通道关闭。

Loss of these gradients depolarizes cell membranes, leading to the influx of calcium through voltage-gated calcium channels and triggering the release of neurotransmitters such as glutamate from presynaptic nerve terminals.

GLU与突触后神经元膜上的受体相结合,导致钠离子和钙离子内流,引起一系列的生物化学级联反应。

The transmission is conducted in the form of action potentials along the axon of DRG neuron to the presynaptic membrane in spinal dorsal horn. Action potential depolarizes the presynaptic membrane and activates the voltage-dependent Ca〓 channel. The influx of Ca〓 then triggers the release of neurotransmitter.

外界感觉信息以动作电位的形式沿DRG细胞轴突由外周传向DRG细胞在脊髓背角的突触前膜,导致细胞膜去极化,引起电压依赖性〓通道的开放,〓内流介导突触前膜神经递质的释放,从而完成感觉信息由外周向脊髓的传递。

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但我们并不在乎沙场中的显露。

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