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The results suggest that Smad4,one of the intracellular downstream molecules of TGF-β superfamily,and an inductive signal mediating epithelial-mesenchymal interaction,may regulate the differentiation of ameloblast and odontoblast cells,and modulate dentinogenesis and amelogenesis.

结论首次观察到Smad4信号分子在人牙胚发育过程中的表达,Smad4作为TGF-β超家族细胞内信号分子,可能参与上皮间充质的相互作用,同时也参与成釉细胞和成牙本质细胞的分化以及牙釉质和牙本质的形成。

OPN Immuno-electron microscopy show the gold markers in thecraniopharyngioma cell of the ameloblast type be located on the endoplasmicreticulum that the swollen oncocyte afterbirth strach, from endoplasmic reticulumcreation behind secrete the outside of the afterbirth; But didnt see the gold markers inthe craniopharyngioma cell of the squamous type.

OPN免疫电镜显示成釉细胞型颅咽管瘤中金标OPN颗粒的产生位于肿瘤细胞胞浆的内质网上,由内质网产生后分泌到胞外;而在鳞状细胞型颅咽管瘤细胞中未见金标OPN颗粒,少量可见颗粒仅见于肿瘤间质中的血管内皮细胞上。

Methods:(1) Fura-2 based calcium imaging technique was used to examinate the effects of leptin on the basal [Ca2+]i, and the modulation effects of leptin on KCl-evoked [Ca2+]i increase in long-term cultured hypothalamic neurons.

对四个培养时间段的下丘脑神经元分别进行以下实验:(1)采用荧光钙离子成像技术,研究瘦素对细胞内静息钙离子浓度的影响,及其对25 mM KCl引起的细胞内钙升高的调节作用。

Leyalancy has become the famous brin the skin protection products in European US markets since its naissanceit is popular among the rich super stars.Besides thatthe royal people in European countries Japan are all fond of its extravagancy effectiveness.From then onLeyalancy shows its charm to the whole worldAt presentit is fashionable in about 28countries districts.It is the real name of royal skin protection products.

丽雅兰姬"三肽修复系列产品"不仅能在人体表皮层发挥快速成膜的祛皱效果,而且由内而外修复敏感肌肤及病变色斑肌肤,修复真皮层断裂,加速表皮再生,促进人体皮肤Ⅰ型胶原蛋白的大量生成高达350%有效祛除任何皱纹,同时激活弹力组织母细胞的形成,促使表皮细胞再生,提高肌肤弹性,让母细胞拥有足够的代氧量,由内而外祛除皱纹,淡化色斑及修复敏感肌肤。

The notable proliferation was not observed by eyes in the local of injection. The infiltration of inflammation cells and mild proliferation of fibrocyte around dura mater was observed by HE stained in 4 and 8 weeks after injection. Infiltration and exudation of inflammation cells was observed by HE stained in epidural nerve root. Compared with group A, no changes of group B, C and D were observed under specific stained. Proliferation of type Ⅱ collagen fibers around dura mater was seen under immunohistochemical stained in 4 and 8 weeks after injection. There is no significant demyelination changes under LFB stained. The thickness and shape of the myelin sheath in epidural nerve root was not regular under transmission electronic microscopy in 4 and 8 weeks after injection. Fibroblast was also seen there. In nerve endometrium, macrophage could be seen under TEM, myelinated nerve fiber changed significantly, but nonmyelinated nerve fiber changed mildly. When 8 weeks, the changes of group D is smaller than the group B and C.

给药局部肉眼观察未见明显的纤维组织增生;HE染色可见B、C、D三组给药后四周及八周时硬膜内外均有炎细胞浸润,纤维细胞轻度增生,硬膜外神经根内有炎细胞浸润及炎性渗出;特殊染色B、C、D三组同A组相比未见有脊髓及神经根的改变;免疫组化染色,给药后四周及八周时,硬膜内外均有Ⅱ型胶原纤维增生;固兰染色B、C、D三组未见有明显脱髓鞘改变,与A组相比无明显异常改变;电镜观察B、C、D三组在给药后的四周及八周时,表现为硬膜外神经根内髓鞘厚薄不一,形状不规则,可见成纤维细胞,神经内膜中可见有巨噬细胞;粗大的有髓神经纤维变化明显,无髓神经纤维受累较轻;八周时电镜下D组改变较B、C两组为轻。

The whole process is discontinous and can be thought of as finding the grid points on a specified region of the X-Y plane (Think of marking all integer interception points on a paper). Convert each grid point's X and Y coordinate to exponential values (like 2^x, 2^y) then we can use them as value of cost and gamme for cross validation.

这个过程是不连续的成长,所以可以想成我们在一个 X-Y 平面上指定的范围内找一群格子点(grid,如果你不太明白,想成方格纸或我们把平面上所有整数交点都打个点,就是那样),每个格子点的 X 跟 Y 经过换算(如 2^x, 2^y)就拿去当 cost 跟 gamma 的值来 cross validation。

In the course of reduction at about 1000℃,Fe_2O_3 and then Fe_3O_4 was almostcompletely transformed into Wüstite within a few minutes prior to the formationof metallic iron;but the reduction of Wüstite to metallic iron lasted a much lon-ger time.

在1000℃左右的还原过程中,在金属铁出现之前,在数分钟内Fe_2O_3和Fe_3O_4几乎都已全部还原成浮士体,但后者还原成金属铁的阶段,则须经历数十分钟之久,因此后一阶段便成为还原过程中控制的一步。

In the course of reduction at about 1000℃,Fe_2O_3 and then Fe_3O_4 was almostcompletely transformed into Wüstite within a few minutes prior to the formationof metallic iron;but the reduction of Wüstite to metallic iron lasted a much lon-ger time.Therefore the last stage reaction controls the whole reduction process.

在1000℃左右的还原过程中,在金属铁出现之前,在数分钟内Fe_2O_3和Fe_3O_4几乎都已全部还原成浮士体,但后者还原成金属铁的阶段,则须经历数十分钟之久,因此后一阶段便成为还原过程中控制的一步。

Brown aluminium oxide abra-Sive is electrically fusedin an arc-furnace from a mixture of bauxite, cokeas main raw ma-terials at high temperature. Its chemical composition contains Al2o3, TiO2, a small amount of SiO2,and Fe2o3, etc., micro-hardness: 18000-22000MPa, tou-ghess: higher than silicon carbide.

棕刚玉是以铝钒土、焦碳为主要原料,在电弧炉内经高温冶炼而成,主要化学成分为Al2O3TiO2还含有少量的SiO2和Fe2o3等,显微硬度Hv18000一22000,韧性比SiC高,用它制成的磨具,适于磨削抗张强度较高的金属,如各种通用钢材、各锻铸铁、硬青铜等。

Nationwide sampling program is designed according to the resources distribution and coal-forming periods as well as coal rank and yield of coal in China, 305 coal samples were collected and determined by catalytic spectrophotometry combined with pyrohydrolysis.The geochemical mechanism of the concentration or depletion of iodine was discussed during the process of coalification,which including peat diagenesis and coal metamorphism.The contents of iodine in Chinese coals fall in the range of 0.04-39.51 mg/kg.

根据中国煤炭资源分布和成煤时代,兼顾煤的变质程度和煤炭产量分布,在全国范围内采集了305个煤样,采用高温热水解—催化分光光度法分析了煤中碘的含量,探讨了煤化作用(包括泥炭成岩作用和煤变质作用)过程中煤中碘富集或亏损的地球化学机制。

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The objective is to subjugate and discourage the people, because that allows the elite to continue to rule unopposed.

其目的是压制和打击人民的积极性,因为这可以让实权派继续统治不会沦为反对派。

GOD,this is the second time you vanquished me!

天啊,这是第二次你打败了我!

So a kind of strong antagonism permeated in the relations of two countries.

所以两国这一时期的政治关系始终弥漫着一种强烈的对抗情绪。