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Appling proteomics,we can detect various of characteristic proteome,which induce intramolecular or extramolecular aggregation in α-crystallin and reduce its activity and accelerate the cataract formation.

白内障发生时,多种疾病特征性的蛋白质组改变,可导致α-晶体蛋白分子内或分子间的交联,分子伴侣活性下降,加速白内障的形成。

Cholesterol gallstones formed in C57L mice and fatty livers developed in AKR mice. Conclusions Biliary cholesterol hypersecretion is the key pathophysiological defect of gallstone formation, lith genes have effects on biliary cholesterol hypersecretion and susceptibility to cholesterol gallstone formation in C57L mice. Lithogenic bile is formed at the canalicular membrane and precedes the development of cholesterol gallstones. It is most likely that cholesterol and bile acid hyposecretion make the AKR strain susceptible to the development of fatty livers and resistant to gallstone formation.

结论胆道胆固醇的高分泌是胆囊胆固醇结石形成的主要病理生理基础,结石基因决定了C57L鼠肝内胆汁中胆固醇的高分泌和胆囊胆固醇结石的易患性,成石胆汁形成在肝内胆管,先于胆囊结石的形成;肝内胆汁中胆固醇和胆酸的低分泌可能与AKR鼠脂肪肝的发生和胆囊结石的免患性有关。

Gray matter damage was assessed on the basis of the number of normal neurons in the ventral horn. White matter damage was assessed on the basis of the extent of vacuolation and amyloid precursor protein immunoreactivity in the ventral and ventrolateral white matter.

根据腹角内正常神经元的数目评估灰质损伤程度,而白质损伤则根据空泡形成的程度以及腹内和腹外侧白质的淀粉样前质蛋白免疫原性来评估。

Namely, the fluid of swift water and tiny whirlpool come from kinetics of the process which make the mass transfer better; 2 Increase alkalinity to improve the capability of abirritation of the system and an optimal pH condition which fit to acidic bacterium come into being.

即通过动力学措施造成反应器内流体介质的湍动及形成微涡旋,利用涡流扩散和对流扩散来加速传质;2提高所处理的碱度,增强系统的缓冲能力,控制酸化菌生存的最佳pH值范围,以实现系统在酸化段有机去除能力的高效性。

The antifreezing property of the green concrete is mainly determined by the quantitative ratio between the number of independent cavities formed during the hydration process and the quantity of freezable ...

混凝土早期抗冻性能主要取决于水泥水化过程中在水泥石中所形成的独立空孔与受冻时体系内可冻水量之间的数量关系,并归纳出一系列提高混凝土早期抗冻性的规律及措施。

The active form of NGF is a dimer in which two monomer is linked by 3 disulphide bonds. This form of dimer makes the purification of NGF difficulty because the protein expressed in E.

在蛋白纯化过程中这种由二硫键形成的空间结构往往是蛋白纯化过程中复性的难点,尤其是在大肠杆菌表达生物蛋白时,所表达的蛋白往往以无活性的单体形式存在于细胞内。

The intramolecular hydrogen bonding can extend the ligand planarity and increase the intercalative ability of the complex to DNA. It is concluded that the torsion between the aromatic rings of ligands, due to introduction of the bulky substituent, results in the complexes only to partially or non-classically intercalate into DNA.

能够使配体平面性增大的分子内氢键的形成,有利于配体对DNA的插入作用;但是,由大体积的取代基所引起的配体芳环间的扭转,致使配体只能&部分地&或&非经典地&插入DNA碱基对。

Aimed at the complexity of fluvial strata, such measures as well cyclical comparison, step control and geological analysis of reference beds have been applied. Moreover the paper has developed a set of methods the techniques to extract the parameters controlling the formation of intra-sandbody thin interbeds. The present study has examined how thin interbeds affect the frame property and heterogeneity of individual sandbodies; revealed the permeability space distribution mode of meandering distributary channel's single side lithosomic body and straight distributary channel's aggrading lithosomic body. Through applying the distributary channel sandbody structural unit classifying and identifying method achievement, some horizontal wells have been deployed to dig the residual oil in the top of hick pay zone in the xing8-9 area, which shows better effect after they have been put into production.

针对分流河流砂体沉积特点采用了旋回对比、分级控制、不同相带区别对待的单油层对比方法;利用取心井、对子井等资料研究形成了分流河道砂体内部结构单元的倾角、倾向、规模等参数的提取方法;搞清了内部结构单元对单一砂体内非均质性的控制作用,建立了分流平原相单一点坝侧积体及顺直型分流河道单一加积体层内渗透率分布模式及剩余油分布模式,应用分流河道砂体结构单元划分方法识别研究成果,在杏树岗油田杏八九区纯油区部署了水平井,投产后见到了较好的厚油层顶部剩余油挖潜效果。

Rabbit was immunized by the conjugated alginate-BSA (1.0mg/kg) for 40-days routine immunity method; ELISA method was used to examine the titration of anti-alginate serum; The first generation parotid acinar cells were chosen to divided five groups (group A :contrast, group B: BAS, group C: alginate, group D: anti-alginate serum, group E: alginate +anti-alginate serum), We examined the proliferation of each part by MTT method at four times (lh, 6h,12h and 24h); In the meanwhile, The growth and shape of parotid acinar cells were observed under phase contrast microscope and scanning electron microscope.16 of the immunized rabbits by alginate were divided equally into Al and Bl groups, 12 normal rabbits were divided equally into A2 and B2 groups as control groups, Each rabbit was affused by 0.3ml(40fil/ml)alginate though parotid duct once time two days.

将藻酸盐与BSA偶连形成具有较强免疫原性的Alginate-BSA交联物免疫兔,按抗原量1.0mg/kg接种于新西兰白兔皮内,间隔10d加强免疫1次,共加强4次后,利用间接ELISA法检测藻酸盐抗体效价:将原代培养的兔腮腺腺细胞按10~4个/ml接种到96孔板上,置入细胞培养箱继续培养3d,分为5组:A空白对照组、B牛血清白蛋白组、C藻酸盐组、D抗藻酸盐血清组和E抗藻酸盐血清+藻酸盐组,分别加入PBS、牛血清白蛋白、藻酸盐或新鲜抗藻酸盐血清继续培养,分别于1h、6h、12h和24h不同的时间点,取出96孔培养板,采用MTT法检测5组腮腺腺细胞增殖情况

The results of the study indicate:(1) the stress, strain and velocity fields as well as the uplift rates of the model are consistent essentially with those of the prototype in nature;(2) the major driving force for intraplate tectonic deformation in central-eastern Asia results mainly from the compression of the Indian plate;(3) the existence of the RSBs, such as those of Tarim, Alxa, Ordos and Sichuan basin, is one of the basic origins for the development of large-scale compressional basins and the table-like uplift of the Qinghai-Tibet plateau;(4) The netlike plastic-flow in the lower lithosphere is faster than the displacement in the upper layer, controlling the tectonic stress and deformation fields in the upper crust;(5) the weakness layer distributed discontinuously in the middle crust influences the level of difference between the stress directions in the lower lithosphere and those in the seismogenic layer.

研究结果表明:(1)模型中的应力场、应变场、位移速度场和地表隆升速率,与自然条件下的实际状况基本相符;(2)中东亚板内构造变形的驱动力源主要来自印度板块的推挤作用;(3)塔里木、阿拉善、鄂尔多斯、四川盆地等相对稳定块体的存在是促成大型压性盆地形成和青藏高原平台式隆升的基本原因之一;(4)岩石圈下层的网状塑性流动超前于上层,控制上层的构造应力场和变形场;(5)中部地壳的非连续分布软弱层影响上、下层之间应力方向的差异程度。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。