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In addition, SW480 and HCT116 cells were treated with deoxycholic acid for 15, 30, 45, 60, 90 and 120 minutes. It was found that the deoxycholic acid treated cells showed an elevation of ATP activity by 12.35 %, 20.08 %, 29.69 %, 33.56 %, 45.85 %, 54.32 %, respectively. While the HCT116 treated cells, showed an elevation of ATP activity by 3.69 %, 5.59 %, 8.52 %, 12.26 %, 16.52 %, 19.71%, respectively.From the experiments conducted using the cell lines described above, it was further confirmed that genes CYP7A1 (cytochrome P450, family 7, subfamily A, polypeptide 1), AKR1D1 (aldo-keto reductase family 1, member D1), ALDH1A1 (aldehyde dehydrogenase 1 family, member A1), BAAT (bile acid Coenzyme A: amino acid N-acyltransferase), ABCA1 (ATP-binding cassette, sub-family A, member 1), APOC3 (apolipoprotein C-III), LIPA, LIPE (lipase, hormone-sensitive), PTGER2 (prostaglandin E receptor 2) and PTGS2 (prostaglandin-endoperoxide synthase 2) were up-regulated.

此外,为了证实其脂肪代谢产物胆酸对细胞癌化的影响,亦使用SW480和HCT116细胞株,经由脱氧胆酸在15分钟、30分钟、45分钟、60分钟、90分钟和120分钟处理后,其细胞增生比率分别有12.35%,20.08%,29.69%,33.56%,45.85%和54.32%(p.05)以及3.69%,5.59%,8.52%,12.26%,16.52%和19.71%(p.05)上升情形,并从这些细胞株进一步证实CYP7A1(细胞色素P450-7A1)、AKR1D1(醇醛酮还原酶-1-D1)、ALDH1A1(醛脱氢酶-1-A1)、BAAT(胆酸辅酶A:氨基酸N-醯基转移酶)、ABCA1(三磷酸腺苷结合盒转运体A1)、APOC3、LIPA、LIPE(脂肪酶/激素敏感脂肪酶)、PTGER2(前列腺素E受体2)和PTGS2(前列腺素内过氧化物合成酶2)等基因表现皆有呈现向上调控的情形。

High-pressure acting on samples were produced by shock wave front converging in metallic ball. Destruction and metallograph of metallic ball after shock treatment were studied.

在该装置上,利用冲击波由金属球体表面向中心汇聚形成的高压,对样品进行了冲击处理;分析了回收的金属球体内、外破坏情况及金相组织变化。

This evolution has yielded a better understanding and ability to control fractures of the metaphysis and, in the distal femur, even intra-articular fractures.

这一进展还包括对处理干骺端骨折,股骨远端骨折,甚至是关节内骨折的更好的理解和能力。

METHODS From 1990, nine cases (11 sides) with traumatic metacarpophalangeal joint defect were treated by the autogenous cartilage transplantation of metatarsophalangeal joint followed by modified treatment. Appropriate biological mechanics was provided by internal fixation and collateral ligament repair.

1990 年以来,应用改良处理后的自体跖趾关节面软骨移植修复9 例11 侧掌指关节面,通过内固定、侧副韧带修复并提供适宜的生物力学和营养环境。

In my study, based on morphological and biological studies, 53 character transformation series of 23 species which stand for 23 genera of the Microgastrinae in China respectively and 2 species of Miracinae and Cardichilinae were selected. Through analysis of character polarity using the method of outgroup analysis, two and multiple character data matrixe were obtained. The data is analysed through PHYLIP(Phylogeny Inference Package, version 3.6) software based on the method of cladistics, the consensus cladograms was constructed at last.

本研究以分布在中国东洋区和古北区的小腹茧蜂亚科23个属的23个种作为内群,奇脉茧蜂亚科和折脉茧蜂亚科各一种作为外群,基于形态学和生物学分析建立了53个性状演系列,通过外群比较法,得到一个由二性状和多性状数据矩阵,再用phylip(系统发育推断软件3.6版)处理数据矩阵,最后得到合意树。

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An effective moistureproof method for high-value ammunition packaging was put forward according to the ammunition corrosion caused by moisture.

针对潮湿是造成弹药腐蚀的主要原因,采用有效的防潮控湿技术,即弹药预先进行除湿处理,再采用防潮屏蔽包装加干燥剂去湿的方法,使弹药处于有效的湿度控制的微环境中,即包装内的相对湿度控制在腐蚀临界点以下。

"Sharon, who studied with Stefan Askenase and Leonard Shure, is a musicianly artist who has cultivated a wealth of subtle colors in his tone, both through his touch and in the intricacies of pedaling required for this music"

&沙龙,从师于斯戴芬·阿斯柯内斯和理纳德·舒尔,是一位既善于通过弹奏又善于通过这部作品所需要的复杂的踏板处理来培育他的音调色彩丰富性的音乐艺术家。&

The purpose of storing dung underground is to provide food for the beetle larvae which, unlike the adult beetles, have strong, hardened mandibles and, with the aid of mutualistic cellulose-digesting bacteria in the gut, are capable of dealing with the plant fibres which constitute much of

它们与成虫不同,拥有强而有力硬化的颚,加上内脏中有互利共生可消化纤维素的细菌相助,因而有能力处理粪便内占大部分的植物纤维。

The restriction enzyme patterns for eight species of mycobacteria were studied.

对PCR扩增片段的酶切样品的预处理和CE条件进行了优化,获得了8种分枝杆菌DNA的限制性内切酶谱图。

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