内啡肽

Unilateral peripheral inoculation of recombinant ectors on the ibrissal pad territory resulted in an about ninefold increase in proenkephalin A mRNA leels in trigeminal ganglion ipsilateral to the infected side.

重组体载体在单侧末梢初级传入去极化范围内的培养，最终导致感染同侧的三叉神经节脑啡肽前体A 的mRNA水平增加约9倍。

In rats treated neonatally with monosodium glutamate the leu-enkephalin and norepinephrine contents in the brain and spinal cord did not change obviously, but the dopamine content of the telencephalon increased significantly, as compared with the control.

本工作分别采用新生期大鼠注射谷氨酸-钠损毁弓状核区及电刺激弓状核区的方法，观察对脑和脊髓内亮-脑啡肽、多巴胺和去甲肾上腺素含量的影响。

Then sacrificed the rats in every group to get cornu dorsale medullae spinalis and to make frozen section.The changes of orphanin receptor mRNA which was related with algesia in cornu dorsale medullae spinalis were observed by hybridization in situ.

各组动物处死后，取脊髓背角组织，冰冻切片，采用原位杂交的方法，观察各组脊髓背角Ⅰ～Ⅵ层内与痛觉相关孤啡肽受体mRNA的变化。

Enkephalins, as endogenous ligands for opioid receptors, play an important role in nociceptive modulation.

脑啡肽作为阿片受体的一种内源生配体，在痛觉调节中发挥重要作用。

Methods］Systemic injection of KA results in forming animal model of epileptic susceptibility, at the same time, treated them with SVHRP,observed the epileptic behavioral processes according Racine seizure stage, and investigated the expression of PENK mRNA by means of RT-PCR.

方法］大鼠颈部皮下注射红藻氨酸，制备癫痫敏感性动物模型后，给予蝎毒耐热蛋白（scorpion venom heat resistant protein，SVHRP）进行干预。通过观察癫痫行为学表现检测SVHRP对癫痫敏感性形成的影响，同时应用RT-PCR技术检测不同处理组大鼠海马内前脑啡肽原表达的变化。

These findings suggest that NC (13-17) may play important roles in pain modulation at supraspinal level in mice and elicits these effects through a novel mechanism independent of the NC receptor and the traditional opioid receptors The bioactivity study of NC related peptide-NST showed that: NST could dose-dependently reverse the effects of NC in antagonizing EMs-induced analgesia; NST itself could increase the MAP and HVBR of rat, and the tension of rabbit isolated aorta muscle strips.

对孤啡肽相关肽—NST的生理活性研究发现，NST可以剂量依赖的拮抗NC对抗内吗啡肽-1和内吗啡肽-2的镇痛作用；NST对NC的降低大鼠平均动脉压作用无显著影响，但其本身可以升高大鼠的平均动脉压，后肢灌流压和离体血管条的张力，在心血管系统方面是一个新的生物活性肽。

The effect of intrahippocampal microinjection of enkephalin on cellular immune function and hippocampal IL-1α gene expression was studied in rats.

本文研究了海马内微量注射脑啡肽对大鼠细胞免疫功能及海马内白细胞介素－1α（IL－1α）基因表达的影响。

Here we demonstrate that [D-Ala(2)-MePhe(4)-Gly(5)-ol] enkephalin can facilitate the ability of morphine to stimulate MOR endocytosis.

在此，我们证明了[D-Ala(2)-MePhe(4)-Gly(5)-ol]脑啡肽可以促进吗啡的作用，激发MOR内噬作用。

The effect of intrahippocampal m.icroinjection of enkephalin on cellular immune function and hippocampal 1L- 1 u gene expression was studied in rats.

文研究了海马内微量注射脑啡肽对大鼠细胞免疫功能及海马内白细胞介素一la基因表达的影响。

The results showed that:(1)The proliferation activity of splenie lymphocytes stimulated by Con A was significantly increased with microinjection of Leu一enkephalin I p1(18 mmol/L) or Met-enkephalin I ucl(18 mmol/L)into bilateral hippocampus,but was inhibited by Lipopolysaccharide 1 41(50 ng/ul).

结果发现：(1)双侧海马内微量注射甲硫一脑啡肽或亮一脑啡肽各1 u1 (18 mmol/L)能明显增强Con A刺激的脾淋巴细胞增殖活性，而双侧海马内微注射脂多糖各1 }t1 (50 ng/PI)则起抑制作用。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。