内分泌

Regulation of follicular development and atresia is a complicated process,including the interaction of endocrine factors,ovarial regulatory factor and nutritional factors during the controlling of the ovocyte fate.

卵泡发育和闭锁的调节是一个复杂的过程，包括内分泌因素、卵巢内调节因子及营养因素在控制卵母细胞的命运中的相互作用。

the morphologic and hormonal changes of the ovarium in the dehydroeplandrosterone-induced rat PCOS model were similar to those of the patients with PCOS,and the insulin resistance was observed. It was proved to be a ideal PCOS amimal model.Key words DHEA;PCOS; Animal model.

DHEA诱导SD幼年雌性大鼠PCOS动物模型卵巢病理改变及血内分泌改变与PCOS病人相似，并存在胰岛素抵抗现象，是较理想的PCOS模型。

Methods: To establish a rat model of pancreaticoduodenal transplantation with venacava endocrine drainage and enteric eccrine drainage. The recipient rats were introperitoneally injected with 15 mg/kg of proline dithiocarbamate in experiment group and with equal amount of normal saline in control group 30 minutes before transplantation.

建立大鼠腔静脉内分泌引流、肠道外分泌引流的动物模型，脯氨酸二硫代氨基甲酸酯组供体胰腺保存在ProDTC的UW液中，受体鼠于移植前30min腹腔注射ProDTC(15mg/kg)；对照组供体胰腺仅保存在UW液中，受体鼠腹腔注射等量生理盐水，分别于再灌注后第0、1、3、6、12、24h等时点，处死大鼠，取血后切取移植胰腺。

The model of chronic pancreatitis induced by oleic acid demonstrated extensive acinar degeneration and overt damage of islet. So, it is suitable for research work of pancreatogenic diabetes.

油酸诱导的慢性胰腺炎大鼠模型表现为外分泌腺体广泛退化，内分泌腺体继发损伤，适合进行胰源性糖尿病的研究。

These results suggest that the activate spleen-energy method can achieve appetitive purpose by not only affecting the gastrointestinal tract function in periphery, but also regulating the process of ingestion in brain. The basic research about ingestion indicate: one hand, after food enters the gastro-intestinal tract, the endocrine cell of the intestinal tract is activated and secrete many kinds of brains intestines peptide, the level of the brain intestines peptide in blood as the periphery signal spreads to the central nervous system regions that control digest and feeding behavior. On the other hand, it has been shown that dorsal parabranchial neurons, containing CCK-8S, extend fibers to the VMH and are involved in the inhibition of feeding .

关于摄食控制的基础研究表明，一方面食物进入胃肠道后，激活肠道的内分泌细胞，分泌多种脑肠肽如CCK-8S，这些脑肠肽在血中的水平作为外周信号可通过&肠—脑轴&传入中枢神经系统介导消化和摄食行为的部位，影响摄食中枢神经元的活动调节动物的摄食行为；另一方面中枢神经元可合成释放内源性的神经肽直接作用于摄食中枢神经元调节摄食，如中枢鳃旁体神经元的神经纤维就可延伸到达VMH，并且合成释放内源性的CCK-8S。

In the study, we established the animal model of diabetic ED successfully. Modern medical methods such as routine lightscopy, pathology, transmission electroscopy, scanning electroscopy, fluorospectrophotometer and radio-immunity were employed. From the aspects of pathomorphism, cellular supermicrostucture and neurocrine, we observed the mixture's effect on status of the whole animal model and penial erection, the fast plasma glucose, protein non-enzyme gycosylation, nitric oxide synthase , testosterone. In contrast with control groups, the mixture could apparently slow down the corpus cavernosum penial, vascular, neural pathologic progression of the diabetic rats and had a better result than diabetic pill, invigorating yang and restoring normal capsule and amino guanidine.

通过实验研究，成功建立了糖尿病性阴茎勃起功能障碍动物模型，利用常规光镜病理、透射电镜、扫描电镜、荧光分光光度计、放射免疫法等现代医学研究方法，从病理形态学、细胞超微结构、神经内分泌学等方面，观察了降糖起萎合剂对模型动物整体状态和阴茎勃起情况、空腹血糖水平、蛋白非酶糖基化、一氧化氮合酶、睾酮等实验指标的影响，与对照组比较提示降糖起萎合剂能明显延缓大鼠基于DM基础上的阴茎海绵体及血管、神经病变的病理进程，其疗效优于消渴丸、壮阳复春灵胶囊及氨基胍。

Purpose: To observe the effect of embedding thread at pishu(BL20) andshenshu(BL23)on estradiol(E2) as well as the effect of clinical pain of postmenopausalosteoporosis. In addition, to approach the endocrine control mechanism of embedding threadat pishu and shenshu in prevention and cure the postmenopausal osteoporosis.

目的：观察脾肾俞穴位埋线对绝经后骨质疏松患者血清雌二醇及临床疼痛症状的影响，探讨脾肾俞穴位埋线防治绝经后骨质疏松症的内分泌调控机制。

Objective : To investigate in endocringical and metabolic characteristics on polycystic ovary syndrome with/without obesity.

目的：探讨肥胖与肥胖型多囊卵巢综合征在生殖内分泌、糖脂代谢方面的差异。

The metabolic and endocrine sequelae of intrafacetal depot steroids have not been studied, but extrapolating from epidural steroid injections, one would expect suppression of the hypothalamic–pituitary–adrenal axis lasting up to 4 weeks depending on the depot steroid used, and impaired insulin sensitivity manifesting as elevated glucose levels for less than a week.251,252 Although rare, a host of infections have been reported after intraarticular injections including septic arthritis, epidural abscess, and meningitis.253–255 Case reports of spinal anesthesia and postdural puncture headache have also been published.256,257

小关节间隙类固醇滞留所产生的代谢和内分泌作用也未见研究，但是从硬膜外类固醇注射可以推知，依据使用量的不同，其抑制下丘脑-垂体-肾上腺轴的时间可以持续4周。很多报道显示关节内注射后可以发生感染，但发生率较少，包括脓毒性关节炎，硬膜外脓肿及脑膜炎。也可见关于脊髓麻痹及穿刺后疼痛的报道。

Our study showed that the exposure to PCBs/PCDFs in utero by the female Yucheng adolescents did not have remarkable effects on their pubescent and postpubescent development of reproductive and endocrine functions.

我们的研究显示油症少女虽在胚胎期暴露到多氯联苯/多氯夫喃，但此暴露对她们在青春、后青春期的性徵发育及内分泌功能的影响并不显著。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！