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RESULTS:After pinealectomized mice was irradiated WBI with 75 mGy X-rays,we found levels of plasma corticosterone increased obviously,and the effects of the proliferative reaction of splenocytes to ConA and spontaneous proliferation of thymocytes was found to be decrease. But injecting melatonin into pinealectomized mice or putting melatonin in the cultured cell,its immune functions might renew the enhancement.CONCLUSION:Melatonin of pineal gland might regulate the immunoenhancement induced by low dose radiation.MeSH Pineal body; Melatonin; Radiation; Corticosterone; Immunity,cellular

低剂量辐射(low dose radiation,LDR)全身照射(whole body irradiation,WBI)可引起免疫系统的兴奋效应,主要表现在以T淋巴细胞功能激活为主的细胞免疫和体液免疫功能的增强并可提高机体的抗瘤作用[4,5],在LDR诱发免疫功能增强的同时伴有下丘脑-垂体-肾上腺皮质系统功能下调等神经内分泌功能的改变,神经内分泌对免疫系统的调节可能是LDR免疫兴奋效应发生的必要条件,松果腺MLT与辐射免疫兴奋效应的关系值得研究。

These results indicate that the expression of PrRP in hypothalamus,pituitary body,oblongata and thyroid gland may not be affected by the period of growth,that PrRP in adrenal gland maybe involved in regulating neuroendocrine and stress, and that PrRP in ovaries maybe promote the form of luteal cells,and further regulate endocrine of generation.

这些结果提示:小鼠下丘脑、垂体、延髓和甲状腺PrRP mRNA可能不受周期的影响,表达比较稳定;肾上腺PrRP可能参与神经内分泌和应激调节过程;卵巢PrRP可能参与促进黄体细胞的生成,从而对生殖内分泌起到一定的调节作用。

Pituitary hypophysis is themostcomplex body oftheglands, hormones produced by the body andnotonly bone and thesofttissue growth, and can affect theotherendocrine glandsactivities.

脑垂体hypophysis是身体内最复杂的内分泌腺,所产生的激素不但与身体骨骼和软组织的生长有关,且可影响其它内分泌腺的活动。

Pituitary hypophysis isthemostcomplex body of theglands, hormones produced by the bodyandnotonly bone and the softtissue growth, and can affecttheotherendocrine glandsactivities.

脑垂体hypophysis是身体内最复杂的内分泌腺,所产生的激素不但与身体骨骼和软组织的生长有关,且可影响其它内分泌腺的活动。

Both benign and malignant endocrine neoplasms demonstrate some degree of cellular pleomorphism, so it is not easy to tell benign from malignant on histologic grounds alone.

无论是良性内分泌肿瘤还是恶性内分泌肿瘤都显示一定程度的细胞异型性,因此仅从组织学上很难区分肿瘤的良恶性。

The ultrastructural features of the 7 structurally different endocrine cell types and the rostral pars distalis, stellate cells are described and discussed, The results indicate that the various cell...

在电镜水平上对腺垂体七类内分泌细胞的超微结构和对前叶存在的一种非分泌细胞作描述和讨论。结果表明,同属罗非鱼内分泌腺细胞在腺垂体的分布和染色特征是相一致的。

A hormone secreted by the thymus that stimulates development of T cells.

内分泌腺的或由其分泌的激素的内分泌腺的或由其分泌的激素的,与其有关的

Polycystic ovary syndrome , one of the most common endocrine diseases affecting women of reproductive age, plays an important role in anovulatory infertility, with a prevalence of up to 5%~21%; The main clinical manifestations include irregular menstruation (amenorrhea or infrequent menstruation or dysfunctional uterine bleeding), infertility, hirsutism, obesity and acanthosis nigricans. Elevated serum LH levels and hyperandrogenism, insulin resistance with compensatory hyperinsulinemia are its endocrinological features. Polycystic ovary morphology is also a common feature in PCOS. With the advance researches, PCOS displays its complexity and essential trend.

多囊卵巢综合征(polycystic ovary syndrome,简称PCOS)是育龄期妇女最常见的内分泌紊乱性疾病之一,在不排卵性不孕中占主要地位,发病率约5%~21%;主要表现为月经异常、不孕、多毛、肥胖及黑棘皮征,以高雄激素血症、促性腺激素异常、高胰岛素血症及胰岛素抵抗等内分泌学特征,以双侧卵巢增大呈囊性改变并间质增生为病理形态学基础的多系统疾病。

Results: 1. The depression patients in neuroendocrine abnormity make up 59.4% of the total. 2. Correlation of clinical features and neuroendocrine diversity of depression patients.① Agitate symptom often existed in HPA axle abnormal group.② The weight diversity was not obvious suffered HPT axle abnormal depression frequently, Sleep disorder and anxiety often exist in HPT axle abnormal group.③ Elder women suffered HPG axle abnormal depression frequently, The symptom of somatic often exist in HPG axle abnormal group.④ Self-reproach and delay symptom often existed in the HPA axle and HPT axle abnormal group.⑤ The adolescent fuffered the normal neuroendocrine group, Patients of the normal neuroendocrine group were often combined with anhedonia.

结果显示:⒈抑郁症患者神经内分泌异常率达到 59.4%;⒉抑郁症患者临床特征与不同神经内分泌轴具有相关性以下几点值得注意;① HPA 轴异常组抑郁症患者多伴有激越症状;② HPT 轴异常组抑郁症患者体重改变不明显,多伴有睡眠障碍、迟纯症状和焦虑症状,常出现自杀观念;③ HPG 轴异常组抑郁症患者多发于年龄偏大的女性,躯体症状多明显;④ HPA 轴和 HPT 轴均异常组抑郁症患者多伴有体重减轻和明显自责和迟滞症状;⑤正常组抑郁症患者多发于青少年,快感缺失症状明显。

It makes the three systems or the inside of one of systems to contact together and coadjust, and forms the complicated immune-neuroendocrine network.

高血压的发病过程中往往表现出神经系统、内分泌系统和免疫系统所构成的复杂网络的功能紊乱,其间的信息联系即主要是通过神经肽、内分泌激素、细胞因子来完成的。

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