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All lungs from CCl4 group showed accumulation of large mononuclear macrophage-like cells within the lumen of numerous small muscular and nonmuscular pulmonary vessels.

对照组肺血管内无巨噬细胞聚集，CCl4组肺血管内大量巨噬细胞聚集，并且iNOS和HO-1蛋白表达均定位于PIM内。

Light microscope and transmission electron microscopy showed that SMMC-7721 cells induced by SAHA had undergone the restorational alteration in morphology and ultrastructure, which were different from those of nontreated cells but were similar to those of normal cells, and the changes were as follows: the cells turned to be flat and spread; the nucleo-cytoplasmic ratio lessened and nuclear shape became rather regular; the number of nucleolus reduced and its volume lessened; euchromatin increased while heterochromatin decreased in nucleus; in the cytoplasm, mitochondria grew in number with relatively consistent structure and well-developed mitochondria cristae; Golgi complex turned to be well-developed and typical; rough endoplasmic reticulum increased. Immunocytochemistry assay showed that the expression of AFP and PCNA were declined significantly. FCM analysis showed SAHA could arrest SMMC-7721 cells in G0/G1 phase, with an accumulation of the cells in G0/G1 phase while a decrease of cells in S phase. Semi-quantitative RT-PCR detection revealed that the expression of p21WAFl mRNA was upregulated remarkably in the cells treated with SAHA.

结果：倒置显微镜和透射电镜观察显示，经SAHA处理的细胞增殖速度显著减慢，细胞体积增大，细胞核较小，形状较为规则，核仁数量减少、体积变小，核内常染色质增多而异染色质减少，核质比例减小，细胞质内线粒体数量增多、线粒体嵴发达，高尔基体较为典型，粗糙型内质网增多，呈现出与正常上皮细胞相似的形态变化；MTT比色法测定结果显示不同浓度(2.5、5.0、7.5、10.0uM)SAHA对SMMC-7721细胞的增殖均有抑制作用，并有明显的剂量依赖和时间依赖关系；免疫细胞化学检测显示SAHA能显著降低PCNA和AFP在SMMC-7721细胞中的表达；流式细胞仪检测结果显示，SMMC-7721细胞经SAHA处理后，G0/G1期细胞明显增加，S期细胞则明显减少，细胞被阻滞于G0/G1期；RT-PCR检测结果表明，SAHA作用12h后SMMC-7721细胞中p21WAF1 mRNA的表达即有增加，24h后更为明显。

The appearances of nonvascular lesions were as the following : solitary, huge cystic lesions with wall and septa obvious enhancement were found in malignant enbryonal sarcoma; mixed density mass with necrotic cystic change and solid portion enhanced obviously in carcinosarcoma; intrahepatic huge low density, cystic changes, calcification and margin enhancement were found in leiomyosarcoma.

血管源性表现为肝内多发低密度灶，强化明显，非血管源性表现为肝内巨大单发囊性病灶，增强囊壁和分隔明显强化；癌肉瘤表现为混杂密度肿块伴有坏死囊变，增强实质部分强化；平滑肌肉瘤表现为肝内巨大低密度病灶，可伴有囊变及钙化，增强见边缘强化。

In the 29 Aroma material studied, the content of the material having important effect such as norambreinolide, octadecanoic lactone(1), octadecanoic lactone(2), octadecanoic, 8,15-labdanum-1-ol,8,12-external oxidative labdanum-14-en-2-ol(1), 8,12-external oxidative labdanum-14-en-2-ol(2), 8,13-external oxidative labdanum-14-en-13-one(1), 8,13-external oxidative labdanum-14-en-13-one(2) Dihydroactinidiolide, solanone, norsolanone have Significant increasing trend in the aging, the peak of the content of material appear in the 18~21 months in the aging process.

在所测定的29种香气物质中，对香料烟特征香气有重要影响的香味物质如降龙涎香内酯、硬尾内酯2种异构体、硬尾醛、8，15－赖百当醇、2种8，13外氧赖百当－14－烯－13醇异构体和2种8，13外氧赖百当－14－烯－13－酮异构体，二氢猕猴桃内酯、茄酮和降茄二酮等成分在陈化过程中有明显的增加，总的香气物质含量变化的高峰期出现在陈化18~21个月。

The aim of this study was to develop a novel amphiphilic functional block poly(ε-caprolactone) bearing ketone groups MPEG-b-P(OPD-co-CL. 2-oxepane-1, 5-dione was copolymerized with ε-caprolatone in which methoxy poly (MPEG, Mn=5 000) and stannous octoate were used as initiator and catalyst, respectively. The syntheses were conducted by bulk and solution polymerization. 1H NMR results showed that peak position and splitting of the polymers synthesized through solution polymerization were consistent with theoretical data, demonstrating the products were designed block copolymers. While in the bulk polymerization, polymer peak position was changed due to their high reaction temperature, suggesting their structural variation.

将带有羰基官能团的4-羰基己内酯和ε-己内酯分别在甲氧基聚乙二醇(MPEG，Mn=5 000)为引发剂，异辛酸亚锡为催化剂溶液和本体体系中开环聚合，合成了两亲性侧基带有羰基官能团的聚己内酯嵌段共聚物MPEG-b-P(OPD-co-CL.1H NMR结果表明采用溶液聚合法合成的聚合物各峰的峰位置和分裂情况与理论一致，证明了产物是实验所设计的嵌段共聚物，而采用本体聚合法合成的聚合物由于温度的影响，聚合物各峰的峰位置发生了变化，说明其结构发生了变化；差示扫描量热法分析结果表明随着OPD单体含量的增加，聚合物的熔点，玻璃化转变温度和熔融焓增加；热失重测试结果表明OPD单体的引入增加了聚合物的热敏感性。

My special thanks go to Richard Ables, Richard L. Burton III, Guillermo Castro, Charles Kolya Colt, Johan Edstrom, Jason Essington, Aaron Gallagher, Bennett Hiles, Nick Heudecker, Devin Jeanpierre, Shane Jonson, Heather Lang, Justin Lee, Joe Littlefeatherstein, Andrew Lombardi, Marzia Niccolai, Joseph Ottinger, Jeffrey Pepper, Pranav Prakash, Sverre Rabbelier, Tracy Snell, Craig Tataryn, Nestor Toro, Jason Whaley, and Grace Wong.

我特别要感谢理查德冷杉，理查德伯顿湖三，吉列卡斯特罗，查尔斯游子马驹，约翰Edstrom的，贾森埃辛顿，阿龙加拉格尔，贝内特海尔斯，尼克Heudecker，德文让皮埃尔，巴蒂尔琼森，希瑟郎，贾斯汀李乔Littlefeatherstein 安德鲁隆巴迪，马尔齐亚天极ChinaByte，约瑟夫奥廷若，杰弗里辣椒，Pranav普拉卡什，斯韦勒Rabbelier，特雷西斯内尔，克雷格Tataryn，内斯特红牛，贾森瓦莱和黄润。

In order to overcome the difficulty in estimating the ripple component on dc-side capacitor reference voltage, the modified control algorithm is proposed by ignoring the ripple component. Furthermore, the relation between control performance and damping coefficient is researched. In addition, the reasons of voltage source converter inner-loop control overmodulation are also analyzed. Based on the relation between control performance and VSC inner-loop input saturation, damping coefficient is adjusted on-line by fuzzy logic reasoning so that the trade-off between control accuracy and limitation of VSC inner-loop control overmodulation is solved preferably.

由于在线计算直流电容指令电压波动量十分困难，在控制方法的执行中忽略波动量的影响，简化了控制方法的实现；此外，该方法还研究了所注入的阻尼大小对控制效果的影响以及APF内层控制过调制产生的原因，针对无源性控制律跟踪精度的要求与内层控制过调制限幅条件间的矛盾，通过构造模糊逻辑推理环节实现阻尼系数的在线调整，在满足内层控制限幅条件下确保跟踪精度和补偿效果。

METHODS:(1)The bile-pancreatic ducts of rats were ligated,the catheters were inserted into right jugular vein and jejunum and the acute pancreatitis model was established.Forty pancreatitic rats were divided into four groups and were given simple parenteral nutrition(PN,n=10),early enteral nutrition(EEN,n=10), median enteral nutrition(MEN,n=10),and late enteral nutrition(LEN,n=10) respectively.

(1)结扎大鼠胆胰管，经右颈静脉及空肠插管建立大鼠急性胰腺炎营养支持模型。40只急性胰腺炎大鼠分别给予：单纯肠外营养(PN组，n=10)，早期肠内营养(EEN组，n=10)，中期肠内营养(MEN组，n=10)，晚期肠内营养(LEN组，n=10)。

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Later, under the untypical parasternal four-chamber view which can thoroughly display the ostium of coronary sinus, the catheter was promoted further to the ostium of coronary venous sinus. Then the echocardiography technician adjusted the transducer of TTE in order to thoroughly confirm the position of the catheter tip. After confirming the position of catheter tip in the coronary venous sinus, the operator inserted the catheter into the coronary venous sinus for 3～4 mm farther. It was noted that if resistance was encountered by operator, the operation must be stopped, which was the same as x-ray fluroscopy as image guiding. TTE guiding His bundle elactric cahteter、high right atrium electric cahteter and right ventricular electric catheter in site: It is difficult using TTE singly since there are too many crossroads in inferior venous.

本研究结果显示，(1)单独应用TTE作为影像学引导进行冠状窦电极导管置放的成功率为93.8％～96.7％，并且应用TTE作为影像学引导放置专用冠状窦电极导管和普通电极导管的成功率和放置时间在统计学上无显著差异；(2)TTE作为影像学引导，除过度肥胖患者外，可完全替代X线引导进行冠状窦电极导管置放，包括鞘管和扩张管的放置、指引导丝在静脉而非动脉内的证实均可由TTE完成引导，且较X线C型臂有一定优越性；(3)TTE结合普通X线胃肠透视机作为影像学导引，可顺利完成心内电生理检查时导管的安全到位，而不需昂贵的X线C型臂，可将心内电生理检查扩大到广大的基层医院；(4)TTE较X线更易和更早期发现介入治疗的并发症如急性心包填塞等，对并发症的防治甚至挽救病人的生命至为重要；(5)动物实验研究表明，TEE可引导射频导管消融术时大头电极导管成功到位。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。