其类似物

Reaction of 5'-O-p-methoxytrityl-thymidine with 1, 1'-carbonyl-diimidazole gave the 3'-O-carbonylimidazolide, which was condensed in high yield with 3'-O-protected thymidine to give a dithymidine carbonate. In the same way, we obtained the protected trithymidine dicarbonate. After deprotection, we obtained quantatively the trithymidine dicarbonate.By the same stratagy, we completed the synthesis of dithymidine sulfite.It was shown that allyl can be used as a good protection group for hydroxyl of ribose in the synthesis of oligonucleotides consisting in some unstable nucleotide analogues.

我们在第一部分工作的基础上，以烯丙基作为3'-OH的保护基合成了保护的三胸苷碳酸酯以及二胸苷亚硫酸酯，用我们所得的脱保护条件进行了脱保护研究，得到了三胸苷碳酸酯以及二胸苷亚硫酸酯，并研究了它们合成中的一些化学问题，结果表明：烯丙基能很好地运用于这两类寡核苷酸类似物的合成中，其脱保护条件为中性，不会影响碳酸酯键及亚硫酸酯键。

Toxicity and species difference are the other problems of CPTs. Homocamptothecins , a novel CPT analog which contain an expanded seven-membered β-hydroxylactone, have shown elevated antitumor activity and improved stability without species difference.

高喜树碱是近年来刚刚出现的一类CPT类似物，其特征是将α—羟基内酯环改造成七元的β—羟基内酯环，不仅活性明显提升，而且体内代谢稳定性也大大提高，并且不存在种属差异现象。

Originally limited to dialkylamino methylenation, the application of Mannich reaction has been expanded much further in recent years to a wide variety of monosubstituted amines, amine equivalents and amides. In addition, a variety of Aza-Mannich and Mannich-Michael methodologies have emerged.

最初该反应的应用范围仅局限于二烷基胺亚甲基化反应，近年来才得到了长足的发展，其研究范围扩展到单取代的胺、胺的类似物以及酰胺等化合物，并发展形成Aza-Mannich和Mannich-Michael等复合Mannich反应。

A series of compounds Bl-B7 have been synthesized as the analogues of Yuehchukene and Murrapanine, the alkaloids isolated from Murraya species.

合成了一系列九里香生物碱月橘烯碱和Murrapanine的类似物B1-B7，并对其进行了表征。

Objective: To examine whether somatostatin analogous have effect on Graves ophthalmopathy and to compare its effects with that of glucocorticoid.

目的：研究生长抑素类似物能否有效治疗Graves眼病，并比较其与糖皮质激素的疗效。

Large carnivorous Australian bird with the shrike-like habit of impaling prey on thorns.

大型食肉性澳大利亚鸟，有类似伯劳的习性，将其捕获物刺穿在树刺上。

The resulting polymers showed good thermal properties and excellent organosolubility even in common low boiling point solvents, such as acetone, chloroform and 1, 1, 2-trichloroethane, yielding a polymer solution with solid contents over 10wt%.

聚合物膜的紫外-可见光吸收阀值波长低于350nm，比线性类似物的（450nm）低许多，得益于超支化结构导致的酰亚胺环结构的疏松堆积，有利于以其为大分子骨架的光敏材料在365nm紫外工作波长的光刻。

On its possibilities it goes around practically all existing analogs programs for Windows.

就其可能性，这是不言而喻左右，几乎所有现有的类似物的程序适用於Windows 。

On its possibilities it goes around practically all existing analogs programs for Windows.

就其可能性，这是不言而喻左右，几乎所有现有的类似物的程序适用于Windows 。

On its possibilities it goes around practically all existing analogs programs for Windows.

就其可能性，它周围几乎所有现存的类似物节目窗。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。