其类似物

Embryonic germ cell lines were isolated and cloned from gonad,gonadal ridge,analogue or the surrounding tissues of 9.5～13.5 days postcoitum mouse fetuses.Primordial germ cells were co-cultured with mouse embryonic fibroblasts obtained from the same conceptus.

自交配后9.5～13.5 d小鼠胎儿生殖嵴/腺或其类似物及周围组织，采用与其同源胎儿成纤维细胞共培养的方式分离克隆到具小鼠ES细胞诸多特征的胚胎生殖细胞系。

Analogues of GLP-1 and Dipeptidy peptidase-Ⅳ inhibitors have a better prospect in the recent study.

其可被二肽基肽酶Ⅳ降解，半衰期极短，限制了其临床应用，目前研究GLP-1类似物及二肽基肽酶Ⅳ抑制剂有更好的应用前景。

It's has been reported that lactoquinomycin and frenolicin B, analogues of kalamycin, can inhibit AKT for the pyran naphthoquinone skeleton they have. We found that although kalamycin has pyran naphthoquinone skeleton, but did not suppress AKT and its downstream signal system, then we make a sytematic analysis on the in vitro anti-tumor effect and mechanism of kalamycin.

有报道其类似物lactoquinomycin和frenolicin B是肿瘤靶点AKT抑制剂，并由此推断吡喃萘醌骨架在AKT抑制过程中发挥主要作用，我们发现虽然卡拉霉素含有吡喃萘醌骨架，但是并不抑制AKT及其下游信号系统；继而对卡拉霉素的体外抗肿瘤作用及其机理进行了系统的分析。

It is similar in structure to αandβ-Asarone that are genetoxic to rat hepatocytes. Carpacin''s isomer, myristicin is not genetoxic to rat hepatocytes and can induce glutathion S-transferase activity that is reported to have effect in rat hepatocytes.

其类似物α与β-Asarone对鼠肝细胞具有基因毒性及其异构物myristicin对鼠肝细胞并无基因毒性，且可诱发出glutathion S-transferase等解毒酵素的活性。

This information supports a reasonable probability that all monogastric species eliminate the originally ingested substance, melamine, or its analogues, and not a metabolite.

此信息支持一个合理的概率，所有单胃物种消除原先摄取物质，三聚氰胺，或其类似物，而不是一个代谢物。

At the depigmentation assay, DH and EH show dose-dependently inhibitory activities against mushroom tyrosinase, and the IC50 is 5.697 and 5.256 mM, respectively, and show noncompetitively inhibitory modes in the present of tyrosine, but not DOPA. The control synthetic products, D and E, have no inhibitory effects on tyrosinase. Using tyrosinase activity staining in PAGE gels, both DH and EH show dose-dependently inhibitory pattern in the presence of tyrosine, while, EH also could suppress tyrosinase activity in the presence of DOPA.

而美白活性方面，以商品酪胺酸以商品酪胺酸酵素进行实验，当基质为酪胺酸时，发现DH与EH具浓度相关抑制效果，IC50分别为5.697与5.256 mM，且其相对於基质酪胺酸之抑制型态皆为非竞争型抑制，而其结构类似物之对照化合物D与E则不具此活性；但当基质为多巴时则皆不具此活性；利用原态PAGE电泳活性染色亦发现抑制酪胺酸酵素结果，但EH在基质为多巴时也能下降酪胺酸酵素活性。

Upon binding ATP or a nonhydrolyzable analog such as AMPPNP, RecA undergoes an allosteric transition into a high-affinity DNA-binding form. When RecA combines with dsDNA to form RecA-dsDNA nucleofiliment, it can unwind dsDNA and change the dsDNA structure.

在ATP或其类似物的辅助下，RecA可以直接与双股DNA结合而形成核丝，并将双股DNA加以解螺旋，并改变双股DNA的结构。

MethodsErgosterol was separated from Bulgaria inquinants and oxygenized ;its analogue 7-dehydrodesmosterol was also oxygenized. The antituberculous activity of oxygenized products were detected using MTT method.

方法从胶陀螺中分离得到麦角甾醇，对其氧化得到麦角甾醇过氧化物；并对麦角甾醇类似物7-脱氢胆甾醇进行氧化得7-脱氢胆甾醇过氧化物；用MTT法检测其氧化产物的抗结核活性。

There's also increasing interest in using vitamin D or its analogs to treat autoimmune disorders.

也有越来越大的兴趣使用维生素D或其类似物治疗自身免疫性疾病。

Our research included four parts: design and synthesis of amine oximes and other compounds as ligands, label them with 〓Tc〓, assessment of their biological activities in vitro and in vivo, and preparation of 〓 kit for clinic use.

研究工作主要包括合成作为配体的〓及其类似物，制备其〓Tc〓标记物，进行乏氧细胞实验和荷瘤动物实验，考察它们在肿瘤细胞中的吸收与体系乏氧的关系，以及在不同荷瘤动物模型中的放射性分布和显像情况。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失