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Methods The influence of DA on the electric activity of the pain-excited neuron in the caudate nucleus of normal rats or morphinistic rats was recorded after the sciatic nerve was noxiously stimulated.

在给予坐骨神经伤害性刺激后,记录中枢痛兴奋神经元的电活动,观察多巴胺对正常大鼠和吗啡成瘾大鼠中枢痛兴奋神经元电活动的影响。

MethodsIsolated uterus preparations of above animals were made according to the literature and its contractive effects to four different extracts of Phrynium capitatum Willd flower were observed and recorded with BL-410 experimental system for biological function; the EC50s of the extracts were determined and compared with it of Herba Leonuri fluid extract.

目的探讨棕叶花不同提取物对家兔、豚鼠、大鼠、小鼠离体子宫的兴奋作用。方法采用BL-410生物机能实验系统,观察棕叶花4种提取物对非孕或注射己烯雌酚后家兔、豚鼠、大鼠、小鼠离体子宫的兴奋作用,并用EC50与益母草流浸膏进行比较。

The synthetic and release of excitory amino acids are greatly increased after cerebral ischemia and the balance btween excitory amino acids and inhibitory acids are broken.

脑缺血性损伤时,脑内兴奋性氨基酸的合成、释放明显增加,兴奋性/抑制性氨基酸的动态平衡被打破。

Glutamate is the major excitatory neurotransmitter in the mammalian brain and key mediator of intracellular communication, plasticity, growth and differentiation. NMDA receptors is one kind of Glutamate receptors. The N-methyl-D-aspartate receptor is a heteromeric ligand-gated ion channel that interacts with multiple intracellular proteins by way of different subunits.

N-甲基-D-天门冬氨酸受体是一种门控离子通道复合物,作为兴奋性氨基酸受体之一,主要分布于大脑皮层、海马、纹状体等部位,是兴奋性氨基酸递质传递的重要基础,同时是维持中枢神经系统功能正常的关键因素。

Methods The toad ischiadic nerve was soaked in one of the three local anesthetics: procaine, lidocaine and bupivacaine. The excitability of the toad ischiadic nerve was studied to note the disappearance time of action potential.

分别用普鲁卡因、利多卡因和布比卡因整体浸泡蟾蜍坐骨神经干,分别测定它们对蟾蜍坐骨神经干兴奋性的影响以及兴奋性消失后再恢复的时间。

Results Intravenous 5-HT caused obvious exciting effect on spontaneous afferent discharge of subdiaphragmatic vagus nerve.

结论5-HT可能是作用于与迷走传入相关的5-HT3受体兴奋了膈下迷走传入神经自发放电;促胰液素可以增强5-HT对迷走神经传入自发放电的兴奋作用。

Our observation indicates that capsaicin as a nociceptive chemical irritant can selectively activate primary afferent C-fibers to release SP and Glu from their central terminals in the superficial dorsal horn. It seems that the release of SP and Glu acting on NK-1 and NMDA receptors results secondarily in the activation of dorsal horn neurons, transmitting nociceptive information to supraspinal structures.

以上结果表明辣椒素作为一种伤害性的刺激源,可选择性兴奋C类传入纤维,引起其分布于脊髓背角浅层内的末梢大量释放SP和Glu,通过相应受体兴奋背角伤害性感受神经元,包括上行脊-丘束投射神经元,将痛觉信息传递至脑。

It was concluded that ACh potentiated glutamate induced neuronal excitotoxicity by way of m-ACh-R to lower Glu threshold.

可见,脑缺血时,乙酰胆碱通过M型受体降低谷氨酸兴奋毒性的阈值而表现出加强谷氨酸的神经兴奋毒性作用。

The Brains of people anticipating a win at the roulette table appear to react much like those taking euphoria-inducing drugs.

在轮盘赌桌上期待着赢一把的赌徒们大脑极度兴奋,其状态就像是服了能够让人产生兴奋感的毒品一样。

Four years ago before the return leg of the European semi-final against Inter, Gattuso thanked fan Marco Siracusa for a letter of encouragement sent to the Rossoneri.

米兰— 加图索很兴奋,十分兴奋。4年前,在欧洲冠军联赛半决赛对国际的比赛前,加速索感谢了为米兰寄来一封鼓励信件的球迷Marco Siracusa。

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