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"In this trial, risperidone was safe and effective for the treatment of tantrums, aggression and self-injurious behaviors in children with autistic disorder," write Lawrence Scahill and colleagues from the Research Units on Pediatric Psychopharmacology Autism Network.

参加此次试验的101位儿童(82位男孩,19位女孩)的平均年龄为8.8+/-2.7岁,采用risperidone0.5-3.5 mg/日,持续8周治疗的患者中,兴奋性得分降低了56.9%,而安慰剂组降低了14.1%p 作者指出的研究限制包括,观察时间不够长,不能确认risperidone的最小有效剂量,以及研究的注意力集中在特定的行为问题上,而不是孤独症的核心症状。

GABA is resitent to the toxicity of the excitory amino acids because it can promote the conduct of Cl-, prevent the depolarization of the postsynaptic inhibition effectively and the open of Ca2+-gated channel, reduce the metabolic rate of the ischemic nurons.

GABA可以拮抗兴奋性氨基酸的毒性作用,它主要通过促进氯离子的传导,有效的阻断突触后去极化及电压依赖性Ca2+通道的开放,降低正常灌注/缺血性神经元的代谢率和氧的消耗,从而使神经元易耐受缺血性损伤[9]。

The results showed that the main pathogenic bacteria ledlocal cows to endometritis were streptococcus,the next,Escherichia coli,staphylococcus and pseudomonas aeruginosa.NFPL could quickly reduce thenumber of the bacteria in uterus,and strongerly inhibit these bacteria in vitro.NFPL could excit the uterus,which occurred in enlarging contractionamplitude.NFPL could lower abnormal high content of progesterone and raiseabnormal low oestradiol.

结果表明,引起本地奶牛子宫内膜炎的主要致病菌是链球菌,其次是大肠埃希氏杆菌,葡萄球菌,绿脓杆菌;新促孕液能能迅速减少病牛子宫内细菌的数量,在体外对这些细菌也有较强的抑制作用;新促孕液对兔子宫有明显的兴奋性作用,主要表现在收缩波幅的加大;新促孕液能降低病牛血清异常升高的孕酮含量,升高异常降低的雌二醇含量。

The purpose of this research is to discuss the probable mechanism of acupuncture treatment combined with pharmacotherapy regulating glutamatergic function and anti-free radical effect on the dementia rats due to hippocampal CA, lesions induced by quinolinic acid. So that the author can provide the clinical application of acupuncture treatment combined with pharmacotherapy with experimental evidences in treating Alzheimers disease.

本文的研究目的是探讨针药结合对喹啉酸(Quinolinic Acid,QA)损毁海马CA_1区所致痴呆大鼠模型的中枢兴奋性神经递质谷氨酸(glutamate,Glu)和抗氧化指标的影响及其对提高痴呆大鼠学习记忆能力的可能机理,为临床针药结合治疗阿尔茨海默氏病(Alzheimers disease,AD)提供实验依据。

Since amitriptyline inhibited Kv1.1 and Kv7.2/7.3channels only at toxicologically relevant plasma concentrations,our results suggest a role for these channels in the neuroexcitatoryside effects of amitriptyline.

因为阿密曲替林仅在产生毒理学的相关血药浓度制 Kv1.1和 Kv7.2/7.3通道,因此我们的研究表明了这些通道在阿密曲替林的神经兴奋性不良反应中起的作用。

Perceptual wind-up (increased pain perception to constant intensity sensory stimuli at frequencies 0.3 Hz) is used as a proxy for central sensitisation to inestigate pain syndromes where pain hypersensitiity is important.

在痛觉过敏重要的情况下,感觉兴奋性升级现象(痛觉增加至恒定的强度,感觉刺激的频率达0.3Hz)被用来作为中枢促感觉剂的表现形式,来研究疼痛症状。

Calcium, blood calcium decreased, the brain caused by increased nerve excitability plant, resulting in baby night waking, night terrors, night irritability, sleep; baby should be given calcium and vitamin D and more sun: A, calcium: elemental calcium daily 200-300mg (1) Composite Calcium Granule: 2-3 packets a day (each contains calcium 100mg)(2) the activity of calcium granules: 4-6 packets per day (calcium per tablet 50mg) B, fill D : daily 400-800IU (1) concentrated cod liver oil drops: 2-4 drops per day (2) vitamin D2 candy: the daily 400-800IU (3) vitamin D3 injections: once a month, 20-300000 IU attention these objects must be a doctor's prescription, prescribed application. C, to the sun to vitamin D, ultraviolet radiation to the skin 7 - dehydrocholesterol into vitamin D3, to help calcium absorption, could be a day outdoors on the sun for half an hour each afternoon. 3, bile is a yellow pigment bilirubin, was it yellow staining and faeces, after bilirubin by oxidation into biliverdin, thus making green manure, the manure discharge encountered in diapers in the air oxygen, so that oxidation of bilirubin biliverdin, so that the surface of green manure.

缺钙、血钙降低,引起大脑植物性神经兴奋性增高,导致孩子夜醒、夜惊、夜间烦躁不安,睡不安稳;应给孩子补钙和维生素D并多晒太阳:A、补钙:每日元素钙200-300mg(1)复合钙冲剂:每日2-3包(每包含钙100mg)(2)活性钙冲剂:每日4-6包(每片含钙50mg)B、补D:每日400-800IU(1)浓缩鱼肝油滴剂:每日2-4滴(2)维生素D2糖丸:每日400-800IU(3)维生素D3针剂:每月一次,20-30万IU注意上述物均须医生处方,遵医嘱应用。C、向太阳要维生素D,紫外线要将皮下7-脱氢胆固醇转变成维生素D3,帮助钙的吸收,可每天户外上下午各晒半小时。3、胆汁中胆红素是一种黄色色素,被它染色及粪便呈黄色,胆红素经氧化过后变为胆绿素,从而使粪便呈绿色,排出的粪便在尿布中遇到空气中的氧,胆红素使氧化成胆绿素,使粪便的表面呈绿色。

Many lines of physiological and pharmacological evidence show that AMPA receptor desensitization plays an important role in fast excitatory synaptic transmission by affecting transmission efficacy of individual synaptic bouton, integrative functions of neuron, and synapse plasticity.

大量的生理学和药理学证据表明,AMPA受体失敏在快速兴奋性突触传递过程中起着重要的作用,对单个突触的传递效率、经元的整合功能和突触的可塑性均有影响。

Students from the medium-violence exposure group were chosen for a pre-experiment. They were asked to watch o the two video games that included different levels of violence. Then their blood pressure and heart rate were taken and recorded. And finally they were demanded to comment on the features (like their interest, excitement and whether there was violence in the content and image) of the video games.D.

在中等暴力量接触组抽取16名学生进行预试验,采用平衡法顺序在实验室随机让他们观看攻击内容不同的两个网络游戏视频(反恐精英:坏孩子和跑跑卡丁车:海盗追皮蛋),检测血压和脉搏的变化情况,然后对所观看的网络游戏视频的特点进行评估(如游戏的趣味性、兴奋性、内容和画面是否暴力等)。D。

Objective To investigate whether tyrosine protein kinases Src and Fyn were involved in the phosphorylation of NR2A induced by cerebral ischemia followed by reperfusion. Methods Transient (15 min) brain ischemia was induced by the four-vessel occlusion in Sprague-Dawley rats. The antisense oligodeoxynucleotides of Src and Fyn were used to suppress the expression of Src and Fyn by intracerebroventricular infusion once a day for 3 days before ischemia.

近年来,最受人们关注的缺血性脑损伤机制是兴奋性氨基酸(excitatory amino acid, EAA)的神经毒性作用及神经元内钙超载触发的级联反应[1],其中NMDA受体的NR2亚基在缺血性脑损伤中起着非常重要的作用,在缺血/再灌注(ischemia/ reperfusion,I/R)过程中其蛋白表达、磷酸化水平均有改变。

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In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是,在否定句或疑问句里,这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷

Nusa lembongan : Bali's sister island, coral and sand beaches, crystal clear water, surfing.

Nusa Dua :豪华度假村,冲浪和潜水,沙滩,水晶般晶莹剔透的水,网络冲浪。