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Objective To observe the effect of electric stimulation on the excitability of sciatic nerve trunk in vitro.

目的 研究电刺激对坐骨神经干兴奋性的影响。

Objective: To observe the effects of FXKQY and QTY on CNS excitability.

目的:观察芳香开窍药和祛痰药对CNS兴奋性的影响。

Heart Rate Variability is a marker of performance of the excitability of Sympathetic Nervous System and Parasympathetic Nervous System.

心率变异性是反映交感神经系统和副交感神经系统兴奋性的敏感指标。

Potassium channels play a critical role in stabilization of membrane potential and regulation of cellular excitability.

钾离子通道具有稳定细胞膜电位和调节细胞兴奋性的重要作用。

the interhemispheric asymmetries of brain motor cortical excitability in patients with depressive disorder are opposite to the controls, and the left cortical excitability in patients have a evident decrease relative to normal subjects.

抑郁症患者的皮层兴奋性与正常对照存在差异,具体表现为抑郁症患者左、右两侧皮层兴奋性的不对称性与正常对照呈相反表现;抑郁症患者左侧大脑皮层的兴奋性明显降低。

This showed the activation of parasympathetic decreased.

说明打击乐有降低副交感神经兴奋性的作用。

Both MK-801, a specific antagonist of NMDA receptors, and chelerythrine, an inhibitor of protein kinase C, could down-regulate the phosphorylation of NR2A via inhibiting the activation of Src and PKC respectively.

结果提示通过共激活脑缺血中的GABA受体调节兴奋性和抑制性之间的动态平衡模式,能够抑制一种新的NMDAR/Src介导的信号扩增,'NMDAR-Ca2+→ PKC → Src → NMDAR-Ca2+'环路,而减弱兴奋性的NMDAR。

As the most important inhibitory neurotransmitters in the central nervous system, the concentration change of GABA plays a vital role in neuronal excitory changes and abnormal discharge.

GABA作为中枢神经系统最具代表性的抑制性神经递质,其浓度的变化在神经元兴奋性的改变、异常放电的过程中起着举足轻重的作用。

The extremities were titanic, and there was no response to touch stimulations.Our results suggested that Pentobarbital sodium inhibited neuronal firing through GABA_A receptors, therefore the local field potentials and neural firing rates were inhibited; Urethane acted on many kinds of receptors including inhibitory and excitory ones, so the local field potentials did not change significantly; however, because of the multiform receptors on the neurons, the changing of firing rates to different neurons were not the same; Ketamine mainly acted on the NMDA receptors, therefore the local field potentials and neural firing rates were enhanced, and most neural firing rates would be increased.

从这三种麻醉剂的底层作用机制来看,戊巴比妥钠通过作用于GABAA受体对神经细胞发挥抑制性作用,因此表现为场电位和神经元放电的降低;氨基甲酸乙酯同时作用于多种受体通道,既有兴奋性受体,也有抑制性受体,因此,对场电位的影响不大,但对单个神经元来说,每个神经细胞上的受体通道分布差异较大,因此,单个神经元的放电频率变化会有所不同;盐酸氯胺酮主要作用于兴奋性的NMDA受体,故整体场电位活性增加,多数神经元的放电频率也会有所升高。

Methods The toad ischiadic nerve was soaked in one of the three local anesthetics: procaine, lidocaine and bupivacaine. The excitability of the toad ischiadic nerve was studied to note the disappearance time of action potential.

分别用普鲁卡因、利多卡因和布比卡因整体浸泡蟾蜍坐骨神经干,分别测定它们对蟾蜍坐骨神经干兴奋性的影响以及兴奋性消失后再恢复的时间。

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