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Sigh of AA and analysis of syndrome maybe existed in AA AA rats presenced tacho and delayed hypersensitivity after administration, they had two swelling climaxes on the first and sixteenth day, ankle joint was notable (P.01), body weight was normal, by comparison with B group, difference had notable significance (P.05), had obvious dose-effect relationship as well.

结果 3.1 AA的体征与可能存在的证的分析与正常组相比,AA大鼠于给药后出现关节速发型和迟发型超敏反应,于造模后第1及16天有两个肿胀高峰。

The results of flow cytometry in normal, B27 single transgenic mice and B27/hβ〓m double transgenic mice were 0.63%, 7. 87% and 35. 87% respectively. B27 antigen was also expressed in the cell surface and cytoplasm of colon, skin, testis and eyes of the double transgenic mice by the detection of immunohistochemistry, which was evident on the cell surface. 8 double transgenic mice bearing high copy (7 males, 1 female) developed spontaneous alopecia, psoriasiform dermatosis, joint swelling and nail changes in the rear paw.

免疫组化检测可见转基因小鼠的结肠、皮肤、睾丸和眼睛组织的细胞膜和细胞浆均有B27抗原的存在,尤以细胞膜明显。21只B27/h〓转基因阳性鼠中有8只出现脱毛和皮肤的银屑病样改变,同时伴有后肢的关节肿胀和趾甲变化。8只小鼠均为高拷贝,其中雄性7只,雌性1只。

Objective: To observe the influence of the "Leifengshi-1" on the synovia of knee joints of the Collagen-Induced Arthritis rats.

目的:观察类风湿1号对胶原诱导的关节炎大鼠关节滑膜病变的影响。

The "leifengshi-1" suppress the vascularization. And this function is possibly realized by reducing the expression of necrosis factor alpha and cyclooxygenase-2 in the synovia.

类风湿1号具有抑制CIA大鼠关节滑膜新生血管生成的作用,该作用可能通过下调滑膜组织TNF-α和COX-2的表达来实现。

Objective: To study the effect of unilateral chew on temporomandibular joint.

目的 研究偏侧咀嚼对大鼠颞下颌关节(temporomandibular joint, TMJ)的影响。

2The histopathology of TMJ of PA rats showed pronounced proliferation of the synovium cells, some lytic collagenous fibers and degenerative chondrocytes in the condyles, and exudated protein and desquamating cells in the articular cavities with some fibrinous adhesions.

大鼠PA时,双侧TMJ均可见滑膜细胞显著增生;髁突表层胶元纤维松解,软骨细胞变性;关节腔可见蛋白渗出,细胞脱落,局部呈纤维性粘连。

Articular cartilage of femur head epiphyses was collected in 3,6,12,24,48 hours,5 days,2 and 4 weeks after the operation.Expression of iNOS and HSP70 were analyzed by immunohistochemical technique.

制作4周龄SD大鼠缺血再灌流及对照模型,每组各40只,于术后3、6、12、24、48h、5d、2、4周不同时点对股骨头骨骺关节软骨iNOS及HSP70进行免疫组织化学检测。

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