关节膜炎

Synovectomy with 153 Sm-citrate-HA is effective for treatment of chronic arthritis with depe ndence on the doses and deserves further study.

关节腔注射一定剂量的153Sm-citra te-HA对滑膜炎出现有利效果，可作为治疗慢性关节炎的一种方法，值得进一步研究。

Objective To explore the technique of arthroscopic treatment of diffused pigmented villonodular synovitis, and to evaluate its clinical results.

目的探讨采用关节镜技术治疗膝关节弥漫性色素沉着绒毛结节性滑膜炎的方法及其临床效果。

Rheumatoid arthritis is an inflammatory joint disease in which perpetuation of synovitis leads to bone and cartilage destruction.

类风湿关节炎是一种慢性炎性关节疾病，其滑膜炎的持续存在导致骨和软骨的破坏。

Results:US detected significantly more joints with synovitis than clinical examination did.

结果：与体格检查相比，超声检出滑膜炎的关节数更多？

Objective: To explore the treatment technique of pigmented villonodular synovitis of the knee under arthroscopy and evaluate its results.

目的： 探讨关节镜下诊治膝关节弥漫型色素沉着绒毛结节性滑膜炎的方法及疗效。

Differentiate between the presentation, diagnostic test results and treatment of transient synovitis and

区分出 膜炎与细菌性关节在表现诊断检查结果与处置上的差。

However, the relationship between skin temperature regulation over the area with trigger points and referred pain is still unknown. Therefore, to implement the use of infrared thermogram as a plausible tool for the clinical assessment of referred pain in MPS and treatment assessment, current study will propose a human experiment based on the thermo-changes in skin temperature for patient with MPS.

方法首先是将筋膜炎症候群与正常成人对照观察在颈椎做触诊矫正治疗前后二组受试者所侦测到的皮肤表面温度与视觉分析痛觉、颈部关节活动度、激痛点疼痛阀值等资料作前后比较分析其差异性。

Results:(1) FSN can inhibit secondary joints swelling and multi-arthritis evidently, improve the whole condition of rats; at the same time, it can also lighten the synovial inflammation and hyperplasia of lesion joints distinctly, and prevent the joint cartilage and bone from destruction; the collective efficiency of FSN is better than TWP.(2) FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th / Ts and Thl / Th2 cells balance in peripheral blood, restrain exorbitant TNF- a ? IL-1 produced by PM O , thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF- a mRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflamination and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue,reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage.Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.

结果：(1)FSN有明显的抗炎作用，可显著抑制AA大鼠足跖肿胀与多关节炎，改善大鼠的全身情况，同时明显减轻病变关节滑膜炎症与增生，防止关节软骨及骨质的破坏，其综合作用优于TWP；(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常，纠正外周血中T细胞亚群Th／Ts及Th1／Th2平衡紊乱，抑制大鼠PHφ过高的TNF-α、IL-1分泌，而发挥抗炎和免疫调节作用；(3)在病变关节局部，FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达，降低滑膜组织中NF-kB表达，并增加凋亡蛋白酶Caspase-3表达，从而抑制滑膜的炎症与增殖；(4)FSN还可下调滑膜组织中VEGF表达，减少血管新生，由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀；(5)FSN的上述作用皆呈现一定的量效依赖关系，高剂量组作用优于低剂量组。

FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th/Ts and Th1/Th2 cells balance in peripheral blood, restrain exorbitant TNF-α、IL-1 produced by PMφ, thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF-αmRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflammation and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue, reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage. Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.

结果：(1)FSN有明显的抗炎作用，可显著抑制AA大鼠足跖肿胀与多关节炎，改善大鼠的全身情况，同时明显减轻病变关节滑膜炎症与增生，防止关节软骨及骨质的破坏，其综合作用优于TWP；(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常，纠正外周血中T细胞亚群Th/Ts及Th1/Th2平衡紊乱，抑制大鼠PMφ过高的TNF-α、IL-1分泌，而发挥抗炎和免疫调节作用；(3)在病变关节局部，FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达，降低滑膜组织中NF-kB表达，并增加凋亡蛋白酶Caspase-3表达，从而抑制滑膜的炎症与增殖；(4)FSN还可下调滑膜组织中VEGF表达，减少血管新生，由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀；(5)FSN的上述作用皆呈现一定的量效依赖关系，高剂量组作用优于低剂量组。

Pigmented villonodular synovitis is a benign condition, probably inflammatory in nature, with proliferative change of synovium of joint, tendon sheaths or bursae.

色素沈著陆绒毛结状滑膜炎（Pigmented villonodular synovitis，以下简称PVS），是较不常见的良性关节疾病，不易诊断。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。