关节的

Based on the foundation of anatomizing the structure of robot, taking full advantage of parallel move performance of the double triangle boom of the rock-drilling robot ac-cording to the condition of the diversification of the boomend location brought by the change of each joint, integrating the knowledge of robot kinematics, an expert system is established to adopt the personate means, that is" the first toorientate the end, then to orientate the location "to realize the speediness orientation.

作者在分析凿岩机器人钻臂结构的基础上，利用钻臂的双三角支架的空间平移性能，根据各关节变化所引起的钻臂端部位姿的变化，综合机器人学中运动学知识，建立一个专家系统，采用拟人化的方案———"先定点，再定位姿"，解决凿岩臂的快速定位问题，以实现描述各关节位置的变量的快速逆运算。

The results suggest that drug synovectomy may be one mechanism about intra-articular corticosteroid therapy in TMD, and this therapy could lead to progressive degradation and destruction of the articular cartilage.

糖皮质激素通过药物性的滑膜切除是治疗TMD关节源性疼痛的一个可能的作用机制；②一次性的关节腔内注射治疗剂量的糖皮质激素可以导致软骨基质的丢失和软骨的破坏。

Then the cultivated chondrocytes were embedded in fibrin glue fused on spongy bone, covered with priosteal flap; the complex was used to repair the femoral trochlea osteochondral defect which size is 3mm × 4mm × 4mm made in rabbit knee joint.

在A组的每只兔子的一侧膝关节股骨滑车部人为造成3mm×4mm的骨软骨缺损，骨刀切除软骨下骨到髓腔渗血为止(厚约4mm)，压迫后FG止血；取髂骨骨块，并尽可能保留松质骨，取下的骨块用PBS反复清洗，以除去血细胞，将松质骨填充在骨缺损处，松质骨面朝向关节腔，高度与周边软骨下骨齐平，把骨膜片生发层朝向关节腔，用无创伤缝合线缝合在周边的软骨或滑膜组织上；向EP管中加入1/2悬液体积的FG主体胶溶液并混匀，再与主体胶等体积的催化剂溶液一同注射入骨膜与骨块密闭的腔隙中；同理处理另一侧膝关节。B组处理与A组相比只是不加入软骨细胞；C组造成骨软骨缺损，FG覆盖创面后单纯用骨膜修复缺损。

Therefore to study the molecule regulation mechanism of development and maturation of condylar cartilage in embryo, can not only discover the mechanism of its physiological rebuilding and restoration to set up the academic base for related treatment in clinic, but possiblely supply new treatment methods for trauma and destruction to articular cartilage. Histological and immunohistochemistry methods have been used to state the feature of development of the mandibular condylar cartilage, and molecule mechanism of its endochondral ossification.

目前对四肢关节软骨、生长板软骨的发生及再生修复的研究较为深入，而髁突软骨的发生、生理改建及再生修复机制的研究尚处于起步阶段，因此研究胚胎期髁突软骨发育及形成的分子调控机制，可望揭示其生理性改建及损伤修复的机制，为临床有关治疗奠定理论基础，并可能为关节软骨的损伤及破坏提供新的治疗手段。

Solves this symptom method to divide into the surgery and the non-surgery treats, the non-surgery treats for example the physical property treatment and the pharmacological treatment, the effect is not often good, the surgery treats may divide into the traditional surgery and micro creates the surgery two kinds, the traditional surgery method is in the lumbar vertebra fusion the pexia, although this method excised has created the lumbar vertebra narrow yellow ligament and the small surface joint, but the surgery time was long, the wound was big as well as although the lumbar vertebra fusion and fixed has removed the pathological change stage abnormal movement, but the neighbor stage's abnormal movement increased, between the awl in plate's pressure elevated obviously, the small articular process exceptionally drew back changes with the fixed stage bone quantityThe loss, causes the fixed stage vertical motion stage to draw back changes ASD[1], but new micro creates the surgery is opens a small wound in the back, and implants the interspinal to open, then solution lumbar vertebra narrow sickness question.

解决此种症状的方法分为手术及非手术治疗，非手术治疗例如物理性治疗和药物治疗，往往效果不佳，手术治疗又可分为传统手术和微创手术二种，传统手术方法就是腰椎融合内固定术，虽然此种方法切除了造成腰椎狭窄的黄韧带和小面关节，但手术时间长，伤口大以及腰椎的融合和固定虽去除了病变节段的异常活动，但邻近节段的异常活动增加，锥间盘内的压力明显升高，小关节突的异常退变和固定节段的骨量丢失，导致固定节段上下运动节段的退变ASD[1]，而新型的微创手术是在背部开一个小伤口，并植入棘突间撑开器，进而解决腰椎狭窄症的问题。

Methods A wet hip joint's sample from corpse was scaned by CT and all images of every cross-section hip joint's layer was obtained, and an hip joint's model was contructed with Unigraphics NX 2.0 and Solid Works 2006 SP 0.0 software. The models were assembled when simulated total hip arthroplasty after total hip joint prosthetic and ischiofemoral ligament model had been constructured. Analysis was done on von Mises stress distribution and amount of total hip component when simulated seated leg-crossing manuver. The bone and metal components were meshed as rigid bodies, composed of three-dimensional, all-quadrilateral rigid body elements, and hip joint capsule ligament was fully three-dimensional, hexahedral continuum elements representations. Results The current form of this ischiofemoral ligament's reconstruction finite element model provided for multi-body contact, large displacement interfacial sliding, large deformation capsule ligament representation, and clearly reflected the real ischiofemoral ligansent's anatomy and biomechanical behavior. The maximum on Mises stresses at the joint interface was more than that fur an otherwise identical hardware-only construct.

选择成人尸体髋关节行CT成像得到髋关节每层横截面图像，提取边界坐标，利用有限元分析软件Unigraphics NX 2.0和Solid-Works 2006 SP0.0构建出髋关节三维有限元模型及人工髋关节假体，并模拟全髋置换术进行装配，将坐股韧带按其术中重建位置进行构建骨骼与金属模型采用三维十节点四面体实体单元进行网格划分，关节囊六面体连接单元划分，模拟坐位腿交叉动作载荷获取假体撞击过程的角活动度和相应的von Mises应力分布情况结果所构建的多体连接、大界面划移、大变形的坐股韧带重建有限元模型，客观反映坐股韧带真实解剖形态及生物力学行为，增加坐股韧带重建的模型其关节面的最大主应力值大于仅有金属的模型。

Both Fas and NO can lead chondrocyte apoptosis respectively and cause articular cartilage destruction. IGF-Ⅰ, TGF-β, bFGF, BMP and other growth factors are polypeptide agents that can influence cell activity by signal convection. They can accelerate chondrocyte proliferation and proteoglycan synthesis, play the local regulation action on formation and plerosis of bone and cartilage tissue by autocrine or paracrine. They have the ability to induce cartilage formation. Some investigations showed that growth factors can influence chondrocyte metabolism, synthesis of specific Ⅱ type collagen and proteoglycan by co-operation and inhibition. 1. 3 Situation of OA therapeutics The therapeutic methods of OA mainly comprised non-drug treatment, drug treatment, operation treatment, tissue and genetic engineering, et al. Drug treatment is the chief method among them.

若其活性发生改变，则将导致关节软骨基质成分的丢失和进行性破坏；软骨细胞凋亡与OA的发病密切相关，Fas与NO可各自独立介导软骨细胞凋亡，造成关节软骨破坏；IGF-Ⅰ、TGF-β、bFGF、BMP等生长因子是一组通过细胞间信号传递影响细胞活动的多肽因子，具有促进细胞生长、增殖与合成等作用，可通过自分泌或旁分泌方式对骨和软骨的形成和修复起局部调节作用，可促进软骨细胞增殖、分化与蛋白多糖的合成，具有较强的诱导软骨形成的能力，研究表明多种生长因子相互促进、相互抑制，以协同或拮抗方式影响软骨细胞代谢，影响软骨细胞特异性Ⅱ型胶原和蛋白多糖的合成分泌。

The result showed that the treatment methods could not determine the changes in the joints, and the conservative approach should be the first choice for those not severely dislocated fractured condyles, but the follow-up must be done frequently and some advices must be given.

说明创伤引起的关节结构的变化不因治疗方式的改变而有明显差异，不管采用哪种治疗方式，都有可能不能避免关节疾病的发生，因此，我们认为对未发生严重的骨折移位或粉碎性骨折的患者应首选保守治疗法，但应严密随访观察，发现问题，及时处理。

Construct PLXRN-IL-1Ra and PLXRN-IL-10 vector, lapine synoviocytes were first transduced in culture by retroviral infection. The genetically modified synovial cells were then transplanted by intra-articular injection into the knee joints, assay of joint lavages confirmed that the gene expression was not lost after 14 days of transfer. Knees receiving the hIL-1Ra had significantly reduced cartilage breakdown. Delivery of the hIL-10 was less effective, When both genes were used together, there was a greater inhibition of cartilage breakdown and a considerable reduction of cartilage matrix degradation.

构建PLXRN-IL-1Ra、PLXRN-IL-10逆转录病毒载体，体外感染同种异体原代滑膜细胞，接着将转染了外源基因的滑膜细胞行关节腔注射入创伤性骨关节炎兔膝关节，通过对关节滑液的ELISA分析证明外源基因的表达在基因转移后14天还很稳定，只接受hIL-1Ra基因治疗的膝关节软骨损坏明显减轻，接受hIL-10基因治疗的膝关节治疗也有一定效果，当两种基因同时导入时，有非常明显的抑制软骨破坏和软骨基质降解的作用。

The most relevant to people suffering from joint pain is called Hyaline cartilage, which is the tough, smooth tissue that lines the surface of joints such as the knee, to provide an almost frictionless layer over the bony parts of the joint.

最为相关的人患有关节痛的是所谓的透明软骨，这是艰难的，流畅的组织，线的表面关节如膝，提供了几乎无摩擦层骨部分的联合。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐