关节的

Material and MethodsRA Rabbit Model group: 15 early RA rabbits of the same weight and variety Control group:10 normal rabbits of the same weight and varietyMethods of making RA rabbit model:elect 15 normal rabbits of the same weight and variety, dissolve Ovalbumin in 0.9% sodium chloride solution, to make the solution of 20mg/ml concengtration, blend the same quantity of complete Freund′s Adjuvant equably ,inject the mixed solution into endermic tissue of the rabbit′s scapular section, making the rabbits allergic, inject 1 ml of the mixed solution to one rabbit every time, inject 1 ml of the mixed solution in 5 different places of the rabbit′s scapular section, inject the rabbit one time every week,inject 3 weeks continuously,it turned out to be that the rabbits will be allergic, inject Ovalbumin blent with the 0.9% sodium chloride solution into the knee joint cavity of the rabbits in the fourth week, 5 mg Ovalbumin every knee joint cavity,two knees of every rabbit of the 15 rabbits are both injected,the arthrosis diameter and the exterior temperature of the knees will be added obviously in 24 hours,and they will drop gradually,at the time of the 14th or 21th day, the arthrosis diameter and the exterior temperature of the knees will get to the balance time,the incidence rate of RA is 100%.after the RA model succeeds,it is the early time of RA from the first week to the fourth week,after the fourth week,it is the late time of RA, the cartilage of the femoral condyle and the subchondral bone cortices will be changed unrecoverily.

资料与方法RA模型组：早期RA家兔模型15只，品种及体重接近。对照组：正常家兔10只，品种及体重接近。RA家兔模型制作方法：选取15只成年家兔，体重、品种接近，将卵蛋白溶解于生理盐水，配成浓度为20mg/ml的溶液，与等量完全弗氏佐剂混匀，注入家兔肩胛区皮下致敏，每只家兔每次注射1ml，于肩胛区5个不同区域注射，每周一次，连续注射3周而致敏，第4周向膝关节腔注射卵蛋白生理盐水溶液，每只关节腔注射5mg卵蛋白，15只家兔膝关节全部注射，24h内此关节直径和表面温度大幅度上升，以后缓慢下降，至14～21d达到平台期，发病率达100%。造模成功后第1～4周为早期改变，第4周以后出现不可逆的关节软骨及骨破坏。采用高频超声对RA模型组与对照组的膝关节髌上囊液体厚度、滑膜及股骨髁软骨厚度及软骨下骨皮质的回声情况进行对比观察。结果RA组模型组膝关节髌上囊积液及滑膜的厚度明显厚于对照组，其股骨髁软骨的厚度与对照组相比无明显差异，其软骨下骨皮质与对照组相比无明显改变。

There was apparent interspace between repaired tissue and surrounding normal tissues. The results indicated that: 1 Although autogenic cartilage obtained from patella in knee joint is limited, chondrocytes cultured in vitro could be regulated by some growth factors, therefore sufficieng and well-phenotype chondrocytes could be harvested to construct tissue engineering implants for transplantation. 2 It showed well therapeutic efficacy with the method of repair in our research.

实验结果表明：①自体膝关节髌骨来源的软骨虽有限，但在体外单层培养时应用生长因子对其进行调控，能为自体关节软骨缺损的移植治疗提供数量充足的、表型良好的软骨细胞以用于构建组织工程移植物；②本实验中所应用的修复方法治疗效果良好，能较有效地克服和解决目前在临床上所用的自体关节软骨细胞移植修复关节软骨缺损时所存在的软骨细胞容易丢失等问题。

The principles of the operative technique are to (1) restore coronoid stability throughfracture fixation (type-II or III fractures7) or through anterior capsular repair (a type-I fracture),(2) restore radial head stability through fracture fixation or replacement with a metal prosthesis,(3) restore lateral stability through repair of the lateral collateral ligament complex and associated so-called secondary constraints such as the common extensor origin and/or the posterolateral capsule,(4) repair the medial collateral ligament in patients with residual posterior instability, and (5) apply a hinged external fixator when conventional repair does not establish sufficient joint stability to allow early motion.

外科手术的原则是：①通过骨折固定(2型骨折或3型骨折)或者经前方关节囊修复(1型骨折)恢复冠状突的稳定。②通过骨折固定或假体置换恢复桡骨头的稳定性③通过修复侧副韧带以及相关的所谓的次要限制如伸肌群起点和后外侧关节囊。④残余的后侧不稳，修复内侧副韧带⑤当传统的修复方法不能建立有效的关节稳定以便允许早期活动时，可以应用外固定器。

Palpate for tenderness at the sternoclavicular joint, the acromioclavicular joint, the subacromial area...

对于胸骨锁骨处的关节，肩峰处的关节以及肩背处的关节这样敏感的部位要用触诊的方法进行检查。

Most, but not all studies, have shown untreated psychopathology to negatively impact LBP treatment outcomes.203 In the only study assessing the influence of psychopathology on l-z joint interventions, Lilius et al.204 found a strong correlation between a negative response to intraarticular and periarticular LA and steroid injections and inappropriate signs and symptoms.

大部分但并非所有研究认为未处理的精神疾病对LBP的治疗起反作用。在唯一一项评估精神症状多小关节疼痛的影响的研究中，Lilius等发现，关节内或关节四周LA及类固醇注射的反应和不良症状和体征见存在负相关。

Most, but not all studies, have shown untreated psychopathology to negatively impact LBP treatment outcomes.203 In the only study assessing the influence of psychopathology on l-z joint interventions, Lilius et al.204 found a strong correlation between a negative response to intraarticular and periarticular LA and steroid injections and inappropriate signs and symptoms.

大部分但并非所有研究认为未处理的精神疾病对LBP的治疗起反作用。在唯一一项评估精神症状多小关节疼痛的影响的研究中，Lilius等发现，关节内或关节周围LA及类固醇注射的反应和不良症状和体征见存在负相关。

Results(1) Group of electroacupuncture in Shu and dense wave can significantlyreduce the degree of ankle swelling(P＜0.05, P＜0.01), which shows thatelectroacupuncture has obvious anti-inflammatory and repercussive roles;(2) Theresults of HE staining showed that group of electroacupuncture in Shuand dense wave can significantly reduce inflammatory cell infiltration,inhibit synovial cell proliferation, and decrease proliferation of granulationtissue in rats joints;(3) group of electroacupuncture in dense-wave can increase the pain thresholdof experimental rats (P＜0.05, P＜0.01), reduce the content of peripheral painmediums, such as K~+, DA and 5-HT(P＜0.05, P＜0.01), which shows thatelectroacupuncture has significant analgesic effect;(4) In the local lesion of joints, electroacupuncture can significantly reducethe content of IL-1β, IL-8, TNF-a, increase IL-4 content, decrease theexpression of COX-2mRNA, and significantly promote the expression ofHSP-70 protein in synovial tissues of acute gouty arthritis rats (P＜0.05,P＜0.01),thus restrain the occurrence of synovial tissue inflammation.

结果：(1)电针疏密波组能显著减轻踝关节肿胀度(P＜0.05，P＜0.01)，表明电针有明显的抗炎消肿作用；(2)HE染色显示：电针疏密波组可使大鼠关节炎症细胞浸润明显减轻，滑膜细胞增生明显被抑制，肉芽组织增生明显减少；(3)电针密波组能提高实验性大鼠痛阈(P＜0.05，P＜0.01)，降低外周疼痛介质K~+、DA、5-HT的含量(P＜0.05，P＜0.01)，表明电针有明显的镇痛作用；(4)在病变关节局部，电针能显著降低急性痛风性关节炎大鼠滑膜组织IL-1β、IL-8、TNF-α含量(P＜0.05，P＜0.01)，升高IL-4的含量(P＜0.05，P＜0.01)，并降低关节滑膜内COX-2mRNA的表达(P＜0.05，P＜0.01)，可促使急性痛风性关节炎大鼠滑膜内HSP-70蛋白表达显著增加(P＜0.05，P＜0.01)，从而抑止滑膜组织炎症发生。

Objective:to investigate the treatment outcome of ao/asif clavicular hook plate in the treatment of acromioclavicular joint dislocation (tossy grade ⅲ)and unstable lateral clavicular fractures (neer type 2).methods: from february 2004 to march 2007,23 patients with unstable lateral clavicular fractures (neer type 2),2 patients with no-union lateral clavicular fractures and 5 patients with acromioclavicular joint dislocation (tossy grade ⅲ) were treated with acromioclavicular hook plate.

目的：探讨ao/asif锁骨钩钢板治疗锁骨骨折和肩锁关节脱位的疗效。方法：对2004年2月～2007年3月我科收治的30例得到完整随访资料的锁骨骨折和肩锁关节脱位的患者进行回顾性分析，其中，应用锁骨钩钢板治疗的新鲜锁骨外端不稳定骨折23例，陈旧性锁骨外端骨折骨不连患者2例，tossy grade ⅲ度肩锁关节脱位5例。

But if I want to…""Natasha, I am serious…" Natasha did not let her finish; she drew the countess's large hand to her, and kissed it on the upper side, and then on the palm, then turned it over again and began kissing it on the knuckle of the top joint of the finger, then on the space between the knuckles, then on a knuckle again, whispering:"January, February, March, April, May.""

如果我愿意……&&娜塔莎，我要一本正经地说……&娜塔莎不让伯爵夫人说完，就把她的一只大手拉到自己身边来，吻吻她的手背，然后吻吻掌心，又把手翻过来，开始吻她的手指的上关节，然后吻关节之间的地方，然后又吻上关节，同时轻言细语地说：&一月，二月，三月，四月，五月。&&

A shoe worn too big or too small will result in a stud being directly under the first MTP joint, affecting the joint as well as the sesamoids (the two small bones under the joint which protect it).

一个太大或者太小的球鞋的鞋钉会直接位于跖趾关节肌肉的下方，这样会对跖趾关节肌肉和籽骨(在跖趾关节肌肉下提供保护的2个小骨头)有不好的影响。

Plunder melds and run with this jewel!

掠夺melds和运行与此宝石！

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻，也许正是在通往天国的路上，我体验着这白色的晕旋。