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Artificial joint for wrist is gradually applied in clinic, and provides an alternation for patients with severe wound of wrist joint, anchylosis and severe traumatic arthritis.

人工腕关节逐渐被应用于临床,为因腕关节严重创伤、关节僵硬和严重创伤性关节炎的患者提供了一个可供选择的新方法。

In the four placebo-controlled studies evaluating radiofrequency denervation outcomes in patients with "confirmed"l-z joint pain, the only study that screened patients with MBB demonstrated positive outcomes,157versus only one of three that used diagnostic intraarticularin jections.158–160 Ultrasound-guided medial branchand intraarticular blocks have also been demonstrated to provide comparable accuracy to fluoroscopically guided injections, although they may be less likely to detect low-volume intravascular uptake and are less accurate in obese patients.161–164 Because MBB are technically easier to perform than intraarticular injections and involve anesthetization of the nerves to be lesioned, it seems more logical to use these blocks as a prognostic tool before radiofrequency denervation.

在四个设有安慰剂对照的对于&确诊&小关节疼痛的患者行射频神经消融后的结果的研究中,唯一一个用MBB筛选研究对象的实验表现出阳性结果,而其他3个用关节内注射筛选的实验中只有1个表现出阳性。超声介导下的内侧支关节囊内阻滞被证实较透视介导更精确,虽然其血管内吸收剂量较低且在肥胖的患者中精确性较差。由于MBB较之关节内注射技术上更简单,且能对受损神经进行麻醉,利用这种阻滞作为神经射频消融前的诊断方法较为合理。

The human cartilages are composed of chondrocyte and extracellular matrix,the form of chondrocytes are hypertrophy and the quantity are less;the ECM of cartilage are compised of type II collagen and proteoglycan. Articular cartilages are all hyaline with little fibers. Trauma and arthritis are the main cause of cartilage injury,the ommilayer injury ofcartilage can be recovered by marrow,but because of without stimulation mechanism,the new tissues are merely fibrocartilages,they can not be coincide with hyaline cartilage in menchanics;the purely damage of articular cartilage can not stimulate chondrocyte to regenerate because of without blood circulation,thus,the plerosis of articular catilage can not depend on the proliferation of local chondrocyte.Ever since,people tried their best to find a way to reconstruct articular cartilage.

造成人体关节软骨损伤的原因主要为创伤和关节炎,关节软骨全层损伤可由于骨髓中间充质干细胞的高速增殖修复,但这种修复由于缺乏相应的刺激机制,只能形成纤维软骨,而不能形成符合关节生理、力学要求的透明软骨;单纯软骨部分损伤软骨组织内无血管,软骨细胞迁移迟缓,无法使损伤区域软骨细胞再生,因此,关节炎及关节创伤后的软骨修复不能依赖于软骨细胞的增殖和迁移。

The human cartilages are composed of chondrocyte and extracellular matrix , the form of chondrocytes are hypertrophy and the quantity are less; the ECM of cartilage are compised of type Ⅱ collagen and proteoglycan. Articular cartilages are all hyaline with little fibers. Trauma and arthritis are the main cause of cartilage injury, the ommilayer injury ofcartilage can be recovered by marrow, but because of without stimulation mechanism, the new tissues are merely fibrocartilages, they can not be coincide with hyaline cartilage in menchanics; the purely damage of articular cartilage can not stimulate chondrocyte to regenerate because of without blood circulation, thus, the plerosis of articular catilage can not depend on the proliferation of local chondrocyte.

造成人体关节软骨损伤的原因主要为创伤和关节炎,关节软骨全层损伤可由于骨髓中间充质干细胞的高速增殖修复,但这种修复由于缺乏相应的刺激机制,只能形成纤维软骨,而不能形成符合关节生理、力学要求的透明软骨;单纯软骨部分损伤软骨组织内无血管,软骨细胞迁移迟缓,无法使损伤区域软骨细胞再生,因此,关节炎及关节创伤后的软骨修复不能依赖于软骨细胞的增殖和迁移。

The human cartilages are composed of chondrocyte and extracellular matrix , the form of chondrocytes are hypertrophy and the quantity are less; the ECM of cartilage are compised of type Ⅱ collagen and proteoglycan. Articular cartilages are all hyaline with little fibers. Trauma and arthritis are the main cause of cartilage injury, the ommilayer injury ofcartilage can be recovered by marrow, but because of without stimulation mechanism, the new tissues are merely fibrocartilages, they can not be coincide with hyaline cartilage in menchanics; the purely damage of articular cartilage can not stimulate chondrocyte to regenerate because of without blood circulation, thus, the plerosis of articular catilage can not depend on the proliferation of local chondrocyte. Ever since, people tried their best to find a way to reconstruct articular cartilage.

中文题名人骨髓基质干细胞成软骨诱导及多孔复合材料作为细胞载体的体外实验研究副题名外文题名 Cartilage induction of human mesenchymal stem cells and experiment on compound porous materials as cells' scaffold in vitro 论文作者刘晓岚导师周江南学科专业外科学研究领域\研究方向学位级别博士学位授予单位中南大学学位授予日期2003 论文页码总数68页关键词骨组织工程软骨细胞骨髓基质干细胞壳聚糖高分子外消旋聚乳酸馆藏号BSLW /2003 /R68 /10 造成人体关节软骨损伤的原因主要为创伤和关节炎,关节软骨全层损伤可由于骨髓中间充质干细胞的高速增殖修复,但这种修复由于缺乏相应的刺激机制,只能形成纤维软骨,而不能形成符合关节生理、力学要求的透明软骨;单纯软骨部分损伤软骨组织内无血管,软骨细胞迁移迟缓,无法使损伤区域软骨细胞再生,因此,关节炎及关节创伤后的软骨修复不能依赖于软骨细胞的增殖和迁移。

These findings indicate that this path of wrist motion confers a unique degree of radiocarpal stability and suggests that this direction, rather than the anatomical directions of wrist flexion-extension and radioulnar deiation, is the primary functional direction of the radiocarpal joint.

这些发现表明腕关节运动的轨迹以桡腕关节独一无二的稳定程度为对照的,这个方向是桡腕关节原始的功能方向,而不是腕关节屈曲及背伸及尺偏桡偏的解剖方向。

They were divided into two groups. Eight of them underwent lateral retinacular overlap suture and medial retinacular release operation to create patellofemoral articular cartilage degeneration.

山羊髌股关节和胫股关节软骨退变模型的建立选用山羊16只,其中8只采用外侧支持带紧缩和内侧支持带松解的方法制造髌股关节退变的模型,另外8只采用前交叉韧带切断和内侧半月板切除的方法制造胫股关节退变的模型。

Collar-bone hook nickelclad utilizes the lever principle and the intensity of nickelclad itself to oppose the traction force of sternomastoid muscle and avoid prolapse.As not damaging the acromioclavicular facet,it can avoid and reduce the traumatic arthritis caused by devices such as Kirschner wire ect.This method characterized by little wound,fixation firmly and moving the joint early is a effective method to cure distal collar bone fracture and acromioclavicular dislocation.

锁骨钩钢板利用杠杆原理和钢板自身的强度对抗胸锁乳突肌的牵引力,可以避免内固定物体的松动脱出,由于术中不损伤肩锁关节面,能够避免或减少克氏针固定等经关节手术所造成的继发性创伤骨关节炎,该方法创伤小、固定牢固,能早期活动肩关节,是治疗锁骨远端骨折和肩锁关节脱位行之有效的方法。

The patients can get painless free-running.Conclusion Collar-bone hook nickelclad utilizes the lever principle and the intensity of nickelclad itself to oppose the traction force of sternomastoid muscle and avoid prolapse.As not damaging the acromioclavicular facet,it can avoid and reduce the traumatic arthritis caused by devices such as Kirschner wire ect.This method characterized by little wound,fixation firmly and moving the joint early is a effective method to cure distal collar bone fracture and acromioclavicular dislocation.

锁骨钩钢板利用杠杆原理和钢板自身的强度对抗胸锁乳突肌的牵引力,可以避免内固定物体的松动脱出,由于术中不损伤肩锁关节面,能够避免或减少克氏针固定等经关节手术所造成的继发性创伤骨关节炎,该方法创伤小、固定牢固,能早期活动肩关节,是治疗锁骨远端骨折和肩锁关节脱位行之有效的方法。

The patients can get painless free-running.Conclusion Collar-bone hook nickelclad utilizes the lever principle and the intensity of nickelclad itself to oppose the traction force of sternomastoid muscle and avoid prolapse.As not damaging the acromioclavicular facet,it can avoid and reduce the traumatic arthritis caused by devices such as Kirschner wire ect.

锁骨钩钢板利用杠杆原理和钢板自身的强度对抗胸锁乳突肌的牵引力,可以避免内固定物体的松动脱出,由于术中不损伤肩锁关节面,能够避免或减少克氏针固定等经关节手术所造成的继发性创伤骨关节炎,该方法创伤小、固定牢固,能早期活动肩关节,是治疗锁骨远端骨折和肩锁关节脱位行之有效的方法。

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