关节炎

Results(1) Group of electroacupuncture in Shu and dense wave can significantlyreduce the degree of ankle swelling(P＜0.05, P＜0.01), which shows thatelectroacupuncture has obvious anti-inflammatory and repercussive roles;(2) Theresults of HE staining showed that group of electroacupuncture in Shuand dense wave can significantly reduce inflammatory cell infiltration,inhibit synovial cell proliferation, and decrease proliferation of granulationtissue in rats joints;(3) group of electroacupuncture in dense-wave can increase the pain thresholdof experimental rats (P＜0.05, P＜0.01), reduce the content of peripheral painmediums, such as K~+, DA and 5-HT(P＜0.05, P＜0.01), which shows thatelectroacupuncture has significant analgesic effect;(4) In the local lesion of joints, electroacupuncture can significantly reducethe content of IL-1β, IL-8, TNF-a, increase IL-4 content, decrease theexpression of COX-2mRNA, and significantly promote the expression ofHSP-70 protein in synovial tissues of acute gouty arthritis rats (P＜0.05,P＜0.01),thus restrain the occurrence of synovial tissue inflammation.

结果：(1)电针疏密波组能显著减轻踝关节肿胀度(P＜0.05，P＜0.01)，表明电针有明显的抗炎消肿作用；(2)HE染色显示：电针疏密波组可使大鼠关节炎症细胞浸润明显减轻，滑膜细胞增生明显被抑制，肉芽组织增生明显减少；(3)电针密波组能提高实验性大鼠痛阈(P＜0.05，P＜0.01)，降低外周疼痛介质K~+、DA、5-HT的含量(P＜0.05，P＜0.01)，表明电针有明显的镇痛作用；(4)在病变关节局部，电针能显著降低急性痛风性关节炎大鼠滑膜组织IL-1β、IL-8、TNF-α含量(P＜0.05，P＜0.01)，升高IL-4的含量(P＜0.05，P＜0.01)，并降低关节滑膜内COX-2mRNA的表达(P＜0.05，P＜0.01)，可促使急性痛风性关节炎大鼠滑膜内HSP-70蛋白表达显著增加(P＜0.05，P＜0.01)，从而抑止滑膜组织炎症发生。

Objectives:Through the detection of the expression level of interleukins-1β(IL-1β), matrix metalloproteinase 9(MMP-9) and nuclear factor kappa B in Synovium and the detection of the concentration of IL-6 and TNF-αin serum of collagen induced arthritis Wister rat, to investigate the relationship between IL-1β、MMP-9、NF-κB and arthritis index in the development of arthritis,and to understand the pathology of synoviocyte.This may provide an experimented proof for the diagnosis of clinical rheumatical arthritis. Methods: Thirty male Wistar rats were randomly divided into two groups,namely the model controlled group and the normal controlled group,three subgroups were randomly divided in model group and controlled group separately.

目的：通过对白细胞介素1β，基质金属蛋白酶-9，转录因子核因子κB在胶原性关节炎大鼠滑膜细胞表达水平的观察，同时监测同期血清细胞因子IL-6和TNF-α的浓度，旨在探讨白细胞介素1β，基质金属蛋白酶-9，转录因子核因子κB与RA发生发展及其与关节指数之间的相关性，了解炎性病变关节滑膜细胞的病理生理状态，进一步为类风湿关节炎的临床治疗提供实验依据。

Raynauds phenomenon, arthralgia/arthritis, fever, muscle involvement, swollen hands/sclerodactyly and abnormally elevated IgG and ESR levels were seen frequently in the disease course. Morbidity of pulmonary interstitial fibrosis was 40%. Renal involvement was not found in 15 cases of MCTD patients.

首发症状主要为雷诺现象(86.7％)，其次为关节痛／关节炎(13.3％)；临床表现中雷诺现象、关节痛／关节炎、发热、肌无力／肌炎、手指肿胀常见，实验室指标中IgG和血沉增高发生率高，肺间质病变发生率为40％，15例MCTD均无明显肾脏受累。

The univariate analysis between successful aging and MCI shows that education, marriage ,diet , exercise, somnus conduce to successful aging; drink ,smoke ,HBP , diabetes, COPD ,arthritis don"t conduce to successful aging .The multivariate analysis show that education, marriage ,diet ,exercise ,somnus conduce to successful aging; drink ,arthritis don"t conduce to successful aging.

成功老龄组与轻度认知损伤组单因素分析表明，文化程度、婚姻、饮食、饮酒、吸烟、锻炼、睡眠，高血压、糖尿病、慢性阻塞性肺病及关节炎病史等组间具有显著差异；多因素分析的结果提示较高的文化程度、婚姻、素食饮食、锻炼、正常的睡眠促进老龄化人群向成功老龄化转变，而饮酒、关节炎病史可使轻度认知功能损伤的可能性增加。

The multivariate analysis shows that marriage, habitation, diet, exercise, somnus conduce to successful aging and smoke, diabetes, arthritis do not conduce to successful aging .

成功老龄组与常态老龄组单因素分析显示，婚姻、饮食、吸烟、睡眠，高血压、糖尿病及关节炎病史等组间具有显著差异；多因素分析表明婚姻、居住方式、素食饮食、锻炼、正常的睡眠可促进老龄化人群向成功老龄化转变，而吸烟、糖尿病及关节炎病史则无促进作用。

Any form of arthritis that affects one or more vertebral joints, spondylarthritis represents a group of closely related disorders, including ankylosing spondylitis, psoriatic arthritis, and arthritis associated with inflammatory bowel disease.

凡是影响一个或更多脊椎关节的脊柱关节病，包括强直性脊柱炎，银屑病关节炎，和炎症肠病性关节炎都显示出一组紧密相关的症状。

Role of subchondral bone in osteoarthritis development: a comparative study of two strains of guinea pigs with and without spontaneously occurring osteoarthritis.

对有无自发骨性关节炎的两种品系豚鼠进行比较研究，观察软骨下骨在骨性关节炎发展中的作用

Osteoarthritis is a degeneration and loss of articular cartilage and joint marginal and subchondral bone regeneration,which is characterized by chronic arthritis of the disease.

随着人口老龄化的进展，骨关节炎的发病率逐年上升，发病年龄也有下降趋势，有资料报道45岁以上人群骨关节炎的发病率超过40%。

Results The values of bone density in weight-bearing, superolateral non weight-bearing and inferomedial non weight-bearing areas after femoral neck fracture in patients with osteoarthritis were lower than normal.

在骨密度测量方面，多数作者采用双能X线吸收测定法(dualenergyX rayabsorptiometry ，DEXA)，所获得的结果是骨性关节炎患者骨密度是增高的，并认为，骨密度增高可以降低骨折发生率；另外一些研究则显示骨性关节炎患者骨折发生率与致伤因素及暴力大小有关，与患者骨密度无关[2 ] 。

HUANG Jian,ZHUO Lianshi,WANG Yongyu(College of Traditional Chinese Medicine of Chongqing Medical University,401331,China)Abstract:ObjectiveTo observe the effects of massage on synovia SOD,MDA and NO contents in rabbits with Knee Osteoarthritis.

目的观察推拿加功能训练对膝骨关节炎家兔模型关节液中超氧化物歧化酶、丙二醛和一氧化氮的影响，探讨推拿加功能训练治疗膝骨关节炎的机制。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。