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Results: For normal living body. extensor hallucis longus was about (44±4.26)mm lateral to tibialis anterior muscle at the transverse striation of ankle,(2.00±2.22)mm lateral to the middle point of tarsometatarsal joint,(1.32±1.46)mm lateral to the middle point of metatarsophalangeal joint, and it inserted into the center of the base of distal phalanx with the range of (2.22±2.42) mm.

结果:正常长伸肌腱的位置在踝横纹处位于胫骨前肌外侧(9.44±4.26)mm,在跖附关节中点外侧(2.00±2.22)mm,跖趾关节中点外侧(1.32±1.46)mm,止点位于末节趾骨基底中点(2.22±2.42)mm范围内,长屈肌腱在跖趾关节中点外侧(0.44±2.42)mm。

Single joint was involved in two and multiple lesions in five of them,including the knees,elbow,wrist,phalangeal joint,metatarsophalangeal joint,metacarpophal...

根据病变严重程度分别采用关节抽吸冲洗类固醇注射、关节镜下病变清理术、痛风病灶清除术、刮除植骨术、Keller's手术及关节融合术治疗痛风病灶。

Flexor pollicis longus muscle tendon was about (0.44±2.42)mm lateral to the center of metatarsophalangeal joint. For cases of HV, extensor hallucis longus was about (9.32±3.46)mm lateral to tibialis anterior muscle at ankle transverse striation,(3.00±2.22)mm lateral to the center of tarsometatarsal joint.

在外翻的患者中,长伸肌腱在踝横纹处位于胫骨前肌外侧(9.32±3.46)mm,在跗跖关节中点外侧(3.00±2.22)mm,跖趾关节中点外侧(4.22±2.26)mm,止点位于末节趾骨基底中点(2.02±2.32)mm范围内,长屈肌腱在跖趾关节中点外侧(3.24±2.32)mm。

Results:(1) FSN can inhibit secondary joints swelling and multi-arthritis evidently, improve the whole condition of rats; at the same time, it can also lighten the synovial inflammation and hyperplasia of lesion joints distinctly, and prevent the joint cartilage and bone from destruction; the collective efficiency of FSN is better than TWP.(2) FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th / Ts and Thl / Th2 cells balance in peripheral blood, restrain exorbitant TNF- a ? IL-1 produced by PM O , thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF- a mRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflamination and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue,reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage.Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.

结果:(1)FSN有明显的抗炎作用,可显著抑制AA大鼠足跖肿胀与多关节炎,改善大鼠的全身情况,同时明显减轻病变关节滑膜炎症与增生,防止关节软骨及骨质的破坏,其综合作用优于TWP;(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常,纠正外周血中T细胞亚群Th/Ts及Th1/Th2平衡紊乱,抑制大鼠PHφ过高的TNF-α、IL-1分泌,而发挥抗炎和免疫调节作用;(3)在病变关节局部,FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达,降低滑膜组织中NF-kB表达,并增加凋亡蛋白酶Caspase-3表达,从而抑制滑膜的炎症与增殖;(4)FSN还可下调滑膜组织中VEGF表达,减少血管新生,由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀;(5)FSN的上述作用皆呈现一定的量效依赖关系,高剂量组作用优于低剂量组。

FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th/Ts and Th1/Th2 cells balance in peripheral blood, restrain exorbitant TNF-α、IL-1 produced by PMφ, thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF-αmRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflammation and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue, reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage. Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.

结果:(1)FSN有明显的抗炎作用,可显著抑制AA大鼠足跖肿胀与多关节炎,改善大鼠的全身情况,同时明显减轻病变关节滑膜炎症与增生,防止关节软骨及骨质的破坏,其综合作用优于TWP;(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常,纠正外周血中T细胞亚群Th/Ts及Th1/Th2平衡紊乱,抑制大鼠PMφ过高的TNF-α、IL-1分泌,而发挥抗炎和免疫调节作用;(3)在病变关节局部,FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达,降低滑膜组织中NF-kB表达,并增加凋亡蛋白酶Caspase-3表达,从而抑制滑膜的炎症与增殖;(4)FSN还可下调滑膜组织中VEGF表达,减少血管新生,由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀;(5)FSN的上述作用皆呈现一定的量效依赖关系,高剂量组作用优于低剂量组。

Objective: To clarify the technical parameters in posterior atlanto-occipital transarticular screw fixation and discuss the clinical significance of occipitocervical junction fixation with transarticular screws.

目的:明确后路寰枕关节关节螺钉固定的技术参数;探讨枕颈部经关节螺钉内固定技术的临床意义。

Direction and length of trajectory are the key of posterior atlano-occipital transarticular fixation, if combined with C1-C2 transarticular fixation, it will be an ideal fixation method for occipitocervical fusion.

寰枕关节后路经关节螺钉植入存在一定的方向性和钉道长度,结合后路C1-C2经关节螺钉内固定后可视为能满足当前临床需要的一种相对理想的枕颈融合内固定术式。

ABSTRACT Osteoarthritis is a common degenerative arthritis disease with articular cartilage damage, and the main pathologic character is degeneration of cartilage, osteophyma production, cellular proliferation, synovitis and narrow joint space.

关节炎(Osteoarthritis,OA)又称退行性关节炎,是以关节软骨损坏为特征的一种慢性进行性关节疾患,其主要病理特征是关节软骨的变性破坏和丢失,。。。

Palpate for tenderness at the sternoclavicular joint, the acromioclavicular joint, the subacromial area...

对于胸骨锁骨处的关节,肩峰处的关节以及肩背处的关节这样敏感的部位要用触诊的方法进行检查。

Results Extensive and diffuse synovial hyperplasia can be seen in patients with RA;synovial pannus formation can be seen in 25 cases.

结果RA组病人均可见广泛、弥漫的滑膜增生,其中25例病人可见滑膜血管翳形成,而OA组仅7例病人可见轻度滑膜增厚,未见滑膜血管翳形成者(X2=55.78P.005);RA组关节软骨及软骨下骨改变较严重且弥漫,而OA组软骨退变则较局限,且以关节摩擦大的部位受损为著,其软骨下骨改变较为局限,常常见于IV软骨退变;关节腔积液、半月板及韧带改变,在OA组与RA组之间无差异。

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这是谁的?