兰德斯

Antigene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis Roberto Tonelli,Stefania Purgato,Consuelo Camerin,Raffaele Fronza,Fabrizio Bologna,Simone Alboresi,Monica Franzoni,Roberto Corradini,Stefano Sforza,Andrea Faccini,Jason M. Shohet,Rosangela Marchelli,and Andrea Pession Department of Pediatrics, University of Bologna,Sant'Orsola-Malpighi Hospital, Bologna, Italy; Department of Organic and Industrial Chemistry, University of Parma, Parma,Italy; and 3Center for Cell and Gene Therapy, Texas Children's Cancer Center, Baylor College of Medicine, Houston, Texas Abstract We developed an antigene peptide nucleic acid for selective inhibition of MYCN transcription in neuroblastoma cells, targeted against a unique sequence in the antisense DNA strand of exon 2 of MYCN and linked at its NH2 terminus to a nuclear localization signal peptide.

抗原肽核酸抑制MYCN具体表达的神经母细胞瘤细胞，导致细胞生长的抑制和凋亡罗伯托利，斯特凡Purgato ，苏埃洛卡默琳，拉菲尔Fronza ，梅奥尼博洛尼亚，西蒙娜Alboresi ，莫妮卡弗兰索尼，罗伯托Corradini ，斯特凡诺斯福尔扎，安德烈Faccini ，杰森先生Shohet ， Rosangela Marchelli ，和安德烈Pession儿科，博洛尼亚大学，圣' Orsola -马尔皮基医院，博洛尼亚，意大利；有机部和工业大学化学帕尔马，帕尔马，意大利和3Center的细胞和基因治疗，德州儿童癌症中心， Baylor医学院，得克萨斯州休斯敦摘要我们开发了一种抗原肽核酸的选择性抑制神经母细胞瘤MYCN转录细胞，针对一个独特的序列反义DNA链的第2外显子，并与在MYCN 其氨基端为核定位信号肽。

The journey takes Edmund, Lucy, and their cousin Eustace to the Eastern Islands, beyond the Silver Sea, toward Aslan's country as the End of the World.

这航行带着埃德蒙德，露西，和他们的表兄弟尤斯塔斯到东边群岛，到银海的另一边，直至世界的尽头，阿斯兰的家乡。

SB Babbage, Man in Nature and Grace; E Brunner, Man in Revolt; G Carey, I Believe in Man; S Cave, The Christian Estimate of Man; D Cairns, The Image of God in Man; W Eichrodt, Man in the OT ; WG Kummel, Man in the NT ; J Laidlaw, The Bible Doctrine of Man; JG Machen, The Christian View of Man; HD McDonald, The Christian View of Man; J Moltmann, Man; J Orr, God's Image in Man; HW Robinson, The Christian Doctrine of Man; RF Shedd, Man in Community; CR Smith, The Bible Doctrine of Man; WD Stacey, The Pauline View of Man; TF Torrance, Calvin's Doctrine of Man; CA vanPeursen, Body, Soul, Spirit; JS Wright, What Is Man?

锑巴贝奇，人在自然和恩典；电子邮件布，人在起义； G凯里，我相信人；山洞，基督教估计人； D凯恩斯，图像在上帝的人； W Eichrodt ，人在加时赛；工作组Kummel ，人在新台币； J莱德劳，圣经学说的人； JG麦，基督教观的人；高清麦当劳，基督教观的人； J莫尔特曼，男； J奥尔，上帝的形象在人；老罗宾逊，基督教学说的人；射频谢德，人在共同体；责任史密斯，圣经学说的人；的WD斯泰西，波利娜观的人；因子托兰斯，加尔文的学说的人；加利福尼亚州vanPeursen ，身体，灵魂，精神；江苏赖特，什麼是人？

Other authors include Daniel Apai of the Space Telescope Science Institute, Baltimore, Md.; Kevin Luhman of Pennsylvania State University, University Park; Thomas Henning and Jeroen Bouwman of the Max Planck Institute for Astronomy, Germany; Michael Meyer of the University of Arizona, Tucson; Fred Lahuis of the SRON Netherlands Institute for Space Research, the Netherlands; and Antonella Natta of the Arcetri Astrophysical Observatory, Italy.

其他论文作者：马里兰州巴尔的摩市太空望远镜科学研究所的丹尼尔·Apai；宾西法尼亚州立大学的凯文·Luhman；德国马克士普朗克天体物理研究所托马斯·亨宁和Jeroen·Bouwman；图森市亚利桑那大学的迈克尔·梅耶尔；荷兰尼德兰空间研究协会的弗雷德·拉豪斯；意大利佛罗伦斯市雅赛墔天体物理观测站的Antonella·纳塔等。

Other authors include Daniel Apai of the Space Telescope ScienceInstitute, Baltimore, Md.; Kevin Luhman of Pennsylvania StateUniversity, University Park; Thomas Henning and Jeroen Bouwman of theMax Planck Institute for Astronomy, Germany; Michael Meyer of theUniversity of Arizona, Tucson; Fred Lahuis of the SRON NetherlandsInstitute for Space Research, the Netherlands; and Antonella Natta ofthe Arcetri Astrophysical Observatory, Italy.

其他论文作者：马里兰州巴尔的摩市太空望远镜科学研究所的丹尼尔·Apai；宾西法尼亚州立大学的凯文·Luhman；德国马克士普朗克天体物理研究所托马斯·亨宁和Jeroen·Bouwman；图森市亚利桑那大学的迈克尔·梅耶尔；荷兰尼德兰空间研究协会的弗雷德·拉豪斯；意大利佛罗伦斯市雅赛墔天体物理观测站的Antonella·纳塔等。

Gargle twice a day with warm salt water (use Listerine if you don't trust salt).

每天用温盐水（或李斯德林漱口水，武藤兰照片触摸武藤兰武藤兰视频武藤兰怎么死的如果你不太相信盐水有效的话）漱口两次。

Was the first president to understand television, and Howard Dean saw the value of the Web for raising money," said Ranjit Mathoda, a lawyer and money manager who blogs at Mathoda.com ."

&托玛斯·杰弗逊利用报纸赢得了总统职位，富兰克林·德拉诺·罗斯福利用广播改变了他执政的方式，约翰·F·肯尼迪是第一个认识到电视作用的总统，霍华德·迪恩看见了用网络进行筹款的好处，&兰吉特·马瑟达，这个律师兼资金经理，他在自己的博客上说。

Years 5 31, the British commander-in-chief Lord Roberts entered Johannesburg, June 5 occupied Transvaal in Pretoria, the capital, in September announced that the British annexation of the Transvaal.

1900年5月31日，英军总司令罗伯茨勋爵进入约翰内斯堡，6月5日占领德兰士瓦首府比勒陀利亚，9月英国宣布吞并德兰士瓦。

Other notables: Trevor Ariza, Lakers; Anthony Parker, Raptors; Zaza Pachulia, Hawks; Jeff Foster, Pacers; Brandon Bass, Mavs; Marquis Daniels, Pacers; Wally Szczerbiak, Cavs; Joe Smith, Thunder; Stephon Marbury, Knicks; Grant Hill, Suns; Stromile Swift, Nets; Robert Swift, Thunder; Rasho Nesterovic, Pacers; Keith Bogans, Magic; Jason Williams, Clippers; Bobby Jackson, Kings; Damon Jones, Bucks; Desmond Mason, Thunder; Chris Mihm, Lakers; Jason Collins, Timberwolves; Jarron Collins, Jazz.

其他值得关注的球员：湖人的特雷弗-阿里扎、猛龙的安东尼-帕克、鹰队的帕楚利亚、步行者的杰夫-弗斯特、小牛的布兰顿-巴斯、步行者的马奎斯-丹尼尔斯、骑士的沃利-泽比亚克、雷霆的乔-史密斯、尼克斯的史蒂芬-马布里、太阳的格兰特-希尔、网队的斯威夫特、雷霆的罗伯特-斯威夫特、步行者的内斯特洛维奇、魔术的基夫-伯根斯、快艇的杰森-威廉姆斯、国王的鲍比-杰克逊、雄鹿的戴蒙-琼斯、雷霆的迪斯蒙德-梅森、湖人的克里斯-米姆、森林狼的贾森-柯林斯、爵士的加隆-柯林斯。

I also published horror or dark fantasy by Carol Emshwiller, Jack Dann, Jack Cady, Jonathan Carroll, Greg Bear, Pat Cadigan, Stephen King, Lucius Shepard, Edward Bryant, Scott Baker, Simon Ings, Harlan Ellison (his "Mefisto in Onyx" won the Stoker).

我还发表过卡罗尔·艾姆什维勒、杰克·唐恩、杰克·凯迪、乔纳森·卡罗尔、格雷格·贝尔、帕特·凯迪根、斯蒂芬·金、卢修斯·谢帕德、爱德华·布莱恩特、斯科特·贝克、西蒙·英格斯、哈兰·埃里森（《 Mefisto in Onyx 》获得布莱姆·斯托克奖）的恐怖和黑暗奇幻小说。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐