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Methods: On the basis of cloning the M-TNF c D NA encoding region,the authors constructed mTNFm,which could potentially expre ss on the c ell surface with a uncleavable type of TNF resulting in deletion of the sequence encoding enzymatic cleavage site of TNF-α-converting enzyme.

近年来研究表明,T NF的两种形式在受体结合、生物学效应等方面各具特征[3,4]。M-TNF通过直接接触在组织局部中发挥效应的特性,有望克服S-TNF在生物治疗应用中引起的远端及全身性毒副作用。

A kind of M-TNF recombin ant with a stable,uncleavable mutant typewas constructed for its gene therap y. Methods: On the basis of cloning the M-TNF c D NA encoding region,the authors constructed mTNFm,which could potentially expre ss on the c ell surface with a uncleavable type of TNF resulting in deletion of the sequence encoding enzymatic cleavage site of TNF-α-converting enzyme.

近年来研究表明,T NF的两种形式在受体结合、生物学效应等方面各具特征[3,4]。M-TNF通过直接接触在组织局部中发挥效应的特性,有望克服S-TNF在生物治疗应用中引起的远端及全身性毒副作用。

It has been accepted that EH is a general disease resulted from multiple factors, with cell abnormal proliferation as a prominent pathological character Arginine vasopressin, a vasoconstrictive peptide secreted from hypothalamus, is believed to be involved in EH and its pathological leisons.

现已证实,EH是一种在众多致病因素共同作用下,以细胞异常增殖为主要病理学特征的全身性疾病。

The prevalence rate is 3%-4% in Hong Kong. Generalised osteopenia are found in AIS patients.

在香港有3%~4%的发病率,AIS的病人同时发现患有全身性的骨密度偏低现象。

Sarcoidosis is an idiopathic systemic disease which is characterized by the presence of non-caseating granulomas without infection or malignancy.

类肉瘤病是一种全身性的疾病其特点表现为非乾酪性肉芽肿。

The portal vein ligated rat is the experimental model most widely used to study this syndrome and it has been considered that a systemic inflammatory response is produced.

最常用的研究本症状的模型是结扎小鼠门静脉主干建立动物模型,并且它被认为有全身性炎症反应产生。

Methods Forty cases with acute exacerbation of COPD were randomly divided into two groups,treated with nebulized budesonide suspension or systemic glucocorticoids.

40例COPD急性加重期患者随机分成治疗组和对照组各20例,分别给予布地奈德混悬液及全身性应用糖皮质激素。

Of 14 patients with moderate to severe SLE refractory to steroids plus one or more immunosuppressive drugs, 12 were female, four were African-American, nine had progressive renal lupus, and one had an ulcerating lupus rash covering 60% of her body. Mean age was 35 years.

在本研究中共有14位中到重度的全身性红斑狼疮患者,即使以类固醇加上一种或一种以上的免疫抑制剂都难以治愈,其中12位为女性,4位为非裔美国人,9位为进行性狼疮性肾炎,1位全身60%以上被溃疡性狼疮红疹所覆盖,平均年龄约为35岁。

Pharmacology function 】the anti-virus table of this article with anti-virus activity and ammonia Xia west wood likeness, because of it at absorb of unit animal ratio ammonia Xia west Lin2 Hao3, blood medicine density Gao, is an ammonia Xia west wood of 300% above, past to whole body sexy dye of the curative effect be better.

本品的抗菌谱与抗菌活性与氨苄西林相似,由于其在单位动物的吸收比氨苄西林好,血药浓度高,是氨苄西林的3倍以上,故对全身性感染的疗效较好。

Aerobes may be eliminated gradually after operation, and its likely to reach the normal state; the postoperative recovery of mucosa and mucociliary transport system seems to be a vital contributor for it. Two months maybe a transition during the repairing stage if systemaitcally postoperative cares engaged;5. Insights fro

在加强综合性术后处理基础上,两个月左右可能是一个转折点: 5、从微生态学角度出发,在慢性鼻窦炎中,全身性或局部抗微生物药物应用的必要性值得重新评价。

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It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发,分析对称连杆曲线上鲍尔点的产生条件,提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品,年生产总值3000万美元,产品价廉物美、选料上乘、质量保证,深受国内外客户的青睐

The eˉtiology of hemospermia is complicate,but almost of hemospermia are benign.

血精的原因很,以良性病变为主。