免疫遗传的

The key to feature extraction is to select the optimal feature combination from all the features. In this study, the optimal color feature combination,{/G,(R+4G+B)/6, H variance, S variance}, is selected using genetic neural network at first. Then the main texture features including the mean, variance, energy and entropy of the cooccurrence matrix, the secondary texture features including the maximum frequency number, absolute uniform, inertia and importance of the co-occurrence matrix are extracted.

在此基础上，提出适合多阈值和小目标图像分割的免疫遗传图像分割方法，该方法借鉴了生物免疫系统自调节、抗原识别和记忆功能，并结合了遗传算法对图像进行自适应区域的阈值分割，改善了遗传算法优化复杂问题时存在收敛速度慢和易陷于局部最优的不足，克服了传统阈值分割方法对目标大小的限制，是一种新型的有效的图像分割方法。

Image matching algorithm which based on directed Hausdorff distance and immune genetic algorithm consists of defining code and adaptive degree function, confirming intercross variation operator and immune operation.

部分Hausdorff 距离和免疫遗传算法相结合的图像匹配算法包括：定义编码与适应度函数、确定交叉变异算子及免疫操作。

In the comparison experiments with genetic algorithm,immune genetic algorithm,basic particle swarm optimization algorithm and so on,IPSO performs well with best solution and fastest convergence speed.

在与遗传算法、免疫遗传算法、基本微粒群等算法的仿真比较试验中，该算法不仅搜索到了最好的近优解，而且收敛速度最快。

In order to increase the speed of convergence, an immune genetic algorithm based on vaccine autonomous obtaining and updating is proposed.

为了提高遗传算法的收敛速度，提出了一种基於疫苗自动获取与更新的免疫遗传算法。

In the case of keeping individual diversity and improving the level of adaptability of the individual diversity in the population,the immune genetic algorithm based on selection probability of similarity and vector distance is proposed.

为了防止基于相似性矢量距为选择概率的免疫遗传算法在优化过程中出现退化现象，通过在算法中引入免疫疫苗的方式，对该算法进一步加以改进。

To explore the immunogenetic mechanism of association between human leukocyte antigen and Hp and associated gastritis to search for the possible existence of susceptibility or resistance gene to the disease.

本研究为探讨人类白细胞抗原-DQA1（HLA-DQA1）基因位点上是否存在与Hp感染及其相关胃炎的易感基因或抵抗基因，研究其与免疫遗传的相关性。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病，不管是急性淋巴性白血病或是急性骨髓性白血病，在染色体11q23部位有染色体易位的情况；这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是，单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%；并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且，这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后，而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖，遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以，白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

As a result, the searching converges earlier and we can't get the solution of the optimization. Therefore, a pseudo-parallel immune genetic algorithm is proposed, which inoculates populations generated by GA to improve the searching speed and reject premature phenomenon according to the characteristic of a certain problem and the parallel theory.

为此，提出了一种伪并行免疫遗传算法，在微机上利用求解问题特征以及并行思想对遗传算法的种群进行免疫接种，并进行伪并行运算，以提高搜索速度，克服早熟现象。

Product color intelligent design and optimization techniques based on genetic andimmunity theory This paper introduces genetic and immunity theory into PCID study, establishes a genecoding principle based on product subassembly, constructs a fitness function of colorschemes according to SCCA model, applies genetic and immunity algorithm to simulate theradiation and convergence process of MT, at last it builds a product color design model.Experiments prove that this method can design and optimize color schemes on its own.

5基于遗传与免疫理论的产品色彩方案生成与优化技术把基因遗传和生物免疫理论引入产品色彩智能设计中，提出以产品组件为基本进化单元的基因编码方法，根据形色耦合美度模型构造了色彩方案适应度函数，综合应用遗传算法与免疫算法模拟色彩设计复合思维的发散和聚敛过程并构建了色彩创新模型，算例表明该模型能解决产品色彩方案的自动生成与优化问题。

Therefore, this algorithm is applied to inverse analysis of mechanical parameters in Pump and Brake Program .It is shown that this algorithm can be used for back analysis of mechanical parameters in engineering.

基于该算法进行了泵闸工程力学参数的反演分析，结果表明免疫遗传算法结合了遗传算法和免疫算法的优点，可以在工程中广泛应用。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。