免疫素

Locksley beliees that AMCase, comparable to the chitinolytic enzyme found in marine and soil bacteria—and likely consered in human eolution—attenuates the chitin-induced innate immune response by degrading the chitin.

洛克斯利相信AMCase比得上在海洋和土壤细菌中发现的甲壳素消化酶－并且可能在人类进化中保存下来了－通过降解甲壳素减弱了甲壳素诱导的先天性免疫反应。

Methods 43 patients with IBS and 20 healthy subjects were comparatively investigated. Anorectal pressure was measured with anorectal catheta of solid state manometric transducers.Gastrointestinal hormones in plasma including gastrin,glucagen,were measured with radioimmunossay.

采用五通道环状固态压力传感器测压导管测定43例IBS患者直肠肛管的压力，以及采用放射免疫分析法检测血浆胃泌素、胃动素、胰高糖素的水平，并与20例正常人作对照。

Methods ①In situ hybridization was applied to observe the changes ofhypothalamic CRHmRNA positive cells after PX and melatonin supplementation;②Immunohistochemistry was used to observe the changes of CRH positive cellsin hypothalamus and CRH staining in median eminence of neurohypophysis after PXand melatonin supplementation;③ELISA was applied to detect the changes of CRHconcentration in serum after PX and melatonin supplementation.

①运用CRHmRNA 原位杂交的方法来观察松果体摘除及补充外源性褪黑素后下丘脑室旁核CRHmRNA 阳性细胞的变化；②应用免疫组织化学染色的方法观察松果体摘除及补充外源性褪黑素后下丘脑室旁核CRH 阳性细胞和神经垂体正中隆起CRH 阳性染色的变化；③运用ELISA 法检测松果体摘除及补充褪黑素后血清CRH 浓度的变化。

Radioimmunoassaywas utilized to measure levels of angiotensin Ⅰ, angiotensin Ⅱ and plasma rennin activity, respectively.

用放射免疫法测定血管紧张素Ⅰ、血管紧张素Ⅱ和血浆肾素活性。

In our islet transplantation program nonhuman primates with STZ-induced diabetes received transplants under chronic immunosuppression including calcineurin inhibitors, drugs in the rapamycin class affecting growth factor-induced cell proliferation, and the sphingosine 1-phosphate receptor antagonist FTY720. Four animals developed renal failure and had to be sacrificed, most likely caused by cyclosporine.

在我们应用STZ诱导的糖尿病的灵长类动物性胰岛细胞移植的病例长期应用的免疫抑制剂包括：钙神经素拮抗剂，雷帕霉素和神经鞘氨醇1－磷酸盐FTY720.4个动物死于肾功能衰竭，这很可能是由于环孢素引起的。

Thunberg Fritillary Bulb is one of the most popular Traditional Chinese herbs. Some trials in vivo and animals indicated that Peimine and Peiminine, extracted from Thunbery Fritillary Bulb, have the function of reversing MDR of two different kinds of mechanisms. They can improve the cytotoxic of ADR to cancer cells by 5～10 folds under concentration of 10% cancer cell growth inhibitory rate. Peimine and Peiminine not only feather typical character of modifier of MDR, but also differ from other moldifiers such as Calcium channel blocker, Cyclosporines in chemical structure, they belong to cevine groups alkaloid, a subgroup of C-Nor-D-homosteroid alkaloid.

浙贝母是临床常用中药，体外及动物试验证明，浙贝母中的有效活性成分贝母甲素和贝母乙素具有逆转肿瘤细胞MDR的作用，而且能逆转两种不同机制的多药耐药肿瘤细胞的耐药性，在无明显细胞毒剂量下，可使阿霉素对耐药肿瘤细胞的杀伤活性提高5-10倍，不但具备明确的多药耐药逆转剂的特征，而且在化学结构上属异甾类生物碱中的瑟文类生物碱，完全不同于钙离子拮抗剂、免疫抑制剂和其它现有的耐药逆转剂，具有作用靶点宽、化学结构独特的特点。

Methods Serum contents of hyaluronic,type IV collagen,cholalic acid,tumor necrosis factor,transforming growth Factor-α,interleukin-1(IL-1),interleukin-6(IL-6)and interleukin-8(IL-8)were detected by radioimmunoassay and were analyzed.

方法应用放射免疫法对患者血清透明质酸、IV型胶原、胆酸、肿瘤坏死因子、转化生长因子-α、白细胞介素-1(IL-1)、白细胞介素-6(IL-6)和白细胞介素-8(IL-8)进行测定和分析。

Venous blood was drawn from 35 old hypertension patients when blood pressure was nomial and abnormal, respectively. Epinephrine. norepinephine, endothelins, angiotensin Ⅱ and calcitonin-gene-related peptide were determined by radio-immunity. The above five cytokines were also determined in 33 old healthy people. The cytokines levels were compared between the normal and abnormal blond pressure in hypertension patients and also between the old hypertension patients and healthy persons. The correlation between blood pressure and cytokines were analyzed.

35例老年EH患者，血压正常时和血压波动时各抽取静脉血一次，放射免疫法检测肾上腺素、去甲肾上腺素、内皮素、血管紧张素Ⅱ和降钙素基因相关肽水平，同时检测33例健康老年人群各因子水平，比较EH患者血压波动前后各因子水平的差异和血压正常范围时两组人群各因子水平差异，分析不同状态下血压和各因子水平之间的相关性。

Cell membrane nonpermeable inhibitor of calmodulin -W〓-agarose- and the anti-serum of calmodulin can decrease the cytosolic calcium level, the results show that the endogeneous extracellular calmodulin may play an important role in maintaining and accelerating the cytosolic calcium level in pollen grain cell.

不能透过细胞膜的钙调素抗血清和大分子钙调素拮抗剂W〓-agarose处理后细胞内钙离子水平降低，免疫前血清对花粉细胞内钙离子浓度没有明显影响；进一步支持了上述结果，并且表明内源细胞外钙调素在维持和提高细胞内钙离子浓度方面发挥作用。

Most 5-HT cells appeared in the base part of gland in the rat, while in the human they were mainly located in the intercellular substance and a few scatted in the glandular epithelium.

方法采用免疫细胞化学方法，检测人和大鼠胃窦部粘膜内生长抑素细胞、胃泌素细胞、5-羟色胺细胞（5-HT细胞）、嗜铬粒素A细胞的分布。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。