免疫素

Methods ①Human peptides of CYP450 enzymes and their proteinic sequence were analyzed by means of bioinformatics, and certain sequences were chosen and synthesized according to four indexes (Hydrophilicity Plot, Flexible Regions, Antigenic Index and Surface Probability Plot) after homology analysis by software Blast. The synthesized peptides were conjugated to keyhole limpet hemocyanin to increase antigenicity.

①利用生物信息学方法分析CYP1A2、CYP3A4及CYP4A11蛋白的序列，利用DNAstar软件中蛋白质的亲水性结构、柔韧区、抗原指数及表面概率结构指标选择多肽序列，应用Blast软件对所选序列进行同源性分析并合成多肽，与载体蛋白钥孔戚血蓝素偶联，免疫大耳白兔制备抗CYP1A2、3A4及4A11抗体。

Keywords: lumenal signal molecule; casomorphin; endocrine; immunity; gastrin

中文关键词：腔内信号分子；酪啡肽；内分泌；免疫；胃泌素

Interleuk in 2 (IL-2) is an important cytokine released from activated T lymphocytes, which activated lymphokine actived killer cells and natural killer cells , and promoted cytokine production of helper T Cells and natural killer cells , and stimulated T cell growth in vitro and so on . It plays a important role in body immune regulator.

白细胞介素2主要是由激活的T淋巴细胞产生的一类重要的细胞因子，具有激活淋巴因子活化的杀伤细胞和自然杀伤细胞，刺激T辅助细胞和自然杀伤细胞产生细胞因子和促进细胞因子的繁殖以及刺激T细胞在体外生长等功能，因此它是在免疫调节中有重要作用。

Basic fibroblast growth factor ; lymphokine activated killer cells ; cell division ; interleukin 2; bladder neoplasms ; immunologic cytotoxicity

碱性成纤维细胞生长因子；淋巴因子激活的杀伤细胞；细胞分裂；白细胞介素-2；膀胱癌；免疫细胞毒性

Nasopharyngeal neoplasms/radiotherapy ; immunity ; cellular/analysis ; interleukin 2/therapy ; killer cells ; lymphokine activated/therapy

鼻咽肿瘤/放射疗法；免疫；细胞/分析；白细胞介素2/治疗；杀伤细胞；淋巴因子激活/治疗

Tretinoin ; vitamin A ; lymphokine activated killer cells ; cell division ; interleukin 2; immunologic cytotoxicity ; cultured tumor cells ; bladder neoplasms

维A酸；维生素A ；淋巴因子激活的杀伤细胞；细胞分裂；白细胞介素-2；免疫细胞毒性；培养的肿瘤细胞；膀胱癌

Methods Solid-tumor-bearing mice were produced with Lewis lung cell and randomly divided into radiation group (n=18) and control group (n=17).The mice in the radiation group were irradiated by 30 Gy X-ray. The expressions of E-cadherin and MMP-9 were detected by immunohistochemical. Results After two weeks of therapy.

建立Lewis肺癌模型，将荷Lewis肺癌的C57BL/6雄性小鼠35只随机分为照射组(n=18)和对照组(n=17)，照射组接受30 Gy的X线肿瘤局部照射，对照组不接受照射，2周后采用免疫组化法检测瘤组织中E-钙黏素蛋白和基质金属蛋白酶－9(MMP-9)蛋白的表达。

MethodsSolidtumorbearing mice were produced with Lewis lung cell and randomly divided into radiation group (n=18) and control group (n=17). The mice in the radiation group were irradiated by 30 Gy Xray. The expressions of Ecadherin and MMP9 were detected by immunohistochemical.ResultsAfter two weeks of therapy.

建立Lewis肺癌模型，将荷Lewis肺癌的C57BL/6 雄性小鼠35只随机分为照射组（n=18）和对照组（n=17），照射组接受30 Gy的X线肿瘤局部照射，对照组不接受照射，2周后采用免疫组化法检测瘤组织中E钙黏素蛋白和基质金属蛋白酶9(MMP9)蛋白的表达。

At the endpoint, the thymus, spleen and uterus were weighed separately; the femoral dry weight, bone-calcium, phosphor, magnesium and hydroxyproline contents of femoral were measured; the histomorphological features of bone were observed and the biochemical indexes in serum (Ca, P, ALP, TRAP, E2, BGP) were determined after the mice were given SAR at the dose of 10, 30, 90 mgkg^(-1) respectively, and were compared with the model group, the normal control and the positive control. RESULTS: The osteoporosis of high turnover type was formed with feeding retinoic acid to experimental mice. Compared with the model group, the lessening of femoral dry weight, the short femoral transverse diameter, the decrease of bone mineral and bone-hydroxyproline of SAR groups were improved.

维A酸105mgkg^(-1致小鼠骨质疏松模型，SAR10、30、90mgkg^(-1灌胃给药，实验过程监测体重，2周后以比色法测定血清钙、磷含量和碱性磷酸酶、抗酒石酸酸性磷酸酶活性，竞争放射免疫法测定血清中骨钙素、雌二醇(s-E2)含量，处死动物后取脾、胸腺、子宫称重，取股骨进行骨组织形态学观察，测定并比较骨计量学和骨钙、骨磷、骨镁及骨弃脯氨酸含量。

Methods The levels of thyroxin FT 3,FT 4 and thyrotrophin in the serum of patients with alopecia areata and normal controls were detected by radioimmune assay.

采用放射免疫分析法检测 6 0例斑秃病人和正常人血清中甲状腺FT3 、FT4及促甲状腺素的水平。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。