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This product can increase immunity of livestock and poultry, enhance the activity of phagocyte, which otherwise can not be performed by normal microorganism flora parasitized in animal intestinal tract.

禽畜机体内正常的微生物菌群对机体的免疫系统具有重要的诱发作用,本品可提升动物肠内免疫系统细胞,使一般非特异免疫功能得到协调和提高,加大吞嗜细胞的活性,这些并非原宿于禽畜肠道内微生物菌系所能达到的。

Research topics in the Department are wide-ranging and include the cellular and molecular analysis of infection and immunity, the virulence of enteropathic bacteria, the microbial diversity of tissues, environmental microbiology, innate immunity, human respiratory virology, pulmonary immunology, the virulence of pneumococci, tumour immunology and immunodeficiency.

部门研究主题广泛包括;传染和免疫细胞和分子分析,肠病细菌的毒性,组织微生物的多样性,环境微生物学,先天免疫,人类呼吸器官的滤过性微生物学,肺部免疫学,肺炎双球菌的毒性,肿瘤免疫学和免疫缺陷。

The thymuses, spleens, sera and anticoagulant blood were collected after the rats were killed, to carry out these works:(1) Zinc concentrations were analyzed by atomic absorption spectrophotometry;(2) Body weight and the weight of thymuses and spleens were measured, the organ index were calculated;(3) Changes in pathology of thymus and spleen were observed;(4) Using TUNEL (terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling) method, the apoptosis of thmocytes and spleen lymphocytes was checked;(5) The expression of bcl-2、bax mRNA in thymus and spleen were detected by RT-PCR (reverse transcription polymerase chain reaction);(6) The expression of p56〓, a signal transduction protein in thymus and spleen were detected by immunohistochemistry;(7) Two-color cytofluorometric analysis was used to assess the expression of CD4, CD8, CD45RA and CD45RC in peripheral blood lymphocytes.

动物处死后留组织、抗凝血及血清,进行以下检测:(1)原子吸收法测血清锌浓度;(2)测胸腺、脾脏脏器重量并与大鼠体重比较,计算脏器指数;(3)HE染色对胸腺、脾脏进行病理观察;(4)原位末端标记法测胸腺、脾脏中淋巴细胞的自发凋亡,并通过图像分析进行比较;(5)逆转录聚合酶链式反应检测凋亡调控基因bcl-2、bax mRNA在免疫器官中的表达;(6)免疫组化方法检测信号转导蛋白p56〓在免疫器官中的表达;(7)流式细胞术分析外周血淋巴细胞中CD4+、CD8+、CD45RA+及CD45RC+CD4+、CD45RC-CD4+细胞的数量和比例。

Positive staining of oxytocin and vasopressin were in the cytosol of the neurons and the former gave less intensity,many positive varicosities for vasopressin were also noticed in neurite.

催产素的免疫阳性产物主要在细胞核周围的胞浆即核周质内,而加压素的免疫阳性物质除了在核周质内有很强的反应外,在突起内也可见很强的免疫反应。

This work could be very helpful for understanding the immune balance, providing a new link between innate immunity and adaptive immunity, and increasing outcome of immuno therapy against tumor and virus infection.

通过本研究能够有利于理解免疫系统的平衡,尤其是获得性免疫对天然免疫的影响,这为肿瘤和病毒感染的免疫治疗以及移植排斥反应的控制具有重要意义。

The results of pharmacological assays, together with the structural characterization of the derivatives, indicate that immunomodulatory activity of glucan derivatives not only depends on the glycosyl residue linkages and sugar chain conformation, but also is closely related to the nature of functional groups, degree of substitution and its distribution in a glycosyl residue and along the sugar chain.

免疫药理分析表明,不同结构和电荷特性的取代基的引入可以极大地改变原多糖的免疫调节活性,不同取代度的同一种取代基也可能具有完全不同的免疫调节效应。

Product color intelligent design and optimization techniques based on genetic andimmunity theory This paper introduces genetic and immunity theory into PCID study, establishes a genecoding principle based on product subassembly, constructs a fitness function of colorschemes according to SCCA model, applies genetic and immunity algorithm to simulate theradiation and convergence process of MT, at last it builds a product color design model.Experiments prove that this method can design and optimize color schemes on its own.

5基于遗传与免疫理论的产品色彩方案生成与优化技术把基因遗传和生物免疫理论引入产品色彩智能设计中,提出以产品组件为基本进化单元的基因编码方法,根据形色耦合美度模型构造了色彩方案适应度函数,综合应用遗传算法与免疫算法模拟色彩设计复合思维的发散和聚敛过程并构建了色彩创新模型,算例表明该模型能解决产品色彩方案的自动生成与优化问题。

In recent years, there has been a shift from the perception of dendritic cells solely as inducers of immune reactiity to the iew that these cells are crucial regulators of immunity, which includes their ability to induce and maintain tolerance.

近年来,人们对于树突状细胞的概念从单一的作为免疫反应的激活者,转换到它们是免疫调节的关键细胞,其中包括它们能够诱导并维持免疫耐受。

Feinberg and fellow researchers determined that in sooty mangabeys, these dendritic cells do not signal as intense an alarm as they should when SIV attacks; thus, these important cells do not become activated during the initial stages when SIV infects.

范伯格和其他研究人员发现,当猴免疫缺陷病毒来袭,乌白眉猴体内的这些树突状细胞没有对强烈的免疫报警信号作出反应;因此,在猴免疫缺陷病毒感染的初始期,这些重要的并没有被激活。

It is suggested that six OMPs ofV.parahaemolyticus ompV, ompW, ompK, ompU, psuA and pvuA, are immunogenicduring in vivo infection, and may be of great significance for vaccine development.Especially, fish group immunized with recombinant ompK achieved a high protection of90%. For the wide expression of this conserved protein among vibrio species, ompKmust be paid enough attention for vaccine development against vibriosis.

研究结果显示了6种副溶血弧菌外膜蛋白ompW、ompV、ompK、ompU、psuA和pvuA具有良好的免疫原性,是宿主免疫应答的保护性抗原;尤其是ompK单个蛋白免疫组获得90%的保护率,由于该蛋白是弧菌中广泛存在的保守性蛋白,极有可能作为制备亚单位疫苗等高效弧菌疫苗的候选抗原。

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