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This is the website of the international ImMunoGeneTics information system, which is a high-quality integrated knowledge resource specializing in immunoglobulins, T cell receptors, major histocompatibility complex and related proteins of the immune system of human and other vertebrate species.

这是国际免疫遗传学信息系统的网站,它是一个高质量的综合资源信息系统,专门收集有关免疫遗传学、T细胞感受器、成人组织联合体相容性和人类及其他脊椎动物免疫系统的有关蛋白质等方面的信息。

Description: This is the website of the international ImMunoGeneTics information system, which is a high-quality integrated knowledge resource specializing in immunoglobulins, T cell receptors, major histocompatibility complex and related proteins of the immune system of human and other vertebrate species.

网站描述:这是国际免疫遗传学信息系统的网站,它是一个高质量的综合资源信息系统,专门收集有关免疫遗传学、T细胞感受器、成人组织联合体相容性和人类及其他脊椎动物免疫系统的有关蛋白质等方面的信息。

Immunologist Stephen Holgate of the University of Southampton in the United Kingdom says the results suggest the immune system in allergic patients is somehow out of balance, with overactive allergy-related immune cells.

英国南安普敦大学的免疫学家Stephen Holgate说,这一结果建议,过敏患者的免疫系统有失平衡,有过于活跃的与过敏有关的免疫细胞。

In this paper, the ability and mechanism of antibacterial and immune defense ofChinese shrimp was studied using cytological, biochemical, molecular biological andproteomic methods. A sensitive and stable antibacterial and lysozyme assay methodswere selected. The effect of Vibrio anguillarum and laminarin (a kind of beta-1,3-glucan) on the immune ability of haemolymph of Chinese shrimp was analyzed.The changes of total haemocyte counts, antibacterial ability, lysozyme activity andlysosome membrane stability were detected.

本文采用细胞学,生物化学,分子生物学和蛋白质组学等技术,对对虾的抗菌能力和免疫防御机制进行研究,筛选了灵敏稳定的抑菌和溶菌检测方法;并对灭活鳗弧菌和海带多糖(laminarin,一种B-1, 3 葡聚糖)免疫诱导后的中国明对虾血细胞数目,血淋巴的抑菌活力,溶菌能力,溶酶体膜的稳定性进行分析;对两种重要免疫因子溶菌酶和精氨酸激酶进行克隆和表达分析。

The experimental result shows:1 acupuncture and moxibustion on DU4 and RN4 can lighten inflammationreact , suppress the inflammation course, DU4 has the best result.2 IL-2 is the important factor of participating the immune respondence.Acupuncture and moxibustion can increase IL-2 content in the blood , thusstrengthen the immune function of the organism .3 acupuncture end moxibustion can raise β-EP content of lower thalamus ,hypophysis , lymph gland. it proves that acupuncture and moxibustion can stimulateand accelerate compound、store 、process 、shifting utility of β-EP content; andstrengthen the immune regulating function of the organism, acupuncture function isstrong rapidly, moxibustion function is slow and gentle, the regulating action powerof moxibustion has close relations with choice of the point . The possible reason isthat y whether acupuncture and moxibustion bring into play their regulating actionthrough different way of neural body fluid.4 The DU4、RN4、FEI point influence rule apply on change of β-EP content ofabove-mentioned organism.

实验结果显示:1 针灸命门和关元穴能减轻炎症反应,抑制炎症过程,命门穴效果最好。2IL-2 是参与免疫应答的重要因子,而针灸能增加血中 IL-2 含量,从而增强机体的免疫功能。3 针刺和艾灸可以升高下丘脑、垂体、淋巴结β-内啡肽含量,说明针灸可以刺激并加速β-内啡肽含量合成、储存加工和转移利用;增强机体的免疫调节功能,针刺作用迅速强烈,艾灸作用缓慢温和,艾灸的调节作用强弱还与穴位的选择有密切关系。

Objective: With umbilic blood from the mature newborns, to screen CpG-ODN, which can markly boost up the immunity response, from some designed CpG-ODNs; to compare the effect of CpG-ODN on the lymphopoiesis of umbilic blood from the premature, mature newborns and the peripheral blood from the adults; to observe the infulence of CpG-ODN on the immune function of the pregnant mices and their newborns, the immune-inhibited and aged mices.

目的:设计含非甲基化胞嘧啶和鸟嘌呤的寡聚脱氧核糖核苷酸,以期用足月新生儿脐血筛选出具有较强免疫增强作用的CpG-ODN;比较CpG-ODN对新生儿脐血和成人外周血单个核细胞的增殖效应;观察CpG-ODN对孕鼠及其新生鼠、免疫抑制鼠和老年鼠体液免疫功能的影响。

In order to develop a safe and effective immunoadjuvant to enhance the immunity and resistance of animals against infection, a novel CpG Oligodeoxynucleotides containing 11 CpG motifs was synthesized and inserted into the VR1012 plasmid, designated as VR1C. Then the recombinant VR1C was entrapped with Chitosan nanoparticles prepared by the method of ionic cross linkage, and employed to inject muscularly 3-weeks old Kunming mice; the blank VR1012 packed with CNP and saline were used to inoculate mice as the control groups. 28 days after inoculation, all mice were orally fed with 0.4ml 2x108CFU/ per mouse virulent hemorrhagic enteritis E. coli to challenge the resistance against infection.

为研制安全高效免疫调节剂增强动物免疫抗病能力,本实验设计合成含11个C pG基序的寡聚核苷酸,重组构建含CpG的VR1012质粒(VR1C);制备壳聚糖纳米颗粒包裹重组质粒(CNP-VR1C),肌注接种3周龄昆明小白鼠,设壳聚糖包裹空质粒和生理盐水对照组;接种后28天口服大肠杆菌攻毒观察小鼠天然免疫的变化和对强毒感染的抵抗力,Sandwich ELISA测定血清免疫球蛋白和白细胞介素含量。

The blood IgG and IgA level of new soldiers is significantly lower than that of control,But the IgM level is higher than that of control.Conclusion It suggest that old soldiers' paratroop stress is normal,the high stress can be lessen by training.

新兵在跳伞应激状态下免疫功能受抑制,但老兵免疫能力没有下降,某些免疫指标还有增高,表明老兵跳伞应激的反应是适度的,严重的跳伞应激可通过多次的训练而得以减轻。

Allabove indicated that the more antitumor ability of PELs was not theirmount,perhaps,but their quality.

以上这些说明微环境中一定水平IL-2的存在能使肿瘤的细胞免疫应答速度加快,免疫细胞获得杀伤能力所需时间短并伤百分率高,从而使在这种微环境中肿瘤细胞的生长明显受到抑制,同时也说明mIL-2〓诱导的PEL抗肿瘤能力,并非是通过免疫细胞数量上的增加来实现。

From occurrence and development mechanism, this article considers that the prevention and treatment for pyemia after severe empyrosis includes full body fluid anabiosis, early gastro-intestinal tract feeds, preventing intestinal tract endotoxin shifting, cutting the scab as soon as possible, eliminating necrosis, applying the antibiotic reasonably, immunity recuperation, maintaining the cellular immunity function, enhancing organism nutrition support, multi-organ function protection and improving organism prognosis.

本文通过对脓毒症的发生发展机制的阐述,认预防和治疗严重烧伤脓毒症全面的临床措施包括:快速、充分的体液复苏治疗和预防烧伤休克;早期胃肠道营养,以防止肠道内毒素移位;尽早切痂,清除坏死组织,封闭创面,合理应用抗生素,预防感染;免疫调理提高机体免疫能力,维护细胞免疫功能;加强机体营养支持治疗和多器官功能的保护,改善机体预后。

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