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Through all this test analyse Pathogenicity and Immunological status of ALV-J Inner Mongolia strain, the result showed the infected chickens began to have pathological change of Myelcytomatosis at 3-week: the main pathological changes of acidophile myelocyte were found in bone marrow and between cardiac muscle fibers,and there were many granules in the hyalotome.This kind of oncocyte proliferated in every tissue at different amount, but the cells that proliferated in bone marrow, cardiac muscle fiber, oarium were much more than other tissue, and they often developed neoplasma. At same condition,there were no abnormalty advent in control group, In immunological aspect: the increase of lymphokine and ANAE positive cells showed cell-mediated immunity was strengthend during antineoplastic infection; the emergence of ALV-J antibody of ELISA suggest there was humoral immunity exist at the same time.

结果显示:脾脏PCR检测结果表明1、2两实验组均有阳性病例出现,而对照组全部为阴性,说明实验鸡体内已有ALV-J内蒙株感染;接种病毒后3周龄开始出现骨髓细胞瘤病的病理变化:肝脏、脾脏有程度不同的肿大,镜下观察,骨髓内最早出现了与骨髓细胞相似、形态基本一致的大型圆形或椭圆形、胞核较大多为椭圆形、胞浆内含有大量嗜酸性圆形颗粒的髓细胞样瘤细胞增生,随后通过血流瘤细胞可转移到肝脏、心肌、卵巢或睾丸等组织并形成肿瘤性病灶,而对照组没有出现明显病变;免疫状态方面:以脾脏淋巴因子和ANAE阳性细胞增多说明细胞免疫在抗肿瘤感染过程中增强,ELISA检验实验鸡抗体出现阳性的结果表明同时也存在着体液免疫。

These pathways are essential for the vertebrate immune system to recognize and clear RNA virus with different strategies, which are integral parts of innate immune response and directly affect later-stage acquired immunity.

它们利用不同的细胞信号转导机制诱导先天性免疫反应,主要参与脊椎动物细胞识别和清除RNA病毒的原发抗感染过程,是机体先天免疫系统的一种重要反应机制,直接影响后续适应性免疫系统的作用。

The effect of the specific inhibitor cibacron blue of GSTs and antiparasitic drugs albendazole, praziquantel and artesunate on the activities of recombinant GSTM, GST1 and GST2 was evaluated.

研究目的解析三个胞质GSTs的基因结构及其特点,克隆三个胞质GSTs基因,鉴定原核表达的重组GSTs的免疫反应性、免疫原性、催化活性及其免疫定位和抑制剂、常用抗寄生虫药对催化活性的影响。

Lymphocyte blastogenesis and T lymphocyte population were analysized 1 d after the LPS administration,gene expression of IL-2 and IFN-γ was quantified by RT-PCR technology.

注射LPS使肉仔鸡发生了以细胞免疫为主的应激反应,皮质酮和T3水平、T4/T3比值及细胞因子mRNA表达量均能作为衡量免疫应激的敏感指标;免疫应激是相对于正常状态而言的,就其本身来说,尚无法衡量程度的高与低。

In addition, some of the failure of infectious coryza vaccination was due to the quality of vaccine and administration, and also some was due to the emergency of serotype B Haemophilus paragallinarum.

另外大多数鸡场的免疫失败是由于免疫效果不良所致,但也有相当一部分鸡场的免疫失败是由于B血清型的出现引起的。

Calf thymosin fration 5 (THF 5), prepared by modified Goldstein method, was given to 7 patients with acute acquired immunodeficiency diseases, including 1 fulminant Japanese B encephalitis associated with respiratory failure: 1 fulminant infectious hepatitis associated with hepatic coma; 1 chronic active hepatitis associated with peritonitis; 1 systemic lupus erythematosus associated with herpes zoster: 1 severe heat-exhaustion associated with deep coma, bacteriemia, and decubitus ulcer: 1 chronic granulocy...

本组7例急性T细胞免疫功能缺陷病人,经用小牛FHF_后,临床症状及实验室检查初步说明,该制品具有一定的改善患者细胞免疫功能状态和抗病毒、霉菌感染的作用。本文所采用的小牛THF_是在Goldstein氏的提取方法基础上进行了改进,分子量在15,000以下,免疫电泳分析显示没有牛血清白蛋白的大分子物质,脐带血玫瑰花结测定存在活性。由于本组病例尚少,还有待进一步探讨。

Molecular biology molecular genetics and cell biology to promote the development of molecular immunology immunogenetics and immune biology the formation of new branches so that people at the molecular level on the structure and function of the immune system have a more understanding.

分子生物学、分子遗传学以及细胞生物学的发展促进了分子免疫学、免疫遗传学以及免疫生物学等新的分支学科的形成使人们在分子水平上对免疫系统的结构与功能有了更加深刻的熟悉。

Although this is very uncommon, it may happen in patients who have decreased immune system function, referred to as "immunosuppressed" or "immunocompromised."

尽管这种情况非常少见,但它还是可能在免疫功能低下的病人中出现的,例如免疫抑制或是免疫受损的病人。

The journal also publishes commentaries on topics of general interest to cancer immunologists, such as heat shock proteins, cancer immunosurveillance, adjuvants, and immunological escape mechanisms, as well as the origins and history of the field by invited.

杂志同时刊载肿瘤免疫学家感兴趣的主题的评注,例如热激蛋白,肿瘤免疫监测,辅助剂,和免疫逃逸机制,以及特约这一领域的起源和历史。

Pedal swelling induced by 1% agar in mice, dermal c apillary hyper-permeability induced by histamine in rats were used to evaluate the anti-inflammatory of Kangning granules, and the clearance rate of intraveno us ch arcoal particles was used to study its effect on non-specific immunologic funct i ons. Serum haemolysin level and the number of antibody secretory cells in spleen were determined to assess its effects of specific immunologic functions.

运用小鼠足跖肿胀和大鼠皮肤毛细血管通透性实验观察其对炎症反应的影响;用碳粒廓清实验评价其对非特异性免疫功能的影响、测定免疫小鼠血清抗体水平和脾细胞抗体分泌细胞数量以评价感冒康宁颗粒对特异性体液免疫功能的影响。

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