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Chuankezhi injection, the main product of Perfect Set is the second sort new medicine authorized by State Food and Drug Administration. It is made of pure Chinese tradition medicine Epimedium Herb and Morinda officinalis. Chuankezhi control and cure effectively of asthma by regulate body and cell's immune. Since widely used in clinic, it was proved that Chuankezhi has the significant effects and non-toxic side effects for that it is the first choice for respiratory disease and for regulating body's immune system.

公司主要产品喘可治注射液是由国家食品药品监督管理局批准的国家二类新药,喘可治是纯中药制剂,主要由淫羊藿和巴戟天经高科技精炼提取而成,是通过调节机体免疫与细胞免疫达到治疗和有效控制哮喘复发的中药制剂,该药上市以来,经临床广泛应用,疗效显著,无毒副作用,是治疗呼吸系统疾病和调节机体免疫能力的首选药物。

In addition to phagocytose pathogens,macrophages can also induce adaptive immunity to perform more specific responses.

巨噬细胞在人体的免疫反应当中扮演著十分重要的角色;其除了能吞噬病原菌之外,还能诱发后天免疫系统,产生更专一的免疫反应。

Objective To study the statement of immunoreaction of c Jun and functional recovery of spinal cord injury in rats after fetal spinal cord transplantation.Methods Experimental rats were divided into two groups:spinal cord hemisection injury combination with transplants of FSC to injured site group,and spinal cord injury that received gelfoam pledgets group.On the lst,3th,7th,14th and 28th day after operation,6 animals in each group at each time phase,were observed for their function recovery with the methods of praxiology and electro physiological examination,the animals were then sacrificed for the observation of the statement of c Jun reaction by immnochemistry method and computer image analysis system was used for quantitative analysis.

目的:研究大鼠胚胎脊髓移植后能否影响,c-Hun免疫反应的表达和脊髓损伤后大鼠功能的恢复,方法;将动物分为脊髓半切洞损伤加胚胎脊髓移植组和单纯脊髓板切洞损伤加明胶海绵填塞组,每个时相点每组6只动物,术只1,3,7,14和28天,应用行为学和电生理检查观察大鼠功能恢复情况,应用免疫细胞化学方法,c-Jun免疫反应的表达,采用计算机图像分析技术,进行定量分析。

Orange-spotted grouper is a benthic protogynous marine fish with sex inversion. It is one of the most important culturing fish in the southeast of Asia. As in other vertebrates, its growth is mainly controlled by growth hormone . Few data are available concerning the regulation of GH in grouper. In this paper, the regulation of growth hormone release from pituitary of orange-spotted grouper and its mRNA level was determined by radioimmunoassay and RNase protection assay.

中文题名斜带石斑鱼生长激素分泌及其基因表达调控的研究副题名外文题名 Regulation of growth hormone and its gene expression in orange-spotted grouper,Epinephelus coioides 论文作者冉雪琴导师林浩然学科专业水生生物学研究领域\研究方向学位级别博士学位授予单位中山大学学位授予日期2003 论文页码总数140页关键词生长激素基因表达石斑鱼馆藏号BSLW /2003 /Q959 /39 应用分子克隆技术,构建了斜带石斑鱼生长激素(Growth hormone,GH)基因重组质粒,在大肠杆菌细胞中获得高效表达,亲和层析纯化斜带石斑鱼GH融合蛋白做为抗原,免疫家兔制备特异性抗体,通过酶联免疫实验、放射免疫测定、离体脑垂体静态孵育和液相杂交/核糖核酸酶保护试验及化学发光检测技术,研究了斜带石斑鱼GH分泌及其mRNA表达的调控机制,对于斜带石斑鱼的生长、繁殖、人工养殖等具有重要意义。

The successful cloning and expression of yak IL2 gene is putatively useful for the development of novel immunopotentiator to raise the immunity of yak against various infectious pathogens and the immuno-protective efficacy of vaccinations.

本实验成功克隆了犛牛IL2基因,其原核表达产物具有显著的免疫活性,这为研制新型免疫增强剂来提高犛牛对各种疾病的抵抗力,增强犛牛疫苗的免疫保护率奠定了基础。

Results: The Fos-like immunoreactive neurons distributed mainly in the spinal trigeminal subnucleus caudalisipsilaterally and medullary visceral zone (MVZ,including nucleus tractus solitarius,ventrolateral medulla and the reticular formation between the first two),ln the sections processed for double staining of Fos and TH immunohisto chemistry, numerous Fos-LI neurons showed also TH- like immunoreactivity in their cytoplasm(Fos-TH cells)in MVZ.

结果:Fos样免疫反应神经元主要分布在同侧三叉神经脊束核尾侧亚核、双侧延髓内脏带(孤束核、腹外侧区及二者之间的网状结构)。在抗Fos 和抗酪氨酸羟化酶的双重免疫染色切片上,见到延髓内脏带内许多Fos阳性神经元的胞浆同时呈TH样免疫反应(Fos-TH双重阳性细胞)。

The central complex isprominent. The beetle showed notable 5-HT-like immunoreactivity throughout the wholebrain, which was also strongly labelled by TPH antibody, with the pattern matching that of5-HT. 5-HT-like positive fibers were resolved in all areas of the brain, among which thelamina and suboesophageal ganglion showed the most remarkable dark brownimmunostaining. While, all major neuropil regions, in general, showed low level backgroundafter TPH immunostaining for TPH mainly existing in cytoplasm. The number of 5-HT-likeimmunoreactive neurons was relatively small but possessed extensive varicose arborizations.

免疫组化结果显示,异色瓢虫脑系统呈强5-HT免疫反应,表现为稳定的反应模式;其脑系统对鼠抗TPH单克隆抗体同样呈显著的免疫阳性反应,且反应模式与5-HT一致。5-HT能神经元多为切向神经元,数目相对较少,呈两侧对称分布,主要位于视叶与侧前脑之间、前脑背方及咽下神经节处,其阳性纤维呈明显的静脉曲张状,投射区域较广泛。

To attain more comprehensive understanding of flounder immune system, it is necessary to characterise and localise lymphoid cells within the different lymphoid organs. Use polyclonal antibody or monoclonal antibody as a tool will benefit this kind of study.

制备针对免疫球蛋白的多克隆或单克隆抗体,作为研究工具,对免疫器官中产生抗体的组织和细胞进行定位,可以了解免疫器官在防御疾病过程中是如何发挥作用的,以便对应用疫苗奠定理论基础。

Allogeneic and syngeneic fresh bone, autolyzed antigen-extracted bone, bone matrix gelatin, demineralized bone matrix were implanted into the muscle pouch of mice, at different times after implantation, the immunological, histological and alkaline phosphatase assay were conducted. The results revealed that all four kinds of allogeneic implants activated specific cellular and humoral immune responses, most notably in fresh bone group, the AAA, BMG and DBM inhibited the proliferation of the lymphocytes in vitro and BMG had the most powerful inhibiting action, allogeneic AAA, BMG and DBM might induce heterotopic osteogenesis in vivo, however, there were obvious difference in ALP and histomorphometry between allografts and isografts.

在小鼠肌肉内植入同种异体或同系新鲜骨、自消化抗原去除骨、骨基质明胶、脱钙骨基质,术后免疫学、碱性磷酸酶、组织学检查发现:4种同种异体植入物均可引发特异性细胞免疫反应和体液免疫反应,其中以新鲜骨移植引发的免疫反应最为显著;自消化抗原去除骨、骨基质明胶、脱钙骨基质在体外具有抑制淋巴细胞增殖的作用,骨基质明胶对淋巴细胞增殖的抑制作用最显著;同种异体与同系4种植入物在体内成骨活性有显著差异;自消化抗原去除骨、骨基质明胶、脱钙骨基质均有异位诱导成骨活性,其中骨基质明胶骨诱导活性最佳。

Many studies of immune mechanisms in radiation-attenuated cercariae immuned mice models show that the high protective immunity is mediated by CD4+T cell.

在辐照致弱尾蚴免疫小鼠等动物模型中的免疫机制研究表明,辐照致弱尾蚴诱导所产生的高保护力主要是由CD4+T细胞介导的细胞免疫。

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