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In summer of the result of the experiment, we can suspect the traditional Chinese medicine BaoTai Decoction may urge Th2 cytokine (IL-4, IL-10)'s express level to increase and Th1 cytokine (IL-12, IFN-γ)'s express level to decrease through adjusting Th cell's network equibrium, then prohibit maternal -fetal immune system to assault Fetus, which is good to maintenancing cyesis.

综合本实验结果,推测中药保胎汤可能通过双相性调节母-胎界面Th细胞网络的平衡,促使保护母-胎免疫功能Th2型细胞因子(IL-4,IL-10)增加,损伤母-胎免疫Th1型细胞因子(IL-12,IFN-γ)抑制,从而阻止母胎免疫系统对胎儿的攻击,利于妊娠维持。

Compared with control,①the mean tumor weight of H22 of SXKA Granules three dose groups were decreased significantly(P.01,P.05),and the mean inhibition rates of SXKA Granules 20、10 g/kg dose groups were above 30%;②the mean tumor weight of S180 of SXKA Granules three dose groups were decreased significantly(P.01),and the mean inhibition rates of SXKA Granules 20、10 g/kg dose groups were above 32%;③the mean tumor weight of EAC of SXKA Granules three dose groups were decreased significantly ( P.01, P.05),and the mean inhibition rates of SXKA Granules 20 g/kg dose groups were above 38%;④the mean tumor weight of Lewis carcinoma of SXKA Granules three dose groups were decreased significantly(P.01, P.05),and the mean inhibition rates of SXKA Granules 20、10、5 g/kg dose groups were above 36%;⑤the mean tumor weight of W256 of SXKA Granules three dose groups were decreased significantly ( P.01, P.05),and the mean inhibition rates of SXKA Granules 20、10 g/kg dose groups were above 32%;⑵Compared with control,SXKA Granules 20、10 g/kg dose groups had extended the survial time of the P388-bearing mice respectively(P.01),and the mean prolong rates of SXKA Granules 20、10 g/kg dose groups were above 50%;⑶Compared with S180-bearing group, SXKA Granules 20、10 g/kg dose groups could increase the weight of thymus and spleen, Spleen index and thymus index were increased, SXKA Granules 5 g/kg dose group could increase thymus index(P.05);⑷As Compared with control group, SXKA Granules 20、10 g/kg dose groups could improve mouse serum half hemolysis value depressed by transplanted tumor dramatically(P.01), which revealed the SXKA granules could improve the mouse humoral immunity system;⑸SXKA Granules 20 g/kg dose group could increase of englobe indexαon S180-bearing mice remarkably(P.01), which indicated the SXKA Granules could improve their cellular immunity system.

对荷W256大鼠,生兴克癌冲剂20、10、5 g / kg三组的平均瘤重明显低于对照组(P.01,P.05),生兴克癌冲剂20、10 g / kg组的平均肿瘤抑制率均大于32 %;⑵与空白对照组相比,生兴克癌冲剂20、10 g/ kg能显著地延长移植小鼠白血病P388小鼠的存活天数(P.01),生兴克癌冲剂20、10 g/ kg对荷白血病P388小鼠生命延长率均在50%以上;⑶与S180荷瘤组相比,生兴克癌冲剂对荷瘤鼠的免疫器官重量、胸腺指数和脾指数有一定的提高趋势,其中生兴克癌冲剂5 g / kg组对荷瘤小鼠的胸腺指数有一定的提高作用(P.05);⑷与S180荷瘤组相比,生兴克癌冲剂20、10 g /kg组可提高由荷瘤引起的小鼠血清半数溶血素值的降低(P.01),表明其可提高荷瘤小鼠体液免疫功能;⑸与对照组相比,生兴克癌冲剂20 g /kg组可提高荷S180肉瘤小鼠的免疫吞噬系数α值(P.01),表明其可提高荷瘤小鼠细胞免疫功能。

With the development of immunology, it has been discovered that HSP is related with the immunological dysfunction, which manifests hypoactivity of cellular immunity and hyperactivity of humoral immunity.

随着免疫学研究的进展,人们已明确本病的发病与免疫功能紊乱有关,表现为细胞免疫功能低下,体液免疫处于高反应状态。

Theoretically, its calculation complexity is studied, while it is tested empirically by learning multi-samples generated randomly. The comparative analysis and applications show it has some merits of rapid searching and good clustering effect. B3. An immune network optimization algorithm with information feedback, which can solve special complex function optimization problems with high dimensions which objective functions are formed by summing multi-subobjective ones, is constructed based on the clone selection principle and the immune network regulation of the idiotype immune network.

为了对免疫系统中抗体如何学习抗原特征的整体行为有一定的认识,从单个抗体识别抗原及多个抗体并行识别抗原的特征出发,利用免疫应答的相关原理及免疫细胞的免疫功能设计了适合于批量样本聚类的抗原特征学习算法,理论上分析了其计算复杂度,获得了此算法中的关键参数与其搜索性能的关系;应用上,该算法通过对实际的多样本学习,获得了搜索速度快及聚类效果好的优点,比较分析表明这种方法是可行的和有效的。

Lymphocyte shuttling between blood and lymphy organ is the substance to keep immune stabilization, perform their immune defence and immune surveillance, If there have markedly change on lymphocyte function and amount, which can be thought immune disorder, which associated with clinical disease.

穿梭在血液与淋巴器官中的淋巴细胞是维持机体免疫稳定,执行免疫防御、免疫监视功能的物质基础。

The IM-AFSA is based on immune memory and mediatory mechanism; the IV-AFSA is based on vaccination.

IM-AFSA是一种基于免疫记忆和调节机制的免疫人工鱼群算法;IV-AFSA是一种基于疫苗接种的免疫人工鱼群算法。

The convergence of the SOIO has been proved and the optimization quality of the MOIO has been tested by comparing with some multiobjective genetic algorithms.

证明了免疫单目标优化方法的收敛性,将免疫多目标优化方法与几种多目标遗传算法进行了比较,免疫多目标优化方法显示了一定的优越性。

Orange-spotted grouper is a benthic protogynous marine fish with sex inversion. It is one of the most important culturing fish in the southeast of Asia. As in other vertebrates, its growth is mainly controlled by growth hormone . Few data are available concerning the regulation of GH in grouper. In this paper, the regulation of growth hormone release from pituitary of orange-spotted grouper and its mRNA level was determined by radioimmunoassay and RNase protection assay.

应用分子克隆技术,构建了斜带石斑鱼生长激素(Growth hormone,GH)基因重组质粒,在大肠杆菌细胞中获得高效表达,亲和层析纯化斜带石斑鱼GH融合蛋白做为抗原,免疫家兔制备特异性抗体,通过酶联免疫实验、放射免疫测定、离体脑垂体静态孵育和液相杂交/核糖核酸酶保护试验及化学发光检测技术,研究了斜带石斑鱼GH分泌及其mRNA表达的调控机制,对于斜带石斑鱼的生长、繁殖、人工养殖等具有重要意义。

①Rat MSC and VSMC were cultured and identified, respectively. MSC were labeled with DAPI firstly, and then co-cultivated with VSMC. The changes of morphology and ultrastructure of co-cultured cells were observed. Immunfluorescence analysis was performed by using monoclonal antibodies against specific antigen.②We established the regulatable system in two steps: a stable MSC line expressing rtTA has been constructed and characterized firstly by transfected with pUHD 17-1hyg and then selected by hygromycin B; in a second step, this line was used for trandfer the AT2R gene to MSC to get the well establishing double stable MSC lines;③The expression of AT2R regulated by doxycycline was evaluated by western blot;④The MSCs were transduced into rat carotid arteries with regulatable AT2R gene after the establishment of rat carotid balloon injury restenosis model. The intimal/medial area ratio were measured by digital analysis system.

研究方法:(1)密度梯度离心法及胶原酶消化法分别培养原代大鼠MSC及VSMC,细胞共培养并行免疫荧光化学染色和透射电镜观察超微结构;(2)组成受Dox调控的哺乳动物表达系统的四种成分的转化、扩增及提纯并酶切鉴定;(3)采用常规分子生物学方法连续两个回合转染体外培养的MSC,并分别采用发光计检测不同细胞克隆萤光素酶活性改变以及RT-PCR方法检测AT2R目的基因mRNA表达情况,根据各个细胞克隆受Dox调控表达的程度,选择低背景、高诱导表达AT2R的细胞系,作为双重稳定MSC细胞系;蛋白免疫印迹法观察该细胞系在Dox调控下AT2R表达的时相性、持续性及在不同浓度Dox调控下的表达情况;(4)建立大鼠颈动脉球囊损伤动物模型,将双重稳定MSC在术中导入血管,分别于14 d、28 d进行病理切片,检测可调控AT2R对新生内膜增生的影响;采用RT-PCR免疫组织化学免疫荧光等技术观察AT2R基因在新生内膜中的表达以及细胞外基质成分表达的改变,TUNEL法检测血管组织中细胞凋亡的变化情况。

The immuno-protective activity of the vaccine was determined by CTL induction and tumor growth inhibition in vaccine-immunized syngenic mice.

以重组质粒免疫C5 7BL/ 6小鼠,检测诱发的特异性CTL活性;将免疫后的小鼠用TC - 1肿瘤细胞攻击,观察免疫保护效果。

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However, as the name(read-only memory)implies, CD disks cannot be written onorchanged in any way.

然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

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A single payment file can be uploaded from an ERP system to effect all pan-China RMB payments and overseas payments in all currencies.

付款指令文件可从您的 ERP 系统上传到我们的电子银行系统来只是国内及对海外各种币种付款。