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The immunoregulation activity of SPG-1 mainly existed in the part of sugar chain, but keeping its molecular structure intact had some effects on its immunoregulation activity; SPG sulphation had reducing effects on the immunoregulation of SPG-1, whereas, after medium and low acetification of SPG, the immunoregulation of SPG was enhanced. Conversely after high acetification, the immunoregulation of SPG-1 decreased, that is, after introducing sulfuric and acetic acid base in SPG-1, its immunoregulation changed. All of these indicated the structure of SPG-1 was closely connected with its immune activity.⑤.

甘薯糖蛋白SPG-1的免疫调节活性主要在其糖链部分,但保持分子结构的完整性对其免疫调节的活性有一定的作用;甘薯糖蛋白硫酸化对甘薯糖蛋白SPG-1的免疫调节有降低作用,而中、低度乙酰化后,可提高甘薯糖蛋白的免疫调节作用,高度乙酰化后则降低其免疫调节作用,即甘薯糖蛋白引入乙酰基和硫酸基团后,其免疫调节活性发生了改变,这些均表明了甘薯糖蛋白的结构与其免疫调节活性有密切的关系。

The reason is the tumor cells escape the immunosurveillance whose mechanism is very complex. In general, the explanation is based on two aspects, one is that the tumor cells can passively escape the host immunosurveillance when the host immnue state is low and another is tumor cells can actively secrete factors to down-regulate immune function.

肿瘤逃避免疫监视的机制非常复杂,但总体上可从宿主免疫状态及肿瘤细胞等方面来解释,在宿主免疫状态低下时,肿瘤细胞可以被动地逃避免疫监视,但是肿瘤细胞也能主动地释放一些活性物质,下调免疫杀瘤作用,该作用主要通过两个途径,即对免疫细胞功能的调节和免疫细胞数量的调节。

RESULTS:After pinealectomized mice was irradiated WBI with 75 mGy X-rays,we found levels of plasma corticosterone increased obviously,and the effects of the proliferative reaction of splenocytes to ConA and spontaneous proliferation of thymocytes was found to be decrease. But injecting melatonin into pinealectomized mice or putting melatonin in the cultured cell,its immune functions might renew the enhancement.CONCLUSION:Melatonin of pineal gland might regulate the immunoenhancement induced by low dose radiation.MeSH Pineal body; Melatonin; Radiation; Corticosterone; Immunity,cellular

低剂量辐射(low dose radiation,LDR)全身照射(whole body irradiation,WBI)可引起免疫系统的兴奋效应,主要表现在以T淋巴细胞功能激活为主的细胞免疫和体液免疫功能的增强并可提高机体的抗瘤作用[4,5],在LDR诱发免疫功能增强的同时伴有下丘脑-垂体-肾上腺皮质系统功能下调等神经内分泌功能的改变,神经内分泌对免疫系统的调节可能是LDR免疫兴奋效应发生的必要条件,松果腺MLT与辐射免疫兴奋效应的关系值得研究。

The treated group was revaccinated with 5μg YRHBV while the control group with 10μg blood-derived HB vaccine, their anti-HBs response was determined 1,12,24 months after revaccination.

结果显示:用5μg重组酵母乙肝疫苗进行再免疫能取得良好的抗-HBs应答,不论再免疫前抗-HBs水平高低,再免疫后能呈现免疫回忆反应。

With rarefied the albumen after is vaccine of oily emulsion of immune former preparation immune egg chicken, the result makes clear, CCK albumen can cause immune reaction inside gallinaceous body, tenability of antibody of the CCK in serum of chicken of the egg after strengthening immunity and yolk is in higher level.

以纯化后的蛋白为免疫原制备油乳剂疫苗免疫蛋鸡,结果表明,CCK蛋白可在鸡体内引起免疫反应,加强免疫后蛋鸡血清和卵黄中CCK抗体可维持在较高水平。

As an immunomodulator NO may play a role like a double-edged sword since it expresses both in immuonchalleged and immunosspresed states. 2. After received external stimulus the morphology of ependyma of SFO could be changed and varied with time course, particularly its cellular apoptosis do occur and earlier than the ordinary areas of the brain. 3. Astrocytes in SFO could express cFos protein induced by LPS, suggesting the cells may maintain homeostasis in the brain in a longer period and modulate immune state of the brain. 4. As a CVO, SFO may sense changes of blood-bearing immunosignals earlier and instantly response to them, thus as one of windows of the brain SFO do take part in immunomodulation within the brain.

通过我们的实验结果我们可以得出这样一些初步的结论:1、一氧化氮作为免疫调质参与了机体免疫,它既能在免疫激发状态下又可在免疫抑制状态下进行表达提示,NO在脑内免疫调节中的作用可能是双向的。2、穹窿下器的室管膜形态在接受外界刺激后,随着时间的变化而不同,扫描电镜下的凋亡形态虽需进一步证实,但室管膜细胞确实发生了凋亡,并且穹窿下器发生的较早。3、穹窿下器内的星形胶质细胞在给予大肠杆菌后确实可以表达c-fos蛋白,并可能通过自身的激活来较长时间的维持体液的动态平衡,调节脑内免疫状态。4、穹窿下器作为感受性室周器官之一,能够较早的感受血携免疫信息的改变并及时作出反应,可能作为外周免疫信息进入脑内的窗口之一来参与脑的免疫调节。

According to the above evaluation of immuno-epidemiology of RSA, RSA may be etiologically classified into lack of materno-fetal immuno-recognition, materno-fetal inappropriate immuno-recognition, and disorder of materno-fetal immuno-recognition.

根据RSA免疫流行病学分析,RSA的病因可以分类为:母-胎免疫识别低下型、母-胎免疫识别过度型及母-胎免疫识别紊乱型。

The objective was to determine the effects of active immunization of T-3-BSA in Rom cockerels, 400 cockerels were divided into 4 groups, group 1,2 and 3 were treated with T-3-BSA on different dose(0.2,0.4,0.8mg/mI respectively),within each group,there were 5 treatments following different vaccination schedules, group 4 served as controls. Every injection of immunogen was conducted on different sites around the neck, and the datas were measured at week 11,15,19, combs,wattles,body weight,serum T concentration,carass traits and testicular development and histology were studied in order to find out the most reasonable vaccination schedule and the most possible mechanism in the H-P-G axis of T.

本试验测定了睾酮—3—牛血清白蛋白(T-3-BSA)主动免疫对公鸡性腺与冠垂发育及雄激素水平的影响。400只罗曼蛋用雏公鸡除随机取25只作对照组外,另375只随机分成3大组,每大组125只再随机分成5小组,每小组25只,3大组分别使用0.2mg/ml、0.4mg/ml和0.8mg/ml的T-3-BSA免疫注射,每大组的①②③小组分别于3、6、9周龄免疫注射,④小组于3周龄首次免疫,6周龄加强免疫,⑤小组于3周龄首次免疫,9周龄加强免疫。

After biology immunity mechanism is thoroughly analyzed, diploid immune algorithm is put forward based on the integration of biology immunity principle and biology genetic theory.

由于模拟生物免疫系统功能的免疫算法具有解决复杂工程问题的潜力,同时也存在容易陷入局部最优平衡态和进化后期搜索停滞不前的缺陷,在深入分析生物免疫系统机理之后,将生物免疫原理和生物遗传理论集成到免疫算法中,提出了双倍体免疫算法。

Specific antibody of the turbot fries could be detected in a week after injection immunization and maintained high level for at least 6 weeks, with the highest of 1382,the relative percentage survival was 50%;The level of the specific antibody of the vaccinated brood turbots was low but maintained stable and kept long time.

其中大菱鲜鱼苗免疫鱼抗体效价在免疫后6周内一直呈上升趋势,最高达1382,4周后测得的免疫保护率为50%;大菱虾亲鱼免疫后抗体效价产生较慢,效价水平较低,但下降缓慢,免疫3个月后仍维持抗体效价54。

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However, as the name(read-only memory)implies, CD disks cannot be written onorchanged in any way.

然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

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A single payment file can be uploaded from an ERP system to effect all pan-China RMB payments and overseas payments in all currencies.

付款指令文件可从您的 ERP 系统上传到我们的电子银行系统来只是国内及对海外各种币种付款。