免疫抑制的

The invention relates to the isolation and preparation of an active fraction from plant Cuminum cyminum, its further purification and standardization as chemically defined entity with their intended use as drug bioavailability enhancer for the drugs belonging to therapeutic categories such as antimicrobial, antifungal, anti-viral, antitubercular, antileprosy, anti-inflammatory, antiarthritic, cardiovascular, antihistaminics, respiratory distress relieving drugs, immunosuppressants, anti-ulcerogenic, anti-cancer, CNS drugs, corticosteroids, nutraceuticals in compositions to be administered orally/parenterally, topically, inhalations, rectally, vaginally in human beings and/or veterinary conditions.

本发明涉及植物孜然芹中的一种活性级分的分离和制备，进一步的纯化以及它作为化学确定实体的标准化，和它作为治疗类药物的生物利用率增强剂的特定用途，这类药物包括如抗微生物剂、抗真菌剂、抗病毒剂、抗结核药、抗麻风病药、抗炎药、抗关节炎药、心血管类药、抗组胺药、呼吸窘迫缓解药、免疫抑制剂、抗溃疡药、抗癌药、CNS药、皮质甾类药、营养制品，它们以组合物的形式通过口服/肠胃外，局部，吸入直肠，阴道施用于人和/或兽医学病症中。

Malignancy following enteric bladder augmentation arose in 4.5%(7/153) of our patients and was associated with coexisting carcinogenic stimuli (prolonged tobacco/chronic immunosuppressive exposure), or alternatively with the inherent risk of malignancy existing with bladder exstrophy.

我们研究的接受肠道膀胱扩大术的患者有4.5 ％（ 7 / 153 ）发生了恶性肿瘤，恶性肿瘤的发生与共存的致癌刺激（长期烟草/慢性免疫抑制剂的服用）有关，或者与膀胱外翻固有的恶性肿瘤发生风险相关。

The book comprehensively reviews the molecular and cellular biology of the most important microbial toxins with a focus on recent advances in the field, covering topics such as toxin ADP-ribosylation of proteins, toxin inhibition of protein synthesis, modulation of actin cytoskeleton, cytolethal distending toxins, cell-damaging/pore-forming toxins, clostridial neurotoxins, toxins of the immune system, streptococcal and staphylococcal toxins, anthrax toxins, Shiga toxin, Yersinia toxin, mycotoxins, and the regulation of toxin expression, as well as the potential of microbial toxins in bioterrorism.

该书全面评论了最重要的微生物毒素的分子与细胞生物学，重点是这一领域中的最新进展，主题包括蛋白质毒素ADP核糖基化，毒素抑制蛋白质合成，肌动蛋白细胞骨架的调控，细胞致死增加毒素，细胞损伤/孔状毒素，梭菌属的神经毒素，免疫系统的毒素，链球菌和葡萄球菌毒素，炭疽毒素，Shiga毒素，Yersinia毒素，毒枝菌素，和毒素表达调节，以及生物恐怖中微生物毒素的潜在可能性。

The results were listed as follows:"Cumiansan" had certain promotion and enhancement to the thickness of foot-plate in DTH, CD4+/CD8+T cell ratio in peripheral blood of the normal and the immunosuppressive mice as well as the normal mice's blood serum TNF-a content, the ultra-fine powder remarkably surpassed the commonly cribble.

结果表明，&促免散&对正常和免疫抑制小鼠足趾变态反应、外周血CD4~+/CD8~+T淋巴细胞亚群的比例以及正常小鼠的血清TNF-α的含量均有一定的促进和提高作用，但与粉体的粒度和剂量有关，微粉低剂量即可达到与粗粉中高剂量相当的效果。

By the examination of MRI, histopathology, and the caculation of survival rate and percentage of patency, the viability of graft status of autograft tracheas wrapped in one-side sternomastiod muscule flap and two-side sternohyoid muscle flap based on different pedicle, effects of neck muscle associated with bFGF on length of autografts, and limit of warm ischemia time on tracheal allograft before cryopreservation were evaluated in rabbits.

肿瘤、先天性疾病、炎症或其他原因引起的气管狭窄，切除病变气管行气管端端吻合术是最理想的方法。而长段气管切除术后，则需要行气管重建。20世纪以来随着免疫学的发展，肾脏、心脏等脏器移植已在临床应用成为可能，人们注意到气管移植的重要性。因此，气管移植成为长段气管缺损重建的方向，其面临的主要问题是移植气管的再血管化、免疫抑制、供体的来源与保存等。

Moreover, MCTs are rapidly hydrolysed and oxidised to fatty acids and ketones which can be readily utilized and storage is very limited.

一些体外的实验显示LCT会使白血球的趋化和移动性受损而降低白血球的活性，也会抑制免疫球蛋白的合成和吞噬细胞肿瘤坏死因子之产生。

because the sugar cortical hormone class medicine has very strong anti-function and so on inflammation, anti-allergy, antitoxin, anti-shock, immunity suppression, thus caused it to become the basic unit medical establishment certain doctors' multi-purpose panaceas, no matter any got sick all uses, thus created the sugar cortical hormone class medicine in basic unit abusing.light creates the nonessential pain and the economic loss for the basic unit patient; heavy endangers the patient life.

由于糖皮质激素类药物具有很强的抗炎、抗过敏、抗毒素、抗休克、免疫抑制等作用，因而使其成了基层医疗机构某些医生的万能灵丹妙药，不管什么病都用上，从而造成糖皮质激素类药物在基层的滥用。轻者给基层患者造成不必要的痛苦和经济损失；重者则危及病人生命。

Methods All mice in the experimental groups were immunosuppressed by given different concentrations of dexamethasone phosphate added in drinking water throughout the experiment. The recovery and purity of the oocysts obtained using different purification methods was compared. The infectivity of the oocysts obtained from the same origin but different animals and different purification methods in a bovine fallopian tube epithelial cell culture system was studied.

在饮水中添加不同浓度的地塞米松对人工感染小鼠进行免疫抑制，探讨获得最多卵囊数的药物添加量；比较不同纯化方法得到的卵囊回收率和纯度；探讨来自不同动物、不同纯化方法的卵囊在牛输卵管上皮细胞培养系统的感染情况。

The level of ABAb negatively correlated with sgpl30 concentration (r=0.375, P.05). Conclusion IL-6 signal transduction might be involved in Tourette's syndrome to lead the function enhancement and start cascade of feedback inhibition, because of elevated levels of sIL-6R, sgpl30, ANAb and ABAb in serum. Autoimmune-related injuries may potentially explain the pathogenesis of the disease.

TS患者依赖IL-6信号传导的生理功能上调和反馈抑制的网络机制启动；自身免疫相关的损伤机制均可能参与了疾病发生发展的病理生理过程。

Fungi are playing a more and more important role in infective diseaes with the increasing of using immunocompromised drugs, organ transplantation and AIDS.

随着免疫抑制剂的大量运用、器官移植的增多、艾滋病等在全球的肆虐，当今世界疾病谱和致病菌正在发生深刻的变化。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。