免疫抑制的

Glucocorticoid is a kind of steroid compound synthesized and secreted by adrenal cortex fascicular zone, which is a key factor of the hypothalamus-hypophysis-adrenal gland-immune axis.

糖皮质激素(glucocorticoid，GC)是下丘脑-垂体-肾上腺轴的关键分子，除具有重要的生理作用外，还具有很强的免疫抑制作用，临床上被广泛用于自身免疫性疾病的治疗。

Although the deelopment of relatiely non-toxic immunosuppressie or tolerance-inducing regimens will be required to justify clinical trials using pig organs, recent adances in our understanding of the biology of xenograft rejection and zoonotic infections, and the generation of alpha1,3-galactosyltransferase-deficient pigs hae moed this approach closer to clinical application.

尽管用猪的器官去验证临床试验需要相对无毒的免疫抑制剂或致耐的方法，但随着近来我们对异种移植排斥生物学及动物传染病感染的深入理解，以及α1，3 半乳糖转移酶缺陷猪的产生，异种移植更接近临床应用。

Serum creatinine elevations were noted in a proportion of patients, most of whom also had multiple risk factors for renal damage such as concomitant use of nephrotoxic immunosuppressants.

血清肌苷酸上升在一部分患者身上被注意到，他们中的大多数对于肾脏损害有成倍的风险例如对于损害肾脏的免疫抑制剂伴随物的使用。

Results Complications of deep white candidiasis infection inside the hospital mostly took place among patients suffering from chronic respiratory diseases, malignant tumors and nosohemia,accounting for 59.09%.Infection was in direct proportion with the length of hospitalization.The chief factor leading to infection was the long-term use in large doses of wide-spectrum antibiotics,especially the use of the third-period cephalosporins,which are wide in spectrum and strong in killing bacteria.White candidiasis infection results from the composite action of multiple dangerous factors. Ofthose infected,40.91%used hormone and 11.36% used immunosuppressive agents as well as radiotherapy and chemotherapy. The application of trauma examination and curing also created conditions for the occurrence of infection.

结果 发生医院内部白色念珠菌感染多系慢性呼吸系统疾病、恶性肿瘤和血液病患者，占59.09%；感染与住院时间成正比；广谱抗生素大剂量、长时间应用，特别是选择广谱、杀菌力强的第三代头狍菌素类是致感染的主要因素；白色念珠菌感染是多种危险因素综合作用的结果，感染者使用激素的占40.91%，使用免疫抑制剂及放疗化疗的占11.36%，实施插入性操作及各种介入性治疗为感染创造了条件。

For raising the accuracy of the diagnasis ancl treatinemt of ALH We realised of 86 patients with diagnosis of Autoimmune liver disease, strictly defined by the criteria for diagnosis of autoimmune hepatitis or the results of liver histology, and tested its biochemical, serological, histological results. AIH patients were main women female 75 cases, male 11 cases, main in 40 - 60 years old ,AIH characterized by a flare of ALT, AST, elevated immunoglobulin G,γ-immunoglobulin: ALP, IgG, and presence of antinuclear antibody (81.5%); moderate or severe periportal or periseptal lymphocytic piecemeal necrosis.

为提高对自身免疫性肝炎的诊治水平，采用国际自身免疫性肝炎小组新修订的描述性诊断标准和计分系统，对符合诊断的患者进行临床、生化、病理特点分析。86例AIH患者，女75例，男11例，高发年龄为40～60岁，其中Ⅰ型80例(93.020k)，Ⅱ型3例(3.49％)；Ⅲ型3例(3.49％)；肝功能生化检查表现为肝炎样改变；实验室检查主要表现为高γ球蛋白血症，高IgG、ALP、γ-GT及甘油三酯增高，81.5％患者抗核抗体阳性：病理改变以界板性肝炎，浆细胞浸润为主，78％的患者对免疫抑制剂治疗效佳。

The hepatocytes which were injected into thymus could survive more than 2 weeks after injection and appeared to be irregular hepatic cells cords and sinusoid in shape, and severe vacuolar degeneration in 3 weeks.

本实验在未用任何免疫抑制剂的情况下，肝细胞胸腺内注入后1周、2周，显微镜下见植入胸腺内的肝细胞已生长出不规则的肝索及肝窦样结构。3周时的胸腺内植入的肝细胞仍存活，但空泡变性明显。

Furthermore, our data suggest that inhibition of EGF-C modulates immune cell infiltration and their function, which might be critical in tumor immunity.

而且，我们的数据还显示，EGF-C的抑制改变了免疫细胞的渗透性和功能，这可能在肿瘤免役中是很关键的。

The affinity constant of E1-McAb reacting with coated complete antigen was 8.2×10^8L/mol. Biotin-streptavidin complex was used for the determination of E1. The calibration curve of free E1 covered a range of 10～10 000 pg/mL.

以生物素化的羊抗鼠免疫球蛋白及辣根过氧化物酶标记的链亲和素为标记体系，通过竞争抑制的方式测定游离的雌酮，结果表明：雌酮在10～10000pg/mL内呈线性关系。

Objective To study the effects of berbamine and batiolun on LDH metabolizability in the process of increasing leukocyte.Methods Enzyme biochemical techniques is used to study the effect of berbamine and batiolˉun in the process of inceasing leukocyte and also to study the effect of LDH metabolizability.

目的 研究小檗胺和鲨肝醇升高白细胞作用及对细胞内LDH的代谢的影响方法采用酶细胞化学方法，对两药物在治疗由免疫抑制剂环磷酰胺所致的白细胞减少症时，对乳酸脱氢酶活性的影响进行了比较观察。

In a third study using organ donor stem cells to create a chimerism, two patients (50%) were successfully weaned after 12 months but returned to low-dose immunosuppressive therapy five months later.

在第三项研究显示，利用器官捐赠者的干细胞制成嵌合体，有两名患者(50%)在12个月的治疗后，成功的进行戒断，但在5个月后，又恢复到低剂量的免疫抑制治疗中。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了