免疫抑制的

AIM: To study the effects of paecilomyces cicadidae total polysaccharides on the immune function and free radical scavenging of tissue, in immunosuppressed rats.

目的：观察蝉拟青霉总多糖对免疫抑制大鼠组织器官免疫功能调节和自由基代谢的影响，探讨其对免疫抑制大鼠组织器官的免疫调节和抗衰老作用。

AIM: To study the effects of paecilomyces cicadidae total polysaccharides on the immune function and free radical scavenging of tissues in immunosuppressed rats.

目的：观察蝉拟青霉总多糖对免疫抑制大鼠组织器官免疫功能调节和自由基代谢的影响，探讨其对免疫抑制大鼠组织器官的免疫调节和抗衰老作用。

Autoimmunity hypothesis of schizophrenia figures schizophrene has a certain degree of immunological functional disturbance,Hypothalmu- pituitary- adrenal axis can produceimmunosuppression. Hydrocortisone,the production of HPA axis,serve as important medium of immunosuppression, so we presume that hydrocortisone possibly induce immunological dysfunction of schizophrene.

精神分裂症的自身免疫假说认为精神分裂症患者存在一定程度的免疫功能低下，而下丘脑-垂体-肾上腺轴功能紊乱被认为是引起免疫抑制作用的主要机制之一，其中皮质醇是免疫抑制作用的重要介质，因此我们推测精神分裂症患者可能存在有皮质醇含量增高有关。

OBJECTIVE: To alert the medical community about this unusual association of infectious diseases in a healthy patient without sickling or immunosuppression.

目的：警告医学界在没有镰状红细胞改变或免疫抑制的健康病人，这种罕见的感染性疾病的联合。

the Chinese herbs-Qiang ji kang have the bidrectional immune regulation function to the cellular immune responses of the immunosthenic and Immunorepressive mice . it can decrease the humoral immune responses of the Immunorepressive mice. It have anti-inflammafory and abirritation

中药强脊康对机体亢进和抑制的细胞免疫功能起到双向调节作用，能抑制亢进的体液免疫功能；并对急慢性炎症具有一定的抑制作用，镇痛作用明显、持久，但起效慢。

As a functionally and phenotypically distictive T cell subpopulation,CD4+CD25+ regulatory T cells are anergic and retain their ability to suppress antigen-driven response of CD4+CD25- cells in a contact-dependent manner or through a way of secreting immunosuppressive cytokines such as IL-10 and TGF-β.

CD4+CD25+调节性T细胞是一群表型和功能特异的T细胞亚群，具有免疫无能和免疫抑制两大特性，通过细胞直接接触或分泌抑制性细胞因子发挥对CD4+CD25-T细胞的抑制作用。

Injection of rhIL-2 (200,100,50,25,12. 5 ku/kg) can inhibit mouse ear swelling, especially when dosage is 25～50 ku/kg. Injection of rhIL-2 (25 ku/kg) can inhibit rat plantar swelling. The function of mononuclear macrophage system was strengthened by hypodermic injection of rhIL-2( 100 ku/kg) once a day for 9 days. The decrease of mouse delayed-type hypersensitivity reaction induced by cyclophosphamide was extenuated by hypodermic injection of rhIL-2(50 ku/kg) once a day for 6 days. IL-2 has anti-inflammatory effects and immunomodulatory effects when administered in certain dosage.

RhIL-2注射液，剂量为20，10，5，2.5，1.25万u/kg时，对小鼠鼠耳肿胀模型有抑制作用，其中剂量为2.5～5万u/kg时，抑制率最大；剂量为2.5万u/kg时，对大鼠足拓肿胀模型有显著的抑制作用；rhIL-2注射液每日sc用药剂量为10万u/kg，连续给药9d后，可以明显增强小鼠单核吞噬细胞功能；rhIL-2注射液每日sc用药剂量为5万u/kg，连续给药6d后，可明显减轻由免疫抑制剂引起的小鼠迟发性变态反应降低的强度。rhIL-2在一定剂量范围内可以起到抗炎和免疫调节作用。

In addition to the common effect of supplementing qi, YiQiYangYin Fang has unique clinical application in exercise-induced fatigue disease because of its function of reinforcing yin; YiQiBuShen Fang is used for treating senescence diseases by reason of its function of invigorating kidney.

本课题以中医药理论为指导，依据益气养阴方和益气补肾方的功效与应用，结合目前运动性疲劳和衰老的产生机制等方面的研究进展，采用现代药理学研究方法，观察益气养阴方和益气补肾方对环磷酰胺致小鼠免疫抑制的抵抗作用及对小鼠常压耐缺氧和断头后张口喘气时间的抗应激能力，同时分别采用运动性疲劳大鼠模型和自然衰老大鼠模型进一步探讨益气养阴方抗运动性疲劳机制及益气补肾方抗衰老机制。

Baicalin could inhibit the initial-period and mid-period activation of mouse T lymphocytes stimulated by Con A or PDB,which suggests that baicalin have the inhibitory effect on signaling pathway of T lymphocytes activation and be a potential effective immunoinhibitory agent.

结论黄芩苷能够明显抑制多克隆刺激剂Con A或PDB诱导的T细胞早期和中期活化，且呈明显的量效关系。提示黄芩苷在T细胞活化过程的信号转导中有抑制作用，从而可以通过抑制T淋巴细胞的活化，发挥免疫抑制作用，是一种潜在的免疫抑制剂。

Adoping the simple and easy anthology to gather the unit to gather urine of 5 hours measures, Watch different series of urine quantitative changeization .(2) Experiment of immunity: Adopted CY methods copy immunity to repress the little rat pattern, To divide randomly small healthy white mice originated from kunming into normal contrast group ,pattern group, Fulin group, Guizhi group,Fulin and Guizhi group (Two medicine are according to 1 : 1、2: 1、 1: 2、 4: 3 the proportion compose ).Be total to 8 groups . To observed Fulin and Guizhi different combinition adjust the repressing small mice's spleen and thymus, Ascertaining by measuring little rat phagocyte the gobbleing uprate and serum IL-2 -* TNF — a 's content.

2免疫实验采用环磷酰胺法复制免疫抑制小鼠模型，健康昆明种小鼠随机分为正常对组、模型组、茯苓组、桂枝组、茯苓与桂枝配伍组(两药按1：1、2：1、1：2、4：3比例进行组合)共8组，观察茯苓桂枝药对及其各配伍组对免疫抑制小鼠脾、胸腺的影响，测定小鼠吞噬细胞吞噬率及血清IL-2、TNF—α含量。

Fancy gold-plated dangling earrings with facetted White Opal crystals.

花式镀金悬垂耳环与facetted白欧泊水晶。

This essay chooses the study aim from biology teachers in middle school in Shi Jiazhuang which tells us that most of the middle school biology teachers in Shi Jiazhuang have the"burnout", lower successfulness, individualize.

本文选取石家庄市初中生物教师作为研究对象，运用问卷调查的方法对石家庄市初中生物教师职业倦怠的现状进行调查，调查结果发现，石家庄市初中生物教师这一群体普遍存在职业倦怠，情感枯竭程度偏高，成就感偏低，去个性化程度最为严重。