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The results showed that IFN-γ immunoreactive structures widely distributed in CA1, CA2, CA3 and indusium griseum, which indicates IFN-γ have definite influence on physiological function of hippocampus.

结果表明,IFN-γ免疫反应主要分布于海马CA1、CA2、CA3区,有少量分布于灰被,齿状回。这为海马具有免疫调节功能的观点提供了新的证据。结合文献,推断IFN-γ在海马-下丘脑-垂体-肾上腺的免疫调控中起主要作用。

The nonspecific immunotherapy with immunopotentiator——IL-2, TNF, BCG in treatment of cancer has the advantages of simple manip- ulation、inexpensiveness and easy popularization compared with the AIT or gene therapy.

与过继免疫或基因治疗相比,应用免疫增强剂——IL-2、TNF、BCG等非特异性免疫治疗肿瘤具有操作简单、费用低,易推广等优点。

Secondly, through the filariasis immune experiment, people improve that the skin is wiped with the levamisole liniment at regular intervals instead of preparing the bacterin for inoculability, levamisole actions of resisting the virus and infection are exerted without the disease when inoculating the pathogeny, and the specificity immune protection is obtained under the pathogeny action, the immune preventive intention is reached just as injecting the bacterin.

二是,经丝虫病免疫实验证实,不用制苗接种,通过左旋咪唑搽剂定期皮肤涂药,在接种病原时,发挥左旋咪唑抗病毒、抗感染作用而不发病,并在病原作用下,获得特异性免疫保护,就像注射疫苗一样达到免疫预防的目的。

Results In the major salivary glands of the fetus from 14-week to 32-week, the epithelial cells of striated and interlobular ducts showed NT-3 immunoreactivity. The immunoreactive intensity in the three major salivary glands was similar and it had no obvious chang from 14-week to 32-week.

结果 14~32周胎儿大唾液腺内纹状管和小叶间导管上皮细胞呈NT-3免疫阳性反应。3种大唾液腺中NT-3的免疫染色强度相似,且在胚胎发育的14~32周,免疫反应强度未见明显变化。

Methods: Chitosan/pVAX1-pZP3α nanoparticles was prepared and administered into each experimental mouse on weeks 0,3 and 6 by intranasal and intravaginal respectively, whereas chitosan without DNA was given to control.

制备pVAX1-pZP3α壳聚糖纳米微粒,分别滴鼻和阴道免疫10只BALB/c 小鼠,对照组免疫不含DNA的壳聚糖,第3周和第6周分别加强免疫一次,ELISA法检测小鼠血清、阴道冲洗液中抗pZP3 IgA和IgG抗体

In this paper, the ability and mechanism of antibacterial and immune defense ofChinese shrimp was studied using cytological, biochemical, molecular biological andproteomic methods. A sensitive and stable antibacterial and lysozyme assay methodswere selected. The effect of Vibrio anguillarum and laminarin (a kind of beta-1,3-glucan) on the immune ability of haemolymph of Chinese shrimp was analyzed.The changes of total haemocyte counts, antibacterial ability, lysozyme activity andlysosome membrane stability were detected.

本文采用细胞学,生物化学,分子生物学和蛋白质组学等技术,对对虾的抗菌能力和免疫防御机制进行研究,筛选了灵敏稳定的抑菌和溶菌检测方法;并对灭活鳗弧菌和海带多糖(laminarin,一种B-1, 3 葡聚糖)免疫诱导后的中国明对虾血细胞数目,血淋巴的抑菌活力,溶菌能力,溶酶体膜的稳定性进行分析;对两种重要免疫因子溶菌酶和精氨酸激酶进行克隆和表达分析。

Twenty-six eyes which appeared rejection after allograft penetrating keratoplasty between April 2003 and April 2004 in Shandong Shi'erming Eye Hospital were collected, including 16 males and 10 females, 9 cases were repeated relapsing viral keratitis, 8 cases were traumatic posterior corneal leucoma, 5 cases were corneal decompensation caused by various intraocular surgery, 2 cases were congenital leucoma, and 2 cases had other symptom. The rejection occurred at 2 month to 2.5 years after operation. Among them 19 cases were transferred to our hospital and asked adding traditional Chinese therapy because western medicine was ineffective in other hospital.

选择山东施尔明眼科医院2003-04/2008-04接诊的同种异体穿透性角膜移植后发生排斥反应病例26例,男16例,女10例,反复发作病毒性角膜炎9例,创伤性后角膜白斑8例,各种内眼手术引起角膜失代偿5例,先天性角膜白斑2例,其他2例,上皮型免疫排斥反应、基质型免疫排斥反应、内皮型免疫排斥反应均有,排斥反应发生在术后2个月~2.5年,其中19例是外院西药治疗无效而转入山东施尔明眼科医院要求加用中医治疗。

The product is used both medicament box of microplate luminometer and software of analyze a management system,which can be used many aspects in medically and immunity analysis.

该产品与发光免疫分析试剂盒和专用的免疫数据分析管理系统配合使用,能够满足各类临床及基础医学领域内高灵敏度定量和定性免疫测试的要求。

The experimental result shows:1 acupuncture and moxibustion on DU4 and RN4 can lighten inflammationreact , suppress the inflammation course, DU4 has the best result.2 IL-2 is the important factor of participating the immune respondence.Acupuncture and moxibustion can increase IL-2 content in the blood , thusstrengthen the immune function of the organism .3 acupuncture end moxibustion can raise β-EP content of lower thalamus ,hypophysis , lymph gland. it proves that acupuncture and moxibustion can stimulateand accelerate compound、store 、process 、shifting utility of β-EP content; andstrengthen the immune regulating function of the organism, acupuncture function isstrong rapidly, moxibustion function is slow and gentle, the regulating action powerof moxibustion has close relations with choice of the point . The possible reason isthat y whether acupuncture and moxibustion bring into play their regulating actionthrough different way of neural body fluid.4 The DU4、RN4、FEI point influence rule apply on change of β-EP content ofabove-mentioned organism.

实验结果显示:1 针灸命门和关元穴能减轻炎症反应,抑制炎症过程,命门穴效果最好。2IL-2 是参与免疫应答的重要因子,而针灸能增加血中 IL-2 含量,从而增强机体的免疫功能。3 针刺和艾灸可以升高下丘脑、垂体、淋巴结β-内啡肽含量,说明针灸可以刺激并加速β-内啡肽含量合成、储存加工和转移利用;增强机体的免疫调节功能,针刺作用迅速强烈,艾灸作用缓慢温和,艾灸的调节作用强弱还与穴位的选择有密切关系。

Objective: With umbilic blood from the mature newborns, to screen CpG-ODN, which can markly boost up the immunity response, from some designed CpG-ODNs; to compare the effect of CpG-ODN on the lymphopoiesis of umbilic blood from the premature, mature newborns and the peripheral blood from the adults; to observe the infulence of CpG-ODN on the immune function of the pregnant mices and their newborns, the immune-inhibited and aged mices.

目的:设计含非甲基化胞嘧啶和鸟嘌呤的寡聚脱氧核糖核苷酸,以期用足月新生儿脐血筛选出具有较强免疫增强作用的CpG-ODN;比较CpG-ODN对新生儿脐血和成人外周血单个核细胞的增殖效应;观察CpG-ODN对孕鼠及其新生鼠、免疫抑制鼠和老年鼠体液免疫功能的影响。

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