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儿茶酚

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Results Eleven compounds were isolated and identified as:quercetin(1),kaempferol(2),quercitrin(3),protocatechuic acid(4),gallic acid(5),protocatechuic acid ethyl ester(6),ethyl gallate(7),vanillic acid(8),1,5,7-trihydroxyl-3methylan...

结果得到11个化合物,分别鉴定为:槲皮素(1)、山柰酚(2)、槲皮苷(3)、原儿茶酸(4)、没食子酸(5)、原儿茶酸乙酯(6)、没食子酸乙酯(7)、香草酸(8)、1,5,7-三羟基-3-甲基蒽醌(9)、琥珀酸(10)、5-羟甲基糠醛(11)。结论化合物6、7、9、11为首次从该属植物中分离得到。

To further study the chemical constitutes of lipophilic active parts, we prepared Alc95% and Alc50% according to original literature. 20 compounds were isolated by using macroporous resin, silica gel, polyamide, Sephadex LH-20, Rp-18, preparative TLC and preparative HPLC chromato-graphy. The structures of them were elucidated by means of physical and chemical properties, modern spectroscopic analysis techniques—UV、IR、 EI/MS、ESI/MS、〓H-NMR、〓C-NMR、DEPT、HMQC、HMBC. They are nine anthraquinones: chrysophanol (95-1), physcion (95-2), emodin (95-5), aloemodin (95-7), rhein (50-1), sennoside A or B (50-6),ω-hydroxylemodin (95-10), chrysophanol-8-0-β-D-glucoside (95-12), aloemodin-ω-0-β-D-glucoside (95-13); three phenanthaquinones: tanshinone ⅡA (95-3), cryptotanshinone (95-6), tanshinone Ⅰ(95-4); one isoflavone: 7, 3'-dihydroxyl-5' methoxyisoflavone (95-14) and protocaechuic aldehyde (95-9), protocaechuic acid (95-11), astragaloside Ⅳ(50-4), amygdalin (50-5), 2, 3, 5, 4'-tetrahydroxylstilbene-2-0-β-D-glucoside (50-3),-catechin (50-2), cinnamic acid (95-8). Among them, 3'-dihydroxyl-5' methoxyisoflavone (95-14) is a new compound.

经过溶剂萃取、大孔吸附树脂富集、Sephadex LH-20精制、制备TLC及Semi-pre HPLC等手段从中分离了20个化合物,利用理化性质和波谱技术(UV、IR、EI/MS、ESI/MS、〓H-NMR、〓C-NMR、DEPT、HMQC、HMBC)相结合鉴定了它们的结构,分别为9种蒽醌类化合物:大黄酚,大黄素甲醚,大黄素,芦荟大黄素,大黄酸,番泻苷A或B,ω-羟基大黄素(ω-hydroxylemodin),大黄酚-8-0-β-D-葡萄糖苷(chrysophanol-8-0-β-D-glucoside),芦荟大黄素-ω-0-β-D-葡萄糖苷(aloemodin-ω-0-β-D-glucoside);3种菲醌类化合物:丹参酮ⅡA(tanshinoneⅡA),隐丹参酮,丹参酮Ⅰ(tanshinone Ⅰ);1种异黄酮:7,3'-二羟基-5'-甲氧基异黄酮(7,3'-dihydroxy-5' methoxyisofla-vone)以及原儿茶醛,原儿茶酸,黄芪甲苷(astragaloside Ⅳ),苦杏仁苷,2,3,5,4'-四羟基二苯乙烯-2-0-β-D-葡萄糖苷(2,3,5,4'-tetrahydroxylstilbene-2-O-β-D-g1ucoside),Z—儿茶素,桂皮酸。

This indicated effects of regulation on scenescence of fruit were through influencing the changes of internal ABA content. The relationship between different oxidative enzymes in the flesh and pericarp and ethanol accumulation in different maturity of 'brumal jujube' were investigated.

与果肉相比,冬枣果皮中含有较高的总酚、H_2O_2含量和较低的抗坏血酸含量;果皮中含有两种游离酚酸:儿茶酸、阿魏酸,显著低于果肉中的酚酸种类,贮藏末期果皮中的两种酚酸分别下降了80.36%和59.1%;而且果皮总酚含量与转红率呈显著负相关R=-0.88~(**,推测酚类物质的变化参与了冬枣果皮色泽变化。

MethodsIn the solvent of 1 mol/L NaOH, using the reaction of the water-soluble phenolic acidity in Radix Salviae Miltiorrhizae and the NaNO_2-Al(NO_3)_3, the total components of water-soluble phenolic acidity in Radix Salviae Miltiorrhizae injections and drip solution(calculated with protocatechualdehyde) were determined by colorimetric s...

方法利用丹参中水溶性酚酸类成分与亚硝酸钠和硝酸铝溶液在碱性条件下的显色反应,比色法测定该两种制剂中水溶性酚酸的总量。结果原儿茶醛在3.336~14.46mg/L范围内呈良好的线性关系,回归方程为:A=0.02777C+0.01279(r=0.9996),加样平均回收率为100.8%,RSD为0.96%。结论该法简便快速,结果准确,重现性好,可用于该制剂的质量控制。

Besides this function, the "Jinguihuishengyi" can lead to the discharge of catecholamine, and the neurolemma polarization, and then influence the permeability of the neurolemma.

此外,金匮回生液除释放乙酰胆碱的作用外,还能引起儿茶酚胺的释放,并通过作用轴突出引起神经膜极化,从而影响神经膜的通透性。

A conventional three-electrode system is fabricated to study electrochemical and enzymatic reaction between tyrosinase in the gold nanoparticles and catechol in acetonitrile.

结果:基于构建的新型酶电极,对儿茶酚的催化响应显示了良好的线性关系,该酶电极最大响应电流密度为23.6μA/cm^2,米氏常数为4.28mmol/L。

Chen (1995) Differential effects of chloral hydrate and pentobarbital sodium on a cocaine level and its catecholamine response in the medial prefrontal cortex: a comparison with conscious rats, J.

标题中译:以三氯乙醛及巴比妥钠盐麻醉下之大白鼠其内前额皮质区之古柯碱浓度及其引起儿茶酚胺浓度上升之关系:和清醒大白鼠相比较。

Substitute green tea for coffee and soda: it contains catechins known to inhibit cancer growth.

用绿茶代替咖啡和汽水,绿茶内的儿茶酚可以抑制癌细胞的生长

Alpha-2 agonists induced hypoxemia is an effect that is specific for ungulates and has neer documented in humans.

此外,Bissonnette[6]建议认为,胎儿和新生儿出现急性缺氧时的呼吸反应可被蓝斑核内的作用于α-2受体的儿茶酚胺所减弱。

Senior author Duska Dragun, MD, from the Department of Nephrology and Intensive Care Medicine, Charite University Hospital–Campus Virchow Clinic, Berlin, Germany, and colleagues in Berlin and in Melbourne, Australia, investigated whether the COMT variant with lower activity predisposes patients to acute kidney injury and prolonged vasodilatory shock after bypass surgery because of the increase in plasma catecholamines.

资深作者、来自德国柏林Charite大学医院校园Virchow诊所肾脏科的Duska Dragun医师与澳洲墨尔本及柏林的同事们研究COMT基因变异是否会降低病患接受绕道手术后,因为血中儿茶酚胺浓度上升,发生急性肾脏损伤与血管扩张性休克的机率。

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