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Already know, attention deficit hyperactivity disorder in children with urinary 3-A 4 Phenylethanol hydroxyl oxygen content decreased in cerebrospinal fluid homovanillic acid homocysteine decreased, and both are catecholamine metabolites.

已经知道,多动症患儿尿中3一甲4一氧羟苯乙醇含量减少,脑脊液中同型香草酸含量降低,而二者都是儿茶酚胺的代谢产物。

Tolcapone could greatly improve PD patients'motor function,especially in hypokinesia,muscle rigidity,and which could also improve patient's cognition ability.

儿茶酚 O位甲基转移酶抑制剂托卡朋能够改善PD的运动功能,尤其是运动减少和肌僵直,同时能改善患者的认知功能。

The results show that the interaction mode is mainly electrostatic interaction in the low concentration of dobutamine and adrenaline whereas intercalative binding plays a dominant role in their high concentration.

本文利用光谱和电化学方法研究了儿茶酚胺衍生物与小牛胸腺DNA之间的作用机制。

The safety of the Prescription was comfirmed by 〓Ca determination of transmembrane inflow. The tablet procedure was studied in such aspects, i. e. compressing method, the category and ammount of HPMC, binder and malactic with monofactorial test. Then Compound Danshen Sustained-release Tablet was made, which can release composition 12 hours continuously.

在缓释剂型研究实验中,采用钙拮抗作用确定了有效部位配比处方安全有效,采用丹参素和原儿茶醛的体外释放度作为评价指标,运用单因素方法筛选确定了亲水凝胶骨架片的压片方法、凝胶骨架材料种类与用量、粘合剂的种类、润滑剂的种类,优化形成了复方丹参缓释制剂处方,制成了l天2片缓释12h的复方丹参缓释片。

Manypharmacological experiments have been conducted to determine the effects of adrenergic agonistand antagonist of catecholamine receptors on Meretrix meretrix metamorphosis.

药理学实验分别采用了几种儿茶酚胺类受体的激动剂和抑制剂来处理幼虫,检验它们在幼虫变态过程中的作用。

A method for the determination of phenol and catechol in tobacco leaf by high performance liquid chromatography with methanol and 0.05 mol/L of monopotassium phosphate as mobile phase at a flow rate of 0.5 mL/min was described. Phenol and catechol were extracted from tobacco sample by distillation and solid phase extraction with Sep Park C 18 cartridge.

引 言挥发酚是烟草中一类重要的成分,它在烟草燃烧时直接进入烟气,大多有不好的气味,而且很难被掩盖;特别是苯酚和儿茶酚对呼吸系统有腐蚀作用和助癌作用,近年来逐渐引起了烟草化学工作者的注意〔1〕。

Thetotal amount of 13 kinds of acid methanol soluble phenolic substances in female plant leaves ofAcer negundo L.was also significantly higher than that in male plant leaves.

因为原儿茶酸、丁香酸、苯甲酸、肉桂酸、杨梅黄酮等组分的含量较高,复叶槭雌株叶片中13种酸性醇溶性酚类物质的总量普遍高于雄株(p<0.01)。

The disturbances of catecholaminergic neurotransmission have been implicated in the neuropsychiatric and cardiovascular diseases.

在患神经精神病和心血管疾病的患者中发现儿茶酚胺能传递失调,暗示ZNF191基因可能是这些疾病的发生或发展的相关基因。

The key points of diagnosis of pheochromocytoma were concluded as follow: a history ofparoxymal hypertension;an increased concentration of plasma catecholamines;131I-MIBG was a high sensitive and specific method with qualitative and orientative value.

综合本组病例的临床资料,诊断嗜铬细胞瘤的要点有:(1)病史中存在阵发性高血压的线索;(2)血中儿茶酚胺浓度增高;(3)131I-MIBG对诊断嗜铬细胞瘤具有高的敏感性和特异性,并兼有定位及定性诊断价值。

Based on relative literatures,this part has included five resesearch aspects as below.1 Fifteen compounds were isolated and purified by extraction,column chromatography,and their structures were determined on the basis of spectral analysis: acteoside(Ⅰ-1),isoacteoside(Ⅰ-2),crenatoside(Ⅰ-3),cistanoside F(Ⅰ-4),sinapoyl-4-O-β-D-glucoside(Ⅰ-5),adenosine(Ⅰ-6),β-siterol(Ⅰ-7),oleanic acid(Ⅰ-8), succinic acid(Ⅰ-9),caffeic acid(Ⅰ-10),protocatechuic aldehyde(Ⅰ-11),p-hydro xybenzyl alcohol(Ⅰ-12),β-daucosterol(Ⅰ-13),D-galacitol(Ⅰ-14),D-mannitol(Ⅰ-15).Ⅰ-4~15 were obtained from this plant for the first time,andⅠ-6,7,9,and 13 were isolated from Orobanche genus for the first time.2 The scavenging test of DPPH showed that most compounds have comparative antioxidant activity as L-ascorbic acid and part of them show better activity such as the O.coerulescens extract and phenylethanoid glycosides.Acteoside showed potent free radical scavenging effects with a median inhibition concentration of 25.6μg/ml.3 The anti-HBV activities of acteoside,isoacteoside and crenatoside were measured,and all of them showed suppressive activity on the expression of HBsAg and HBeAg in the HepG2.2.15 cell line.

本论文在文献调研基础上对紫花列当化学成分及生物活性进行了研究,并从免疫抗病毒角度探讨紫花列当中特征性成分类叶升麻苷的肝保护作用及其机制。1采用大孔树脂、硅胶和Sephadex LH-20等色谱技术对紫花列当进行系统的植物化学研究,从中分离得到19个化合物,利用UV和NMR等波谱手段及理化性质鉴定了其中的15个化合物,分别为类叶升麻苷(Ⅰ-1)、异类叶升麻苷(Ⅰ-2)、crenatoside(Ⅰ-3)、cistanoside F(Ⅰ-4)、sinapoyl-4-O-β-D-glucoside(Ⅰ-5)、腺苷(Ⅰ-6)、β-谷甾醇(Ⅰ-7)、齐墩果酸(Ⅰ-8)、琥珀酸(Ⅰ-9)、咖啡酸(Ⅰ-10)、原儿茶醛(Ⅰ-11)、对羟甲基苯甲酸(Ⅰ-12)、β-胡萝卜苷(Ⅰ-13)、D-半乳糖醇(Ⅰ-14)和甘露醇(Ⅰ-15除化合物Ⅰ-1、Ⅰ-2和Ⅰ-3外,其余化合物均为首次从该植物中分离得到。2)通过大孔树脂富集该药材有效部位苯乙醇总苷,并采用HPLC测得其所含特征性成分类叶升麻苷的含量可达80%以上。3DPPH自由基清除试验显示紫花列当提取物及其所含的苯乙醇苷类化合物均具有较好的抗氧化能力,其清除DPPH自由基能力接近于抗坏血酸。4采用卡介苗整体致敏、脂多糖离体攻击构建大鼠原代肝细胞免疫性损伤模型,在体外观察类叶升麻苷的保肝作用。

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