儿茶

ObjectiveTo establish an HPLC method for the determination of catechin in Compositae Catechu Capsules.

目的建立复方儿茶胶囊中儿茶素的含量测定方法。

Epigallocatechin gallate is the most active and studied of green tea's catechins.

表没食子儿茶素没食子酸酯是绿茶儿茶酚中活性最强，研究最为深入的物质。

Results:The contents of tanshinoneⅡA and protocatechuic aldehyde in alcoholic extract of raw products were the most.

结果：丹参酮ⅡA和原儿茶醛以生品醇提最高；丹参酮ⅡA以其生品水提最低，而原儿茶醛以白酒炙后水提最低。

A method based on capillary electrophoresis with electrochemical detection has been developed for the separation and determination of epicatechin, kaempferol, chlorogenic acid, 4-hydroxybenzoic acid, quercetin and protocatechuic acid in hawthorn for the first time.

首次采用毛细管电泳—电化学检测法同时测定山楂中的6种活性成分：表儿茶素，山奈酚，氯原酸，4-羟基苯甲酸，槲皮素和原儿茶酸的含量。

In chapter 6, a simple and rapid method for the simultaneous determination of three water-soluble compounds,β(3, 4-dihydroxyphenyl) lactic acid, protocatechuic acid and protocatechuic aldehyde, in radix Salviae Miltiorrhiza injection was firstly developed.

在第六章，我们首次建立了一种简单的、快速的同时测定丹参注射液中三种水溶性化合物丹参素、原儿茶酚和原儿茶醛的毛细管区带电泳法。

Results: Nine compounds were obtained from the ethyl acetate fraction of C. speciosa and were identified as methyl chlorogenate, 5-O-cafeoyl quinic acid butyl ester, quinic acid butyl ester, 5-hydroxymethyl-furan-2-carbaldehyde, triacontanoic acid,-epicatichin, 7,8-dihydroxy-coumanrin, protocatechuic acid ethyl ester, and protocatechuic acid.

结果：从皱皮木瓜的乙酸乙酯萃取部位分离鉴定了9种化合物，分别为绿原酸甲酯，5-O-咖啡酰基－奎宁酸丁酯，奎宁酸丁酯，5-羟甲基－2-糠醛，三十烷酸，-表儿茶素，7，8-二羟基香豆素，3，4-二羟基苯甲酸乙酯，原儿茶酸。

The volume of stimulant amino acid in the hypothalamic tuberal part of rat is dcreased,the volume of rejective amimo acid increased,the volume of Catecholamines drceased,the volume of the stimulant amino acid in spinal cord intermediolateralis,the rate of stimulant amino acid and rejective amimo acid,and the volume of Catechomamones dcreased,the volume of NE in spleen tissue dcreased,all of which means the irritability of sympathetic nervous circulus in spleen is restrained.

运动组大鼠下丘脑结节部兴奋性氨基酸含量下降，抑制性氨基酸含量上升，儿茶酚胺含量下降，脊髓中间外侧柱兴奋性氨基酸含量下降、兴奋性氨基酸/抑制性氨基酸下降、儿茶酚胺含量降低，脾组织内NE含量降低，提示有氧运动组大鼠的脾脏交感神经调节通路的兴奋性受到抑制。

Moreover, MeJA induced defense genes, such as pathogenesis-related proteins (PR2a), phenylalanine ammonia-lyase, BX9, and TPS. MeJA also increased DIMBOA and Vannillic acid content of leaves and roots significantly but leaf p－Hydroxybenzoic acid concentration was decreased significantly and Protocatechuric acid was produced in roots only.

1MeJA叶片处理能诱导叶片和根系中丙二烯氧化物环化酶基因、糖基转移酶（BX9）基因、苯丙氨酸转氨酶基因的表达，使叶片和根系中丁布含量升高，同时，6μL/L MeJA处理使第二叶中原儿茶酸含量显著降低，诱导根中产生原儿茶酸，使第二叶中香草酸含量和根中未知物质峰面积显著增大。

The results showed that (1) all the arteries tested had tachyphylaxis to peptidergic agonists;(2) the desensitization of the arteries tested to catecholamines was uneasy except BA;(3) the desensitizations to AⅡ, AVP and PE were homologous;(4) the endothelium-EDRF -cGMP pathway had no contribution to the tachyphylaxis of PA to AⅡ and AVP;(5) membrane receptor cycling (internaliation and re-insertion) contributed only in part to homologous desensitization;(6) there was no change in the function of voltage-dependent Ca〓 channel during desensitization to AⅡ and AVP;(7) some changes in G protein occurred during homologous desensitization;(8) the most surprising finding was that the caudal arterial smooth muscle of stroke-prone spontaneously hypertensive rat showed tachyphylaxis to α〓-adrenoceptor agonist PE, while the tachyphylaxis of pulmonary artery of SHR was not changed compared with that of Wistar rat.

脱敏是消除效应的一种有效方式。因此，研究不同血管对不同激动剂脱敏的差异及阐明脱敏的机制，有助于阐明血管活动个性化的机制。研究表明：血管对肽类激动剂的脱敏方式为快速脱敏，而对儿茶酚胺类激动剂不易脱敏；血管对肽类激动剂和儿茶酚胺类激动剂表现为同源脱敏；内皮-NO-cGMP通路不参与肺动脉对AⅡ和AVP的快速脱敏；用PAO抑制膜受体的内在化只能短暂抑制脱敏的发展，提示用膜受体数目的下调说不能完全解释同源脱敏；血管对AⅡ和AVP脱敏后VSMC细胞膜电压依赖性钙通道功能无改变；CA对AVP脱敏后GTPγS的量-效曲线下移，说明有G蛋白的变化，但这种变化并非G蛋白的亲和性改变；SHRsp之CA平滑肌对AⅡ和AVP的快速脱敏并未减弱，但对PE却表现为快速脱敏，这是我们首次发现的一个非常有趣的现象。

Results: Epinephrine significantly increased the lipid peroxidation of erythrocyte membrane up to 19%（P〈 0.05）, however, noradrenalin had little effect.

观察儿茶酚胺自氧化对红细胞的过氧化作用，并以乙肝病毒表面抗体为代表靶，观察儿茶酚胺自氧化对抗体活性的影响。

In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是，在否定句或疑问句里，这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷