儿茶

All dates were analyzed by the principal component analysis through using the SIMCA-P 10.0 software. Result: The PCA demonstrated that the metabolome between treated group and control group had difference in rat urine sample after of 22 days administrated, for treated group 169 kinds of biomarkers were found including oxalacetic acid, malic acid, 2-ketoglutaric acid, NE, arachidonic acid, 5-HIAA and other compounds, the result was consistent with pharmacological effects of R.coptidis , such as antiinflammatory, inhibiting biosynthesis of CA biosynthesis, anti-central nerve and energy metabolism inhibition.

结果：给药22 d，黄连组与对照组大鼠尿样代谢组有较大差异，发现了169个生物标记物，其中可能的化合物为草酰乙酸、苹果酸、2-酮戊二酸、去甲肾上腺素、花生四烯酸、5-羟吲哚乙酸等物质，这与黄连抗炎、阻止儿茶酚胺的生物合成、抑制中枢神经、降低能量代谢的药理作用相一致。

In the latter case the graft and host tissue mixed togethor. In the grafts there were yellow-green fluorescence-bearing catecholaminergic neurons and TH immunoreactive neurons appearing as fusiform or polyangular shape.

荧光显微镜下可见移植物内有发黄绿色荧光的儿茶酚胺能神经细胞，免疫细胞化学显示移植区内有TH阳性神经细胞，后者为梭形或多角形。

Objective To establish a HPLC method for the quantitative determination of tanshinol sodium and protocatechualdehyde in Danxiang Guanxin for injection.

目的建立用HPLC法测定注射用丹香冠心中丹参素钠和原儿茶醛含量的方法。

Results The content of Salvianolic acid B decreased with decocting time passing by,while the content of tanshinol and protocatechualdehyde increased.

结果随着煎煮时间的延长，丹参中的主要水溶性有效成分丹酚酸B的含量会而逐步降低；而同时，丹参素和原儿茶醛的含量则持续增加。

Object To establish a new method to determine protocatechualdehyde in Maodongqing Sustained-release Tablet.

目的 建立测定毛冬青缓释片中原儿茶醛含量的方法。

The in vitro release of the resultant products was studied by evaluating the marker of protocatechualdehyde at 312 nm using high efficiency liquid chromatography.

以原儿茶醛为检测标志物，高效液相色谱法测定312 nm处物质浓度，以了解体外释放情况。

The extracts of SM, danshensu and protocatechualdehyde, had ablood-lipid regulation by inhibiting cholesterol biosynthesis and increasing CYP7AmRNA expression when they were absorbed to blood.

丹参提取物及其有效成分丹参素和原儿茶醛可经胃肠道吸收入血而抑制内源性胆固醇的生物合成和增加肝细胞CYP7AmRNA表达发挥调脂作用。

Danshensu and protocatechualdehyde, the water soluble ingredients of SM, were absorbed to blood in rats by oral, and 75% ethanol and ammonia extracts of SM, sodium danshensu and protocatechualdehyde, obviously increased OD in the experiment of amphotercin B cell model and the expression of CYP7AmRNA in BRL cell line.

丹参水溶性成分丹参素和原儿茶醛口服后均能吸收入血，丹参75％乙醇提取物和丹参氨水提取物及其部分单体，在两性霉素B细胞模型实验中均能明显增加OD值，同时亦能明显增加肝细胞CYP7AmRNA表达。

In order to understand their mechanisms of blood-lipid regulation, We used the amphotercin B cell model and RT-PCR method to examine the effects of the serum-drugs of SM and FC extracts and their effective monomers, including danshensu, protocatechualdehyde, ursolic acid, quercetin and rutin, on cholesterol biosynthesis in CHO cells and the expressions of CYP7AmRNA and DGATmRNA in BRL cell line.

采用两性霉素B细胞模型和逆转录-聚合酶链反应方法，分别观察丹参和山楂各调脂有效部位以及部分单体(丹参素钠、原儿茶醛、熊果酸、槲皮素和芦丁)对内源性胆固醇合成、CYP7AmRNA和DGATmRNA表达的影响。

Results The linear ranges of tanshinol sodium and protocatechualdehyde were 42.52~382.68μg/mL and 8.14~ 73.30μg/mL, respectively; the correlation coefficients were 0.999 8 and 0.999 6, respectively; the average recoveries of spiked sample were 100.54%(RSD=0.797%) and 98.87%(RSD=1.282%), respectively.

结果丹参素钠在42.52~382.68μg/mL浓度范围内线性关系良好（r＝0.999 8），平均回收率为100.54%（RSD＝0.797%）；原儿茶醛在8.14~73.30μg/mL浓度范围内线性关系良好（r＝0.999 6）；平均回收率为98.87%（RSD＝1.282%）；结论此法简便，快速，准确。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。