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Parkinson's diseaseis basically a degeneration disorder of basal ganglia, and is characterized by tremor, akinesia, and rigidity, and sometimes may accompany with cognitive impairment similarity frontal lobe dysfunction.

中文摘要巴金森氏症是一种基底核的退化性疾病,临床症状除了震颤、运动不能及僵直外,常伴随类似额叶损伤的认知功能障碍,这些认知障碍一般以为是额叶-皮质下神经回路受损所导致。P300-事件性诱发电位,可以反应出人类的认知历程,常被用来检测大脑高级皮质功能的异常。

Stage 2: More relaxed state where larger muscle groups can be controlled and manipulated such as Arm Catalepsy.

第二级:更放松的状态,催眠师可以控制更大块的肌肉群,可暗示出像手臂僵直这样的现象。

Many studies have reported that Klebsiella pneumoniae is associated with ankylosing spondylitis but the mechanism of pathogenesis is remained unclear. The endoplasmic reticulum stress would be induced upon exposure of decapsulated KP in HLA-B27 expression B lymphoblast CA46 cells and non-HLA-B27 expression U937 monocytes. Our previous studies demonstrated that decapsulated KP could up-regulate BiP/Grp78 and calreticulin expressions in a dose- and time-dependent manner. We screen more than 60 kinds of traditional herbs and bioactivity agents and we found that berberine,taurine,extracts of Andrographis paniculata Nees.

许多研究指出克雷伯氏肺炎杆菌和僵直性脊椎炎有相当的关系,但是致病机制仍然不是很清楚,因此我们使用去荚膜克雷伯氏肺炎菌来诱发表现HLA-B27的CA46 B淋巴球母细胞、不含HLA-B27的U937单核球细胞可以产生内质网压力,我们先前的实验指出,随著剂量增加,去荚膜克雷伯菌能够过度调控内质网压力指标蛋白质BiP和Calreticulin表现增加。

1255Stephen's mother, emaciated, rises stark through the floor, in leper grey with a wreath of faded orangeblossoms and a torn bridal veil, her face worn and noseless, green with gravemould.

1255(斯蒂芬的母亲憔悴不堪,僵直地穿过地板出现了。她身穿癞病患者的灰衣服,手执枯谢的桔花环,披着扯破的婚纱。

Results: The important characters of early gastric carcinoma consisted of the nodular alteration of niche mouth and surface, mucosal irregular muster and manifestations of gastric wall such as roughness , stiffness, concavity, bilateralness, spiculate margin, destruction of mucosal micro folds and rough filling defects.

结果: 龛影口部和表面结节状改变,周围无一定规律的粘膜纠集,胃壁毛糙、僵直、凹陷、双边、边缘毛刺征,微皱襞的破坏和粗糙、充盈缺损是早期胃癌的重要特征。

Parkinson s disease is a degenerative disease of the basal ganglia causing tremor at rest, muscle rigidity and hypokinesia Gene therapy is most likely to cure PD completely, and the most promising one among all the treating ways But its effectiveness and safety have a strong relationship with the vectors chosed This article introduces some usually used virus vectors and their characteristics as well as the trend of virus vector in PD s gene therapy

帕金森病是一种神经节退行性疾病,主要以静止震颤,肌肉僵直和运动减少为临床症状。在其各种治疗方法中基因治疗最有望彻底治愈PD,最有发展前景。但其有效性与安全性与其所选用的载体有很大关系。本文介绍了基因治疗中常用的病毒载体以及它们的特性,并指出PD基因治疗中病毒载体的发展趋势。

She sat beside her sister, as unlike her in looks, with her dark hair and heavily lidded eyes, as she was in bearing and demeanor; where Narcissa sat rigid and impassive, Bellatrix leaned toward Voldemort, for mere words could not demonstrate her longing for closeness.

她坐在她妹妹旁边,十分不相像,她的深色头发和沉重的耷拉着的眼角,似乎在克制着承受着什么,纳西莎冷漠僵直地坐着,贝拉里丝则倾向伏地魔,似乎仅仅语言不能显示她对亲近的热切。

In experimental animals, exposure to a common herbicide, rotenone, induces features of Parkinsonism; mechanistically, rotenone-induced destruction of dopaminergic neurons has been attributed to its inhibition of the activity of neuronal mitochondrial complex Ⅰ.

例如,Greenamyre和他的同事在2000年报道了经大鼠颈静脉慢性灌流鱼藤酮复制了帕金森病的主要特征,包括选择性黑质纹状体多巴胺系统变性,Lewy小体样细胞浆包涵体形成和一些行为变化,例如运动减少和僵直等。从发病机制上考虑,鱼藤酮诱导的多巴胺神经通路损伤被认为是由鱼藤酮抑制线粒体复合体Ⅰ活性引起的。

For an instant, I felt a thrill ofgenuine fear, raising the hair on my arms. The look only lasted a second,but it chilled me more than the freezing wind. He turned back to the

可爱德华·卡伦的背都僵直了,接着他慢慢地扭过头来瞪了我一眼--他的脸漂亮得不可思议--锐利的目光里充满了仇恨。

For supracondylar fracture of humerus with obvious displacement,it is easy to make reduction,but the fixation and the maintenance of reduction is not easy; manual reduction with plaster or splint immobilization,though as the first-chosen method,has such shortcomings as infirm or loosening fixation of plaster or splint which may cause injury to blood vessels or nerves; open reduction may lead to further trauma to soft tissues and tissue adhesion,and to joint stiffness; the closed reduction with cross Kirschners wires under C-arm X-ray can avoid the above mentioned shortcomings and it is easy in operation.

移位明显的肱骨髁上骨折,复位容易,但固定及维持复位困难,手法复位石膏或夹板外固定虽是首选治疗方法,但石膏或夹板固定不牢固,易出现松动甚至可造成血管及神经损伤,而切开复位更易进一步造成软组织创伤,组织粘连,最终导致关节僵直功能障碍。本组C臂下闭合复位交叉克氏针治疗移位明显的肱骨髁上骨折避免了上述缺点,而且方法简单。肱骨髁上骨折;经皮克氏针固定;儿童;闭合复位

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。