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These women, ages 61, 72 and 74 years, receiving long-term pergolide therapy for Parkinson's disease or restless legs syndrome, had valvular abnormalities strikingly similar to those induced by fenfluramine, ergot derivatives, or carcinoid. All three had severe, unexplained tricuspid regurgitation; two had predominantly right-sided congestive heart failure; and two had moderate aortic and mitral valve regurgitation. Histology revealed surface fibroproliferative lesions with preserved underlying valve architecture. Carcinoid was excluded, and none of the patients had taken anorectic drugs or ergots other than pergolide.

这3位妇女年龄分别为61、72及74岁,都长期服用pergolide来治疗帕金森氏症或睡眠脚动症,而且也都有不明原因的严重三尖瓣闭锁不全,就像因fenfluramine、麦角衍生物,或类癌肿瘤所引起的瓣膜异常情形一样;其中2位主要有右心衰竭,2位有中度的主动脉及二尖瓣的闭锁不全,组织学检查显现表面有纤维增生性的损伤,但瓣膜的结构仍然还在;类癌是被排除在外的,而且这3位妇女除了pergolide之外,都不曾服用过厌食剂或麦角类药物。

The team, who presented their results at a joint meeting of the American Association for Cancer Research and the International Association for the Study of Lung Cancer in Coronado, California, this week, are now investigating whether their putative cancer stem cells are more resistant than run-of-the-mill cancer cells to chemotherapy or radiation, as research on other putative stem cells has suggested.

本周,在加利福尼亚州科罗纳多举行的美国癌症研究学会和国际肺癌研究学会联合会议上,该小组公布了他们的研究结果。他们现在正在研究假定的肿瘤干细胞是否像其他假定干细胞上的研究显示的一样,比普通癌细胞更耐化疗及放疗。

"Because some of these cancers…are hard to screen with current imaging techniques, further development of fecal DNA as a pan-detection assay for gastrointestinal tract cancers represents an intriguing and exciting new frontier," the editorialist writes.

这位评论者写道:"目前的成像技术很难检测这些肿瘤,将粪便DNA检测作为广泛的胃肠道检测方法的想法为我们打开一个有趣而令人激动的新领域。"

"Tamoxifen is a good drug, but it looks like aromatase inhibitors may be somewhat better," says James Ingle, MD, a professor of oncology at Mayo Clinic, who is presenting the results on behalf of the Aromatase Inhibitors Overview Group.

"他莫昔芬是一个很好的药物,但它看起来像芳香酶抑制剂可能会好一些,"詹姆斯说,英格尔,医学博士,教授,肿瘤在梅奥诊所,是谁提出的结果代表的芳香化酶抑制剂总览集团。

The reconstruction with mip show that the percent of excellent was 67.2% and the worse was 32.8%.the accuracy of diagnosis respectively was 86.7%,50.0%,80.0%,77.8% and 50.0%.conclusion according to ureteral tract brightness,high image quality and high success rate with correctly reconstruction can delineate ureter cubicity,which is helpful in diagnosing and instructing clinical treatment.

mip显示:图像评级为优良39例(67.2%),评级为差19例(32.8%)。疾病判断的准确度为:结石86.7%、肿瘤50.0%、囊肿80.0%、先天性狭窄77.8%、炎症50.0%。结论根据输尿管显像程度,选择合适的重建方法完整显示输尿管与疾病的解剖关系,有助于疾病的诊断和指导临床治疗。 x线计算机;输尿管造影;诊断;重建

The clinical therapeutic strategies were changed in 22 cases due to the results of PET/CT,and the influence rate of PET/ CT was 28.6 %(22/77).Conclusion PET/CT can detect the primary lesions, recurrence and metastasis of gastrointestinal tumor with high sensitivity and accuracy. 18F-FDG PET/CT imaging has increased accuracy of the diagnosis, staging, restaging for gastrointestinal tumor.

PET/CT能准确、灵敏地检测胃肠道肿瘤原发病灶、转移以及复发病灶,对临床治疗决策有重要影响。18F-FDG PET/CT显像对胃肠道恶性肿瘤的分期、术后再分期诊断有较高的临床价值。

Our research included four parts: design and synthesis of amine oximes and other compounds as ligands, label them with 〓Tc〓, assessment of their biological activities in vitro and in vivo, and preparation of 〓 kit for clinic use.

研究工作主要包括合成作为配体的〓及其类似物,制备其〓Tc〓标记物,进行乏氧细胞实验和荷瘤动物实验,考察它们在肿瘤细胞中的吸收与体系乏氧的关系,以及在不同荷瘤动物模型中的放射性分布和显像情况。

The relationship between parasagittal meningiomas and draining veins of brain surface can be identified by MR brain surface anatomy scanning, which can evaluate the draining veins correctly and direct to protect the key draining vein, especially the draining vein in functional area of brain surface. It plays important role in the protection of neurological function and the recovery of the postoperation.

磁共振脑表面成像技术能在术前明确矢状窦旁脑膜瘤与脑表面回流静脉之间关系,可在术前对患者肿瘤表面脑回流静脉做出正确的评估,对脑表面重要回流静脉的保护提供了准确的影像学依据,对患者神经功能的保护及术后恢复起到重要作用。

Methods: 22 cases of parasagittal meningiomas, which diagnosed by CT and MRI preoperation, confirmed by pathology postoperation in hospital from 2006.9 to 2008.1 of Second Affiliated Hospital of Zhejiang University, were evaluated the ambient draining vein of the tumor by MR brain surface anatomy scanning.

分析本院经头颅 CT 及 MRI 诊断为矢状窦旁脑膜瘤,利用显微手术技术切除并经病理证实的的22例患者;术前均运用磁共振脑表面成像技术评估与肿瘤关系密切的脑表面回流静脉情况。

PURPOSE: To retrospectively assess accuracy of magnetic resonance imaging after radiation therapy with concomitant chemotherapy for downsizing of the primary lesion to ypT0-2 tumor confined to rectal wall in locally advanced rectal cancer, with histopathologic findings as reference standard, and to evaluate additional value of volumetric analysis.

目的:对局部进展期直肠癌进行化疗同时辅以放疗,使其原始病灶至缩小至局限于直肠壁的ypT0 – 2肿瘤,以组织病理学结果作为参考标准回顾性评价其磁共振成像的精确性,同时评估体积分析的额外价值。

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They weren't aggressive, but I yelled and threw a rock in their direction to get them off the trail and away from me, just in case.

他们没有侵略性,但我大喊,并在他们的方向扔石头让他们过的线索,远离我,以防万一。

In slot 2 in your bag put wrapping paper, quantity does not matter in this case.

在你的书包里槽2把包装纸、数量无关紧要。

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密封,遮光,置阴凉干燥处。