催化的

Abrin is one of the potent toxins isolated from the beans of plant abrus precatorius.the toxic protein consists of two disulfide-bonded subunits,the a and b chains.the b chain is a galactose-specific lectin that facilitates the binding of abrin to the cell membrane that precedes endocytosis.after entering the cells,the a chain catalytically inactivates 60s ribosomal subunits by removing adenine position 4324 of 28s r–rna,and thereby inhibits protein biosynthesis.

相思子毒素是从豆科植物(abrus precatorius l。)种子中分离的一种细胞毒性蛋白。它由a，b两条链组成，由一个二硫键相联，b链具有半乳糖凝集活性，可与细胞膜上受体结合，帮助a链进入细胞内，a链进入细胞催化失活60s核糖体亚基，从而使细胞蛋白合成被抑制。

Want smooth accelerant only so not by purify, its catalysis is permanent.

所以只要光触媒不被去除，其催化作用就是永久的。

To obtain new functional aromatic polymer material, the reaction of acenaphthene with nitrobenzene under high active catalyst of AlCl3 was investigated at room temperature and ambient atmosphere.

为制备更多新型功能高分子中间体，研究了高活性lewis酸AlCl3催化作用下，苊与硝基苯在温和条件常温常压下的反应。

To obtain new functional aromatic polymer intermediates, the coupling reaction of acenaphthene catalyzed by inorganic salts, such as AlCl3, FeCl3, ZnCl2 and ionic liquid(Cl/FeCl3) was investigated at room temperature and ambient atmosphere.

为合成新型功能高分子中间体，分别研究了在AlCl3， FeCl3， ZnCl2等无机盐和Cl/FeCl3离子液体催化作用下，苊在温和条件常温常压下的偶联反应。

The ozonation of acetaldehyde was the first order reaction of ozone.

乙醛催化臭氧氧化反应是臭氧浓度的一级反应。

The results show that a little amount of heteropolymolybdovanadophosphate can remarkably speed the degradation, the best conditions of the oxidative degradation of chitosan with hydrogen peroxide catalized by heteropolymolybdovanadophosphate in homogeneous condition are as follows: the ratio of catalyst and chitosan is 1 to 10, concentration of hydrogen peroxide is 0.15%, the temperature is 80℃, reaction time is 2h. 0.2g chitosan was degraded under the best condition and the molecular weight by viscometry was degraded from 1460000 to 7812. then water-soluble chitosan was obtained by this method; The heterogeneous method is a high efficient way, the best condition of this method are as follows: the ratio of catalyst and chitosan is 2 to 100, the volume of 30% hydrogen peroxide is about 3mL, the temperature is 90℃, reaction time is 5min～30min.

研究结果表明，适量磷钼钒的存在可显著加速壳聚糖的降解，磷钼钒催化过氧化氢均相氧化降解壳聚糖的适宜反应条件是：催化剂与壳聚糖的质量比为1∶10、过氧化氢百分浓度为0.15％、反应温度为80℃、反应时间为2h，在此条件下对0.2g溶解在100 mL 0.5％稀醋酸中的壳聚糖进行降解，可使壳聚糖的粘均分子量由原来的146万下降到七千多(7812)，成为水溶性低分子量壳聚糖，从而达到应用的要求；在异相条件下以磷钼钒为催化剂催化过氧化氢氧化降解壳聚糖是一种高效快速的方法，此法降解壳聚糖的最佳反应条件是：催化剂与壳聚糖的质量比为2∶100；30％过氧化氢的用量为3mL左右；反应温度为90℃、反应时间为5min～30min。

The dissertation mainly consists of two parts:1. The Reaction Chemistry of Alkynes under Palladium Catalysis Part 1 studies the reaction α,β-unsaturated carbonyl compounds with alkenylpalladium intermediate generated by nucleopalladation, and discovered 1 the Pd-catalyzed tandem addition reaction of halides, alkynes and α,β-unsaturated carbonyls,2 the four-component tandem addition reaction of halides, alkynes and α,β-unsaturated carbonyls, 3 the tandem intramolecular oxypalladation-conjugate additionreaction of alkynoic acids with α,β-enals. These new reactions provide notonly efficient highly stereoselective methods for the synthesis of γ,δ-unsaturated,polyunsaturated carbonyl compounds and γ-lactonic aldehydes, but also thebasic transformations for a number of C-C bond formation reactions which can be usedto design synthesis of many acyclic, cyclic or polycyclic compounds.

本论文的主要工作分为两个部分：一、钯催化下炔烃的反应化学在本小组前人工作的基础上，我们详细研究了炔烃亲核钯化产生的烯基钯中间体与α，β-不饱和羰基化合物的反应，发现两价钯催化下卤离子-炔烃-α，β-不饱和醛酮的串联加成反应、卤离子-炔烃-α，β-不饱和醛酮的西组分串联加成及炔酸分子内氧钯化-串联Michael型加成反应；由此发展了γ，δ-不饱和醛酮、多不饱和羰基化合物和带有醛酮基侧链的γ-丁内酯衍生物的高立体选择性合成方法，这一过量卤离子存在下的烯基钯对α，β-不饱和羰基化合物共轭加成反应的发现，为大量碳-碳键形成反应的实现提供了基础，使我们能够从这一基本反应出发，设计和开发多种分子内、分子间的碳碳成键反应，以好的立体、区域选择性组建开链、环状及多环类型的化合物。

Glioma is still one of refractory disease in the neurosurgical field; the development of new primary and adjuvant treatment is vital. Recently, the gene therapy of glioma is developed rapidly and there are many methods about the gene therapy that include: suicide gene therapy, immunologic gene therapy, drug resistangce gene therapy, angiostatin gene therapy and so on. The sucide gene therapy is the most potential approach of antitumer, these nonmammalian genes encode enzyme that convert nontoxic prodrugs into highly toxic metablites. Cells transfected with suicide genes are targeted for specific negative selection, witch can be induced by administrtion of the corresponding produg. Among the enzyme/produg combinations, two of the best characterized system are herpes simplex virus thymidine kinase /ganciclovir and Escherichia coli cytosine deaminase /5-flourocytosine (5-FC). The formor can convert the antiviral nucleoside analogs acyclovir , ganciclovir to their nucleoside monophosphate derivatives, the monophosphate forms are subsequently phosphorylated by endogenus cellular kinases to triphosphates, these molecules are potent inhibitors of DNA synthesis.

近年来脑胶质瘤的基因治疗发展迅速，应运而生的方法有自杀基因、免疫基因、多药耐药基因以及抗血管生成基因等，其中自杀基因被认为是最有前景的基因治疗方法，它又称病毒介导的酶／药物前体疗法，是利用转基因技术将哺乳动物细胞中所不含有的自杀基因转入到哺乳动物肿瘤细胞中，该基因表达的产物可将无毒的药物前体转化为毒性药物，从而选择性杀伤该肿瘤细胞，常用的自杀基因有单纯疱疹病毒-胸苷激酶基因和大肠杆菌胞嘧啶脱氨酶基因，前者催化无毒性抗病毒核苷类似物如丙氧鸟苷、无环鸟苷等成为单磷酸核苷衍生物，然后在内源性细胞激酶作用下转化为具有明显毒性的三磷酸核苷，作为DNA合成链的终止剂和DNA合成酶的抑制剂，干扰细胞DNA的合成；后者编码的胞嘧啶脱氨酶可催化5-氟胞嘧啶（5-FC）脱氨成为5-氟尿嘧啶（5-FU），然后代谢为有毒性的5-氟尿嘧啶-5′三磷酸（5-FUTP）和5-氟-2′脱氧尿嘧啶-5′磷酸（5-FdUTP），5-FUTP通过与UTP竞争性结合而抑制mRNA和tRNA的合成，5-FdUTP则作用于胸苷合成酶，导致TMP衰竭而阻止DNA的合成，最终诱导肿瘤细胞凋亡。

By means of the plating technology and the system designed and made ourselves, we call them as the direct-heat evaporating roll-pulled with vacuum piston and the helix evaporating of straight heat-wire with the negative thermal specific resistance , the align polishing ring films and the separating ones of pure gold have been plated directly at the inner wall of the capillary of Sealed-off CO〓 laser.

简便有效地使器件的输出功率、光束品质、稳定性和使用寿命都得以提高的作用效果；分析了放电驱动催化机理及催化效果与器件参数、工作状态及其中的等离子体过程的对应关系，建立了数学模型，编程数值计算了放电管内正柱区中等离子体参数分布及其与器件工作外参数的关系；利用我们设计开发的直热式真空活塞卷拖和负阻直热丝螺旋蒸镀工艺及制作的系统，在封离型CO〓激光器毛细管玻璃内壁上直接镀制出了单质金的镜面环膜和离散膜，经理论分析和实验检验，指出美国专利4756000号的环金方案将导致器件工作特性的改变和恶化，降低效率；肯定了正柱区边界部分场对建立良好的激光振荡的作用意义，明确提出了①作为高品质器件设计基础的弥散膜催化剂；②高斯管型弦驻波振动定型磨制、检测的新概念及相应的制备加工工艺；实际制出了管子，测定了其基本的工作特性和初期过程。

The result show that the N elements curbed the transition from anatase phase to rutile phase , Doped-N was in the structure of the TiO2 as the form of Ti-O-N and formed a new bond energy level;N-doped changed the paramagnetic of the characteristics. The paramagnetic resonance spectrum of TiO2 showed anisotropic and showed hyperfine splitting, The Lande factor of Ti3 + combined with the N is 1.956. UV-Vis absorption spectra showed that the photocatalytic ability of photocatalyst TiO2-xNx to expand to the visible region, the sample (3.84wt %) has the highest photo catalytic activity, the adsorption edge extend to 520nm and degradation is 55.54% under the visible light for 1.5h.

研究结果显示，N元素抑制了锐钛矿相向金红石相的转变，阻止了晶粒的长大，掺杂的N元素以O-Ti-N的形式存在于光催化剂结构中，形成了新的能级结构；N掺杂改变了催化剂的顺磁特征，使TiO2的顺磁共振谱线呈现各向异性，发生了超精细分裂，其中g2=1.956，是与N结合的Ti3+的朗德因子；紫外可见光吸收谱表明，催化剂TiO2-xNx的光响应能力拓展到可见光区，光吸收带发生红移；光催化测试结果显示，掺杂量为3.84的TiO2-xNx在可见光区的响应能力最高，吸收波长延伸至520nm，其光催化活性最大，1.5h降解率达到55.54%。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。